brequinar has been researched along with Head and Neck Neoplasms in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peters, GJ | 1 |
| Armand, JP; Barbu, M; Carde, P; Chabot, GG; de Forni, M; Domenge, C; Fontana, X; Gouyette, A; Recondo, G | 1 |
| Adams, D; Carlson, R; Cripps, C; Dallaire, B; Doroshow, J; Grillo-Lopez, A; Gyves, J; Robert, F; Urba, S; Velez-Garcia, E | 1 |
| Braakhuis, BJ; Peters, GJ; Snow, GB; van Dongen, GA; van Walsum, M | 1 |
2 trial(s) available for brequinar and Head and Neck Neoplasms
| Article | Year |
|---|---|
Phase I and pharmacokinetic study of brequinar (DUP 785; NSC 368390) in cancer patients.
Topics: Adult; Aged; Antineoplastic Agents; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Genital Neoplasms, Female; Half-Life; Head and Neck Neoplasms; Humans; Infusions, Intravenous; Male; Middle Aged; Thrombocytopenia | 1993 |
Multicenter phase II trial of brequinar sodium in patients with advanced squamous-cell carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Agents; Biphenyl Compounds; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged | 1992 |
2 other study(ies) available for brequinar and Head and Neck Neoplasms
| Article | Year |
|---|---|
Antipyrimidine effects of five different pyrimidine de novo synthesis inhibitors in three head and neck cancer cell lines.
Topics: Amides; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Biphenyl Compounds; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carcinoma, Squamous Cell; Cell Line, Tumor; Dihydroorotate Dehydrogenase; Head and Neck Neoplasms; Humans; Isoxazoles; Naphthoquinones; Orotate Phosphoribosyltransferase; Oxidoreductases Acting on CH-CH Group Donors; Phosphonoacetic Acid; Purine Nucleotides; Pyrazoles; Pyrimidine Nucleotides; Ribonucleosides; Ribose | 2018 |
Antitumor activity of brequinar sodium (Dup-785) against human head and neck squamous cell carcinoma xenografts.
Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Carcinoma, Squamous Cell; Dihydroorotate Dehydrogenase; Drug Evaluation, Preclinical; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Transplantation, Heterologous | 1990 |