brartemicin has been researched along with Colonic-Neoplasms* in 1 studies
1 other study(ies) available for brartemicin and Colonic-Neoplasms
Article | Year |
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Brartemicin, an inhibitor of tumor cell invasion from the actinomycete Nonomuraea sp.
Brartemicin (1), a new trehalose-derived metabolite, was isolated from the culture broth of the actinomycete of the genus Nonomuraea. Its structure and absolute configuration were determined by spectroscopic analyses. The new compound inhibited the invasion of murine colon carcinoma 26-L5 cells with an IC(50) value of 0.39 microM in a concentration-dependent manner without showing cytotoxic effects. Topics: Actinobacteria; Animals; Antineoplastic Agents; Artemisia; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Inhibitory Concentration 50; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Trehalose | 2009 |