bosentan anhydrous has been researched along with Skin Ulcer in 59 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 18 (30.51) | 29.6817 |
| 2010's | 36 (61.02) | 24.3611 |
| 2020's | 5 (8.47) | 2.80 |
| Authors | Studies |
|---|---|
| Endo, Y; Ishikawa, M; Motegi, SI; Sekiguchi, A; Uchiyama, A; Yamazaki, S | 1 |
| Allanore, Y; Alunno, A; Baron, M; Campochiaro, C; Chung, L; Denton, CP; Distler, O; Frech, T; Furst, DE; Giuggioli, D; Hughes, M; Khanna, D; Krieg, T; Kuwana, M; Maltez, N; Matucci-Cerinic, M; Moinzadeh, P; Pope, J; Ross, L; Schoones, JW; Suliman, YA | 1 |
| Berry-Cabán, CS; Black, L; De Blasio, DC; Huh, J; Tracy, CL | 1 |
| Ju, JH; Kim, BY; Kim, HS; Kim, SH; Kim, YS; Lee, KA; Park, S; Son, CN | 1 |
| Abuowda, Y; Almeida, RS; Matos-Costa, J; Oliveira, AA; Pego, P; Santos, C | 1 |
| Cutolo, M; Paolino, S; Pizzorni, C; Ruaro, B; Sulli, A | 1 |
| Combalia, A; Giavedoni, P; Grau-Junyent, JM; Mascaró, JM; Tamez, L | 1 |
| Abignano, G; Allanore, Y; Avouac, J; Bellando-Randone, S; Blagojevic, J; Cometi, L; Czirják, L; Del Galdo, F; Denton, CP; Distler, O; Frerix, M; Guiducci, S; Huscher, D; Jaeger, VK; Lóránd, V; Matucci-Cerinic, M; Maurer, B; Müller-Ladner, U; Nihtyanova, S; Riemekasten, G; Siegert, E; Tarner, IH; Vettori, S; Walker, UA | 1 |
| Abignano, G; Allanore, Y; Avouac, J; Bellando-Randone, S; Blagojevic, J; Bruni, C; Cometi, L; Czirják, L; Del Galdo, F; Denton, CP; Distler, O; Frerix, M; Guiducci, S; Huscher, D; Jaeger, VK; Lóránd, V; Matucci-Cerinic, M; Maurer, B; Moggi-Pignone, A; Müller-Ladner, U; Nihtyanova, S; Riemekasten, G; Siegert, E; Tarner, IH; Vettori, S; Walker, UA | 1 |
| Catarsi, E; Doveri, M; Tavoni, A | 1 |
| Romaniello, A; Rosato, E; Salsano, F; Viola, G | 1 |
| Denton, CP; Ngcozana, T; Ong, V | 1 |
| Bloemsaat-Minekus, JP; Meijs, J; Vonk, MC; Voskuyl, AE | 1 |
| Acin, F; Bleda, S; De Haro, J | 1 |
| Belz, D; Hunzelmann, N; Moinzadeh, P | 1 |
| Olivé, A; Prior, Á; Rodriguez-Muguruza, S; Sanint, J | 1 |
| Sharabi, I; Tanay, A; Zandman-Goddard, G | 1 |
| Bernal, M; De Cata, A; De Cosmo, S; Inglese, M; Mazzoccoli, G; Molinaro, F; Rubino, R | 1 |
| Asano, Y; Endo, H; Hamaguchi, Y; Ihn, H; Kawaguchi, Y; Kuwana, M; Motegi, SI; Sumida, T; Takehara, K; Tanaka, S | 1 |
| Beissert, S; Distler, JH; Kreuter, A; Müller-Ladner, U; Riemekasten, G | 1 |
| Amoroso, D; Barbano, B; Di Paolo, M; Gigante, A; Palange, P; Romaniello, A; Rosato, E; Tallerini, G | 1 |
| Agard, C; Bérezné, A; Carpentier, PH; Clerson, P; Diot, E; Duval-Modeste, AB; Gressin, V; Hachulla, E; Jego, P; Lok, C; Mouthon, L; Puzenat, E; Richard, MA; Sparsa, A; Van Kien, AK | 1 |
| Blaise, S; Cracowski, JL; Forli, A; Imbert, B; Roustit, M | 1 |
| Heresi, GA; Minai, OA | 1 |
| Ishikawa, O; Nagai, Y; Shimizu, A | 1 |
| Matucci-Cerinic, M; Seibold, JR | 1 |
| Denton, CP; Matucci-Cerinic, M; Pope, JE; Steen, V | 1 |
| Kanno, T; Kyozuka, H; Nishida, T; Ohira, H; Suzuki, E | 1 |
| Alamanos, Y; Argyriou, E; Botzoris, V; Drosos, AA; Tsifetaki, N; Zioga, A | 1 |
| Dhillon, S | 1 |
| Bambara, LM; Biasi, D; Caramaschi, P; Mahamid, H | 1 |
| Felder, G; Gensch, K; Haust, M; Kuhn, A; Ohmann, C; Ruland, V; Ruzicka, T; Verde, P; Weber, R | 1 |
| Arrébola López, MA; Hernández, MM; Todoli Parra, JA | 1 |
| Bredemeier, M | 1 |
| Black, CM; Carpentier, P; Denton, CP; Doyle, MK; Fessler, BJ; Furst, DE; Hellmich, B; Hsu, VM; Korn, JH; Kramer, F; Matucci-Cerinic, M; Mayes, MD; Medsger, TA; Merkel, PA; Morganti, A; Pope, JE; Seibold, JR; Sweiss, NJ; Wigley, FM | 1 |
| Weinerth, J; Wiesent, F | 1 |
| Pope, J; Zelenietz, C | 1 |
| Lambova, S; Müller-Ladner, U | 1 |
| Botzoris, V; Drosos, AA | 1 |
| Asano, Y; Hatano, M; Ichimura, Y; Kawashima, T; Kinugawa, K; Kogure, A; Mitsui, H; Miyazaki, M; Sato, S; Sugaya, M; Takahashi, T; Takekoshi, T; Tamaki, Z; Taniguchi, T; Tomita, M; Yao, A | 1 |
| Alegre Sancho, JJ; Castillo, MJ; Egurbide, MV; Fonollosa, V; Lloria, X; Roman Ivorra, JA; Simeon, CP | 1 |
| Brodmann, M; Froehlich, H; Hafner, F; Steidl, K; Thomas, G | 1 |
| Cervigón-González, I; Palomo-Arellano, A; Torres-Iglesias, LM | 1 |
| Hunzelmann, N; Krieg, T; Moinzadeh, P | 1 |
| Kurgyis, Z; Lang, MU; Ruzicka, T; Sárdy, M; Sick, I; Varga, R | 1 |
| Hasegawa, M; Hattori, T; Ishikawa, O; Nagai, Y; Okada, E; Tago, O | 1 |
| Hoffmann, U; Kuhn, A; Riemekasten, G; Sunderkötter, C; Weiss, N | 1 |
| Cardarelli, S; Cozzi, F; Favaro, M; Pigatto, E; Punzi, L; Riato, L; Rizzo, M; Zanatta, E | 1 |
| Cabane, J; Humbert, M | 1 |
| Black, C; Carpentier, P; Chatterjee, S; Coppock, J; Denton, CP; Furst, D; Gaitonde, M; Guillevin, L; Hachulla, E; Herrick, A; Hsu, V; Korn, JH; Matucci Cerinic, M; Mayes, M; Merkel, PA; Molitor, J; Nguyen, N; Peter, HH; Pope, J; Rainisio, M; Rich, E; Seibold, JR; Simms, R | 1 |
| Varga, J | 1 |
| Grau, RG; Jacobs, MR; Knox, KS; Snyder, MJ; Wilkes, DS | 1 |
| Boullanger, N; Carpentier, P; Diot, E; Fain, O; Hachulla, E; Hatron, PY; Jego, P; Launay, D; Mouthon, L; Pasquier, E | 1 |
| Chevallier, D; Hervé, F; Levesque, H; Marie, I; Muir, JF; Tillon, J | 1 |
| Jain, M; Varga, J | 1 |
| Castro, Mdel C; Collantes, E; Miranda, MD; Moreno, JC; Morote, G; Roldan, R | 1 |
| Chamaillard, M; Constans, J; Heliot-Hosten, I; Taïeb, A | 1 |
| Guillevin, L | 1 |
| Beltrán Gutiérrez, J; Carmona, L; Díaz-Miguel, C; Gámir Gámir, ML; García de la Peña-Lefebvre, P; Orte Martínez, J; Rodríguez Rubio, S; Valero Expósito, M; Zea Mendoza, AC | 1 |
9 review(s) available for bosentan anhydrous and Skin Ulcer
| Article | Year |
|---|---|
Systemic pharmacological treatment of digital ulcers in systemic sclerosis: a systematic literature review.
Topics: Adult; Bosentan; Fingers; Humans; Scleroderma, Systemic; Skin Ulcer | 2023 |
Bosentan in systemic sclerosis.
Topics: Animals; Antihypertensive Agents; Bosentan; Endothelin Receptor Antagonists; Humans; Hypertension, Pulmonary; Lung Diseases, Interstitial; Scleroderma, Systemic; Skin Ulcer; Sulfonamides | 2008 |
Digital ulcers and outcomes assessment in scleroderma.
Topics: Bosentan; Fingers; Hand Dermatoses; Humans; Iloprost; Ischemia; Scleroderma, Systemic; Severity of Illness Index; Skin Ulcer; Sulfonamides; Treatment Outcome; Vasodilator Agents | 2008 |
Digital ulcers: overt vascular disease in systemic sclerosis.
Topics: Antihypertensive Agents; Bosentan; Databases, Factual; Endothelium, Vascular; Fingers; Hand Dermatoses; Humans; Raynaud Disease; Scleroderma, Systemic; Skin Ulcer; Sulfonamides | 2009 |
Bosentan: a review of its use in the management of digital ulcers associated with systemic sclerosis.
Topics: Bosentan; Drug Interactions; Endothelin A Receptor Antagonists; Endothelium, Vascular; Fingers; Humans; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Treatment Outcome | 2009 |
Differences in disability as measured by the Health Assessment Questionnaire between patients with and without digital ulcers in systemic sclerosis: a post hoc analysis of pooled data from two randomised controlled trials in digital ulcers using bosentan.
Topics: Antihypertensive Agents; Bosentan; Disability Evaluation; Fingers; Hand Dermatoses; Humans; Randomized Controlled Trials as Topic; Scleroderma, Systemic; Skin Ulcer; Sulfonamides | 2010 |
Management of Raynaud's phenomenon and digital ulcers in systemic sclerosis.
Topics: Bosentan; Calcium Channel Blockers; Cardiovascular Agents; Endothelin Receptor Antagonists; Enzyme Inhibitors; Fingers; Humans; Phosphodiesterase 5 Inhibitors; Prostaglandins I; Raynaud Disease; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Vasodilator Agents | 2011 |
[Management of digital ulcers in patients with systemic sclerosis].
Topics: Antihypertensive Agents; Bosentan; Endothelin Receptor Antagonists; Female; Fingers; Humans; Iloprost; Ischemia; Male; Raynaud Disease; Risk Factors; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Vasodilator Agents | 2012 |
Bosentan for the treatment of systemic sclerosis-associated pulmonary arterial hypertension, pulmonary fibrosis and digital ulcers.
Topics: Animals; Bosentan; Drug Tolerance; Humans; Hypertension; Pulmonary Fibrosis; Scleroderma, Systemic; Skin Ulcer; Sulfonamides | 2006 |
10 trial(s) available for bosentan anhydrous and Skin Ulcer
| Article | Year |
|---|---|
Classification, categorization and essential items for digital ulcer evaluation in systemic sclerosis: a DeSScipher/European Scleroderma Trials and Research group (EUSTAR) survey.
Topics: Adult; Bosentan; Calcium Channel Blockers; Drug Therapy, Combination; European Union; Female; Fingers; Humans; Iloprost; Male; Middle Aged; Prospective Studies; Scleroderma, Systemic; Sildenafil Citrate; Skin Ulcer; Surveys and Questionnaires | 2019 |
Use of vasoactive/vasodilating drugs for systemic sclerosis (SSc)-related digital ulcers (DUs) in expert tertiary centres: results from the analysis of the observational real-life DeSScipher study.
Topics: Adult; Aged; Bosentan; Drug Therapy, Combination; Europe; Female; Fingers; Humans; Iloprost; Male; Middle Aged; Prospective Studies; Scleroderma, Systemic; Sildenafil Citrate; Skin Ulcer; Treatment Outcome; Vasodilator Agents; Wound Healing | 2020 |
Blood flow in the hands of a predefined homogeneous systemic sclerosis population: the presence of digital ulcers and the improvement with bosentan.
Topics: Adult; Aged; Analysis of Variance; Bosentan; Case-Control Studies; Drug Administration Schedule; Female; Hand; Humans; Male; Middle Aged; Prospective Studies; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Treatment Outcome; Vasodilator Agents | 2015 |
An open-label study on long-term outcomes of bosentan for treating ulcers in thromboangiitis obliterans (Buerger's disease).
Topics: Adult; Bosentan; Endothelin Receptor Antagonists; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Skin Ulcer; Sulfonamides; Thromboangiitis Obliterans; Time Factors; Treatment Outcome; Young Adult | 2014 |
Safety and tolerability of bosentan for digital ulcers in Japanese patients with systemic sclerosis: Prospective, multicenter, open-label study.
Topics: Administration, Oral; Adult; Aged; Anemia; Arthralgia; Bosentan; Constipation; Diarrhea; Endothelin Receptor Antagonists; Female; Fingers; Herpes Zoster; Humans; Japan; Liver; Liver Function Tests; Male; Middle Aged; Prospective Studies; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Treatment Outcome; Wound Healing | 2017 |
Effect of bosentan on skin fibrosis in patients with systemic sclerosis: a prospective, open-label, non-comparative trial.
Topics: Aged; Bosentan; Endothelin Receptor Antagonists; Female; Fibrosis; Humans; Male; Middle Aged; Receptors, Endothelin; Scleroderma, Systemic; Skin Ulcer; Statistics as Topic; Sulfonamides; Treatment Outcome | 2010 |
Bosentan treatment of digital ulcers related to systemic sclerosis: results from the RAPIDS-2 randomised, double-blind, placebo-controlled trial.
Topics: Adult; Bosentan; Double-Blind Method; Drug Administration Schedule; Endothelin Receptor Antagonists; Female; Fingers; Hand Dermatoses; Humans; Male; Middle Aged; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Treatment Outcome; Wound Healing | 2011 |
Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist.
Topics: Activities of Daily Living; Administration, Oral; Antihypertensive Agents; Bosentan; Disability Evaluation; Double-Blind Method; Endothelin Receptor Antagonists; Female; Fingers; Health Status; Humans; Ischemia; Male; Middle Aged; Scleroderma, Systemic; Severity of Illness Index; Skin Ulcer; Sulfonamides; Surveys and Questionnaires; Treatment Outcome | 2004 |
New hope for systemic sclerosis patients with digital ulcers.
Topics: Administration, Oral; Bosentan; Chemical and Drug Induced Liver Injury; Double-Blind Method; Endothelin Receptor Antagonists; Fingers; Foot Dermatoses; Hand Dermatoses; Humans; Scleroderma, Localized; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Toes; Treatment Outcome | 2005 |
Long-term experience of bosentan for treating ulcers and healed ulcers in systemic sclerosis patients.
Topics: Adolescent; Adult; Aged; Bosentan; Child; Endothelin Receptor Antagonists; Female; Humans; Male; Middle Aged; Prospective Studies; Scleroderma, Systemic; Severity of Illness Index; Skin Ulcer; Sulfonamides; Treatment Outcome | 2008 |
40 other study(ies) available for bosentan anhydrous and Skin Ulcer
| Article | Year |
|---|---|
Real-world effectiveness and safety of bosentan in Japanese patients with systemic sclerosis: A single-center retrospective study.
Topics: Bosentan; East Asian People; Humans; Retrospective Studies; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Treatment Outcome | 2023 |
Novel Use of Bosentan for Postoperative Wound Healing of the Foot in Systemic Sclerosis.
Topics: Bosentan; Humans; Scleroderma, Systemic; Skin Ulcer; Wound Healing | 2021 |
Effects of Bosentan in the Treatment of Digital Ulcers in Korean Patients With Systemic Sclerosis: A Longitudinal, Multicenter, Uncontrolled Trial.
Topics: Bosentan; Fingers; Humans; Republic of Korea; Scleroderma, Systemic; Skin Ulcer; Ulcer | 2021 |
Treatment of digital ulcers in systemic sclerosis: Case series study of thirteen patients and discussion on outcome.
Topics: Aged; Aged, 80 and over; Alprostadil; Bosentan; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Female; Fingers; Hand Dermatoses; Humans; Male; Middle Aged; Reproducibility of Results; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Time Factors; Treatment Outcome; Vasodilator Agents; Wound Healing | 2017 |
Assessment of treatment effects on digital ulcer and blood perfusion by laser speckle contrast analysis in a patient affected by systemic sclerosis.
Topics: Bosentan; Female; Fingers; Humans; Iloprost; Lasers; Methotrexate; Microcirculation; Microscopic Angioscopy; Middle Aged; para-Aminobenzoates; Raynaud Disease; Scattering, Radiation; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Tramadol; Treatment Outcome | 2017 |
Bosentan for Cutaneous Ulcers in Anti-MDA5 Dermatomyositis.
Topics: Aged; Antihypertensive Agents; Autoantibodies; Bosentan; Dermatomyositis; Female; Humans; Interferon-Induced Helicase, IFIH1; Skin Ulcer | 2018 |
Bosentan and sildenafil: successful treatment in a sclerodermic patient with refractory ulcers.
Topics: Bosentan; Endothelin Receptor Antagonists; Female; Humans; Middle Aged; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Remission Induction; Scleroderma, Systemic; Sildenafil Citrate; Skin Ulcer; Sulfonamides; Sulfones | 2013 |
In systemic sclerosis patients, bosentan is safe and effective for digital ulcer prevention and it seems to attenuate the development of pulmonary arterial hypertension.
Topics: Bosentan; Cardiovascular Agents; Dose-Response Relationship, Drug; Familial Primary Pulmonary Hypertension; Fingers; Humans; Hypertension, Pulmonary; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Treatment Outcome | 2014 |
Management of digital vasculopathy in systemic sclerosis: benefits of multiple courses of endothelin-1 receptor antagonists.
Topics: Adult; Bosentan; Endothelin Receptor Antagonists; Female; Fingers; Humans; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Vascular Diseases | 2014 |
[Digital ulcers in systemic scleroderma].
Topics: Bosentan; Fingers; Hand Dermatoses; Humans; Iloprost; Phosphodiesterase 5 Inhibitors; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Wound Healing | 2014 |
[Efficacy of bosentan in the treatment of digital ulcers secondary to thromboangiitis obliterans].
Topics: Aged; Amputation, Surgical; Arthritis, Infectious; Bosentan; Clinical Trials as Topic; Combined Modality Therapy; Endothelin Receptor Antagonists; Fingers; Gram-Negative Bacterial Infections; Hand Deformities, Acquired; Humans; Male; Middle Aged; Osteomyelitis; Remission Induction; Skin Ulcer; Sulfonamides; Sympathectomy; Thromboangiitis Obliterans; Vasodilator Agents | 2015 |
Digital Ulcers, Systemic Sclerosis Sine Scleroderma and Paraneoplastic Phenomena Responding to Bosentan Therapy.
Topics: Adenocarcinoma; Aged; Biopsy, Fine-Needle; Bosentan; Diagnosis, Differential; Endothelin Receptor Antagonists; Female; Fingers; Humans; Lung Neoplasms; Neoplasm Staging; Paraneoplastic Syndromes; Pneumonectomy; Scleroderma, Systemic; Serologic Tests; Skin Ulcer; Sulfonamides; Thoracic Surgery, Video-Assisted; Tomography, X-Ray Computed; Treatment Outcome | 2015 |
Digital ulcers in scleroderma patients: A retrospective observational study.
Topics: Adult; Bosentan; Female; Fingers; Humans; Iloprost; Leg; Male; Middle Aged; Retrospective Studies; Scleroderma, Localized; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Treatment Outcome; Wound Healing | 2016 |
[Digital ulcers in systemic sclerosis : A retrospective heath service study analysing treatment with bosentan and other vasoactive therapies].
Topics: Adult; Bosentan; Female; Fingers; Germany; Guideline Adherence; Health Care Surveys; Humans; Male; Middle Aged; Practice Guidelines as Topic; Practice Patterns, Physicians'; Retrospective Studies; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Treatment Outcome; Vasoconstrictor Agents; Young Adult | 2017 |
Bosentan for digital ulcers prevention does not worsen cardiopulmonary exercise test parameters in SSc patients with interstitial lung disease.
Topics: Adult; Bosentan; Disease Progression; Endothelin Receptor Antagonists; Exercise Test; Female; Fingers; Humans; Lung Diseases, Interstitial; Male; Middle Aged; Receptor, Endothelin A; Respiratory Function Tests; Scleroderma, Systemic; Skin Ulcer; Statistics as Topic; Sulfonamides; Treatment Outcome | 2016 |
Controlling the digital ulcerative disease in systemic sclerosis is associated with improved hand function.
Topics: Adult; Aged; Bosentan; Disability Evaluation; Endothelin Receptor Antagonists; Female; Hand; Humans; Male; Middle Aged; Prospective Studies; Quality of Life; Scleroderma, Systemic; Severity of Illness Index; Skin Ulcer; Sulfonamides; Treatment Outcome | 2017 |
Non-healing ischaemic digital ulcer in a systemic sclerosis patient: a challenging clinical case.
Topics: Administration, Intravenous; Administration, Oral; Bosentan; Botulinum Toxins, Type A; Cross-Sectional Studies; Female; Fingers; Humans; Iloprost; Middle Aged; Phosphodiesterase 5 Inhibitors; Scleroderma, Systemic; Sildenafil Citrate; Skin Ulcer; Sulfonamides; Treatment Outcome; Wound Healing | 2017 |
Successful treatment with bosentan for refractory digital ulcers in a patient with systemic lupus erythematosus.
Topics: Adult; Antihypertensive Agents; Bosentan; Female; Fingers; Humans; Lupus Erythematosus, Systemic; Skin Ulcer; Sulfonamides | 2008 |
Systemic lupus erythematosus, complicated with refractory skin ulcers, treated successfully with bosentan.
Topics: Adult; Antihypertensive Agents; Bosentan; Extremities; Female; Humans; Hypertension, Pulmonary; Lupus Erythematosus, Systemic; Skin Ulcer; Sulfonamides; Treatment Outcome | 2009 |
Bosentan for digital ulcers in patients with systemic sclerosis: a prospective 3-year followup study.
Topics: Aged; Antihypertensive Agents; Biopsy; Bosentan; Female; Fingers; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Scleroderma, Systemic; Skin; Skin Ulcer; Sulfonamides; Treatment Outcome | 2009 |
Liver impairment after concomitant administration of bosentan and clarithromycin in systemic sclerosis.
Topics: Aged; Anti-Bacterial Agents; Antihypertensive Agents; Bosentan; Chemical and Drug Induced Liver Injury; Clarithromycin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fingers; Humans; Hypertension, Pulmonary; Liver Function Tests; Middle Aged; Scleroderma, Systemic; Skin Ulcer; Sulfonamides | 2010 |
Efficacy of bosentan in digital ischemic ulcers.
Topics: Aged; Bosentan; Endothelin Receptor Antagonists; Fingers; Humans; Ischemia; Magnetic Resonance Angiography; Male; Microscopic Angioscopy; Middle Aged; Plethysmography; Skin Ulcer; Smoking Cessation; Sulfonamides; Thromboangiitis Obliterans; Treatment Outcome; Vasodilator Agents | 2010 |
A higher degree of criticism about the effectiveness of bosentan for digital ulcers in scleroderma patients, as for interstitial disease, is also necessary: comment on the article by Seibold et al.
Topics: Antihypertensive Agents; Bosentan; Endothelins; Fingers; Humans; Scleroderma, Systemic; Skin Ulcer; Sulfonamides | 2010 |
[Digital ulcers in systemic sclerosis--an interdisciplinary challenge].
Topics: Angiography; Antihypertensive Agents; Arm; Bosentan; Cooperative Behavior; CREST Syndrome; Endothelin Receptor Antagonists; Fatal Outcome; Fingers; Follow-Up Studies; Hand Dermatoses; Humans; Iloprost; Interdisciplinary Communication; Leg; Male; Middle Aged; Scleroderma, Limited; Skin Ulcer; Sulfonamides; Vasodilator Agents | 2010 |
Connective tissue diseases: Treatment of digital ulcers in systemic sclerosis.
Topics: Bosentan; Diarrhea; Endothelin Receptor Antagonists; Fingers; Hand; Humans; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Transaminases; Treatment Outcome | 2011 |
Significant attenuation of macrovascular involvement by bosentan in a patient with diffuse cutaneous systemic sclerosis with multiple digital ulcers and gangrene.
Topics: Antihypertensive Agents; Bosentan; Female; Fingers; Gangrene; Humans; Middle Aged; Regional Blood Flow; Scleroderma, Diffuse; Skin Ulcer; Sulfonamides | 2011 |
Bosentan in clinical practice for treating digital and other ischemic ulcers in Spanish patients with systemic sclerosis: IBER-DU cohort study.
Topics: Antihypertensive Agents; Bosentan; Cohort Studies; Humans; Hypertension; Ischemia; Randomized Controlled Trials as Topic; Retrospective Studies; Scleroderma, Systemic; Skin Ulcer; Spain; Sulfonamides; Treatment Outcome | 2011 |
Effect of a sequential therapy of bosentan and iloprost versus a monotherapy with bosentan in the treatment of scleroderma related digital ulcers.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Bosentan; Drug Therapy, Combination; Female; Fingers; Humans; Iloprost; Infusions, Intravenous; Male; Middle Aged; Retrospective Studies; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Time Factors; Treatment Outcome; Vasodilator Agents; Wound Healing; Young Adult | 2011 |
Effectiveness of bosentan in the treatment of ischemic lesions in a case of thromboangiitis obliterans (Buerger disease): a case report.
Topics: Adult; Bosentan; Compassionate Use Trials; Endothelin Receptor Antagonists; Female; Humans; Ischemia; Skin Ulcer; Sulfonamides; Thromboangiitis Obliterans; Vasodilator Agents | 2011 |
Combination therapy with an endothelin-1 receptor antagonist (bosentan) and a phosphodiesterase V inhibitor (sildenafil) for the management of severe digital ulcerations in systemic sclerosis.
Topics: Bosentan; Drug Therapy, Combination; Endothelin A Receptor Antagonists; Fingers; Humans; Male; Middle Aged; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Scleroderma, Systemic; Sildenafil Citrate; Skin Ulcer; Sulfonamides; Sulfones | 2011 |
Bosentan is effective against digital ulcerations and hyperkeratosis in systemic sclerosis.
Topics: Antihypertensive Agents; Bosentan; Female; Hand Dermatoses; Humans; Keratosis; Middle Aged; Raynaud Disease; Scleroderma, Systemic; Skin Ulcer; Sulfonamides | 2011 |
Bosentan for digital ulcers in patients with systemic sclerosis.
Topics: Adult; Aged; Antihypertensive Agents; Bosentan; Chemical and Drug Induced Liver Injury; Female; Hand Dermatoses; Humans; Male; Middle Aged; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Treatment Outcome; Young Adult | 2012 |
Low occurrence of digital ulcers in scleroderma patients treated with bosentan for pulmonary arterial hypertension: a retrospective case-control study.
Topics: Aged; Antihypertensive Agents; Bosentan; Case-Control Studies; Endothelin Receptor Antagonists; Familial Primary Pulmonary Hypertension; Female; Fingers; Humans; Hypertension, Pulmonary; Male; Middle Aged; Retrospective Studies; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Time Factors; Treatment Outcome; Vascular Diseases | 2013 |
Successful treatment of systemic sclerosis digital ulcers and pulmonary arterial hypertension with endothelin receptor antagonist bosentan.
Topics: Bosentan; Endothelin Receptor Antagonists; Fingers; Humans; Hypertension, Pulmonary; Ischemia; Male; Middle Aged; Scleroderma, Systemic; Skin Ulcer; Sulfonamides | 2003 |
Resolution of severe digital ulceration during a course of Bosentan therapy.
Topics: Antihypertensive Agents; Bosentan; Endothelin Receptor Antagonists; Fingers; Humans; Hypertension, Pulmonary; Male; Middle Aged; Scleroderma, Systemic; Skin Ulcer; Sulfonamides | 2005 |
[Bosentan for treatment of active digital ulcers in patients with systemic sclerosis].
Topics: Adult; Aged; Antibodies, Antinuclear; Bosentan; Endothelin-1; Female; Fingers; Follow-Up Studies; Humans; Ischemia; Male; Middle Aged; Raynaud Disease; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Time Factors; Treatment Outcome | 2006 |
Successful treatment of systemic sclerosis-related digital ulcers and sarcoidosis with endothelin receptor antagonist (bosentan) therapy.
Topics: Bosentan; Endothelin Receptor Antagonists; Female; Fingers; Humans; Middle Aged; Sarcoidosis, Pulmonary; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Tomography, X-Ray Computed | 2006 |
Efficacy of bosentan in treatment of unresponsive cutaneous ulceration in disabling pansclerotic morphea in children.
Topics: Antihypertensive Agents; Bosentan; Child, Preschool; Contracture; Disabled Children; Female; Humans; Scleroderma, Localized; Skin Ulcer; Sulfonamides; Treatment Outcome | 2006 |
Bosentan as a rescue therapy in scleroderma refractory digital ulcers.
Topics: Adult; Antihypertensive Agents; Bosentan; Endothelin Receptor Antagonists; Female; Fingers; Humans; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Treatment Outcome | 2007 |
[Digital ulcers in systemic sclerosis].
Topics: Bosentan; Fingers; Humans; Iloprost; Scleroderma, Systemic; Skin Ulcer; Sulfonamides; Vasodilator Agents | 2008 |