bosentan anhydrous has been researched along with Liver Dysfunction in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hashimoto, Y; Horiuchi, I; Ichida, F; Miyawaki, T; Mori, YI; Taguchi, M | 1 |
| Cafferty, FH; Hodgkins, D; Hughes, RJ; Pepke-Zaba, J; Suntharalingam, J | 1 |
| Austin, MJ; Callender, ME; Heneghan, MA; Knisely, AS; McDougall, NI; O'Grady, JG; Rela, M; Sizer, E; Wendon, JA; Wilson, C | 1 |
| Bauer, C; Diekmann, F; Hocher, B; Lutz, J; Slowinski, T; Thöne-Reineke, C; Zart, R | 1 |
1 trial(s) available for bosentan anhydrous and Liver Dysfunction
| Article | Year |
|---|---|
Does rapid dose titration affect the hepatic safety profile of Bosentan?
Topics: Alanine Transaminase; Antihypertensive Agents; Bosentan; Connective Tissue Diseases; Drug Administration Schedule; Female; Humans; Hypertension, Pulmonary; Incidence; Liver Diseases; Liver Function Tests; Male; Middle Aged; Risk Factors; Sex Factors; Sulfonamides; Treatment Outcome | 2006 |
3 other study(ies) available for bosentan anhydrous and Liver Dysfunction
| Article | Year |
|---|---|
Mechanisms responsible for the altered pharmacokinetics of bosentan: analysis utilizing rats with bile duct ligation-induced liver dysfunction.
Topics: Animals; Bile Ducts; Bosentan; Cytochrome P-450 Enzyme System; Ligation; Liver Diseases; Male; Rats; Rats, Wistar; Sulfonamides | 2009 |
Safety and efficacy of combined use of sildenafil, bosentan, and iloprost before and after liver transplantation in severe portopulmonary hypertension.
Topics: Adult; Blood Pressure; Bosentan; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Humans; Hypertension, Portal; Hypertension, Pulmonary; Iloprost; Liver Diseases; Liver Transplantation; Male; Piperazines; Pulmonary Artery; Purines; Severity of Illness Index; Sildenafil Citrate; Sulfonamides; Sulfones; Treatment Outcome; Vasodilator Agents | 2008 |
Role of the paracrine liver endothelin system in the pathogenesis of CCl4-induced liver injury.
Topics: Animals; Bosentan; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Endothelin Receptor Antagonists; Endothelins; Liver; Liver Diseases; Liver Function Tests; Male; Rats; Rats, Inbred WKY; Sulfonamides | 1995 |