Page last updated: 2024-08-26

bosentan anhydrous and Chronic Disease

bosentan anhydrous has been researched along with Chronic Disease in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (14.29)18.2507
2000's23 (54.76)29.6817
2010's12 (28.57)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Kelder, JC; Mager, JJ; Post, MC; Snijder, RJ; Ten Klooster, L; van Thor, MCJ1
Halank, M; Held, M; Igarashi, T; Kunihara, T; Nomura, R; Sata, F; Schäfers, HJ; Wilkens, H1
Caspi, A; DeMets, D; Kiowski, W; Kobrin, I; Krum, H; Massie, BM; McMurray, JJV; Packer, M; Petrie, MC; Pratt, CM; Roux, S; Swedberg, K1
Gaine, SP; Murphy, DM; Murphy, DT; Murray, JG1
Cannon, JE; Pepke-Zaba, J1
Kario, K; Nishikawa-Takahashi, M; Ueno, S1
Cebotari, S; Hoeper, MM; Madani, MM; Meyer, B; Nakanishi, N; Rubin, LJ1
Lejnieks, A; Lesina, K; Rudzitis, A; Sablinskis, K; Skride, A1
Channick, R; Jais, X; Pepke-Zaba, J1
Gewitz, M; Krishnan, S; Krishnan, U1
Arora, R; Jawad, E1
D'Armini, AM; Delcroix, M; Ghofrani, HA; Hoeper, MM; Jaïs, X; Jansa, P; Lang, IM; Mayer, E; Morganti, A; Pepke-Zaba, J; Perchenet, L; Rubin, LJ; Simonneau, G; Torbicki, A1
Cassandro, R; Confalonieri, M; Harari, S; Kodric, M; Piattella, M; Potena, A; Scarda, A; Scarduelli, C; Vassallo, FG1
Kostrubiec, M; Pedowska-Włoszek, J; Pruszczyk, P1
Confalonieri, M; Kodric, M; Longo, C; Vassallo, FG1
Agnelli, G; Becattini, C; Busti, C; Gennarini, S; Manina, G1
Kähler, CM1
Bauleo, C; Catapano, G; Formichi, B; Genovesi, D; Giuntini, C; Mannucci, F; Marini, C; Michelassi, C; Monti, S; Prediletto, R1
Aoki, T; Fukumoto, Y; Miura, Y; Miyamichi-Yamamoto, S; Nochioka, K; Satoh, K; Shimokawa, H; Sugimura, K; Tatebe, S1
Dinger, B; Fidone, S; He, L; Liu, X; Stensaas, L1
Goto, K; Miyauchi, T1
Piuhola, J; Ruskoaho, H; Szokodi, I1
Chin, KM; Kim, NH; Rubin, LJ1
Apostolopoulou, SC; Cokkinos, DV; Manginas, A; Rammos, S1
Del Rio, R; Iturriaga, R; Rey, S1
Hammerschmidt, S; Pankau, H; Seyfarth, HJ; Winkler, J; Wirtz, H1
Christopoulos, A; Kourouklis, S; Kyriakides, ZS; Liagkas, K; Paradellis, G1
Casset-Sedon, D; Cosnay, P; Maillot, F; Pierre, B; Regina, S; Sitbon, O1
Alonso-Pulpón Rivera, L; Gómez Bueno, M; González González, M; Moñivas Palomero, V; Ortiz Uribe, JC; Segovia Cubero, J1
Auger, WR; Fedullo, PF; Kerr, KM; Kim, NH; Test, VJ1
Brentjens, TE; Bulman, W; Coyle, CM; Dickstein, ML; Emond, J; Horn, EM; Kawut, SM; Wilt, JS1
Aubert, JD; Domenighetti, G; Fischler, M; Geiser, T; Huber, L; Rochat, T; Speich, R; Treder, U; Ulrich, S1
Adnot, S; Clozel, M; Eddahibi, S; Levame, M; Raffestin, B1
Clozel, JP; Clozel, M; Hess, P; Löffler, BM; Maire, JP; Teerlink, JR1
Bertel, O; Kiowski, W; Sütsch, G1
Comoy, E; Compagnon, P; Derumeaux, G; Henry, JP; Hogie, M; Lallemand, F; Letac, B; Macé, B; Mulder, P; Richard, V; Thuillez, C1
Abbott, BM; Bertelsen, DL; DeSiato, MA; Rumsey, WL1
Bertel, O; Christen, S; Hunziker, P; Kim, JH; Kiowski, W; Rickenbacher, P; Strobel, W; Sütsch, G; Yan, XW1
Channick, RN; Chiles, PG; Kim, H; Konopka, RG; Marsh, JJ; Morris, TA; Pedersen, CA; Yung, GL1
Abraham, WT; Lamba, S; Suresh, DP1
Bertel, O; Kiowski, W; Oechslin, E; Sütsch, G1
Cheng, TO1

Reviews

13 review(s) available for bosentan anhydrous and Chronic Disease

ArticleYear
Long-Term Effect of Endothelin Receptor Antagonism With Bosentan on the Morbidity and Mortality of Patients With Severe Chronic Heart Failure: Primary Results of the ENABLE Trials.
    JACC. Heart failure, 2017, Volume: 5, Issue:5

    Topics: Aged; Australia; Bosentan; Cause of Death; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Endothelin Receptor Antagonists; Europe; Female; Heart Failure; Humans; Internationality; Kaplan-Meier Estimate; Male; Middle Aged; Morbidity; North America; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Risk Assessment; Severity of Illness Index; Sulfonamides; Survival Analysis; Time Factors; Treatment Outcome

2017
Is distal chronic thromboembolic pulmonary hypertension treatable with PAH targeted drugs?
    Seminars in respiratory and critical care medicine, 2013, Volume: 34, Issue:5

    Topics: Antihypertensive Agents; Bosentan; Chronic Disease; Compassionate Use Trials; Endarterectomy; Humans; Hypertension, Pulmonary; Piperazines; Pulmonary Embolism; Purines; Pyrazoles; Pyrimidines; Sildenafil Citrate; Sulfonamides; Sulfones; Treatment Outcome

2013
Chronic thromboembolic pulmonary hypertension.
    The Lancet. Respiratory medicine, 2014, Volume: 2, Issue:7

    Topics: Angioplasty, Balloon; Bosentan; Chronic Disease; Endarterectomy; Endothelin Receptor Antagonists; Enzyme Activators; Humans; Hypertension, Pulmonary; Phosphodiesterase 5 Inhibitors; Piperazines; Pulmonary Embolism; Purines; Pyrazoles; Pyrimidines; Sildenafil Citrate; Sulfonamides; Thromboembolism

2014
Medical Therapy in Chronic Thromboembolic Pulmonary Hypertension.
    Annals of the American Thoracic Society, 2016, Volume: 13 Suppl 3

    Topics: Bosentan; Chronic Disease; Comorbidity; Endarterectomy; Endothelin Receptor Antagonists; Humans; Hypertension, Pulmonary; Pulmonary Embolism; Pyrazoles; Pyrimidines; Randomized Controlled Trials as Topic; Recurrence; Secondary Prevention; Sulfonamides

2016
Chronic stable angina pectoris.
    Disease-a-month : DM, 2008, Volume: 54, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetanilides; Angina Pectoris; Antihypertensive Agents; Benzazepines; Bosentan; Chronic Disease; Counterpulsation; Cyclic Nucleotide-Gated Cation Channels; Exercise Test; Heart Murmurs; Humans; Ivabradine; Myocardial Contraction; Myocardial Ischemia; Myocardial Revascularization; Myocardium; Nicorandil; Oxygen Consumption; Perhexiline; Piperazines; Protein Kinase Inhibitors; Ranolazine; Sulfonamides; Trimetazidine; Vasodilator Agents

2008
[Potential role of endothelin in patients with acute pulmonary embolism and chronic thromboembolic pulmonary hypertension].
    Pneumonologia i alergologia polska, 2009, Volume: 77, Issue:2

    Topics: Acute Disease; Antihypertensive Agents; Bosentan; Chronic Disease; Endothelins; Humans; Hypertension, Pulmonary; Pulmonary Embolism; Sulfonamides

2009
Bosentan for chronic thromboembolic pulmonary hypertension.
    Expert review of cardiovascular therapy, 2009, Volume: 7, Issue:12

    Topics: Antihypertensive Agents; Bosentan; Chronic Disease; Endothelin Receptor Antagonists; Humans; Hypertension, Pulmonary; Sulfonamides; Thromboembolism

2009
Bosentan for chronic thromboembolic pulmonary hypertension: findings from a systematic review and meta-analysis.
    Thrombosis research, 2010, Volume: 126, Issue:1

    Topics: Antihypertensive Agents; Bosentan; Case-Control Studies; Chronic Disease; Cohort Studies; Double-Blind Method; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Pulmonary Embolism; Randomized Controlled Trials as Topic; Sulfonamides; Treatment Outcome; Vascular Resistance

2010
[New expansion of endothelin research: perspectives for clinical application of endothelin-receptor antagonists].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2003, Volume: 121, Issue:2

    Topics: Animals; Bosentan; Cardiovascular Diseases; Chronic Disease; Clinical Trials as Topic; Disease Models, Animal; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; Growth Substances; Humans; Mitogens; Receptors, Endothelin; Sulfonamides; Vasoconstriction

2003
The right ventricle in pulmonary hypertension.
    Coronary artery disease, 2005, Volume: 16, Issue:1

    Topics: Bosentan; Cardiac Output; Chronic Disease; Drug Therapy, Combination; Epoprostenol; Female; Heart Failure; Heart Function Tests; Heart Ventricles; Humans; Hypertension, Pulmonary; Male; Prognosis; Risk Assessment; Severity of Illness Index; Stroke Volume; Sulfonamides; Survival Rate; Treatment Outcome; Ventricular Dysfunction, Right; Ventricular Function

2005
Chronic thromboembolic pulmonary hypertension.
    Clinics in chest medicine, 2007, Volume: 28, Issue:1

    Topics: Antibodies, Antiphospholipid; Bosentan; Cardiac Catheterization; Chronic Disease; Endarterectomy; Endothelin Receptor Antagonists; Humans; Hypertension, Pulmonary; Physical Exertion; Pulmonary Embolism; Risk Factors; Sulfonamides; Thrombectomy

2007
New developments in heart failure: role of endothelin and the use of endothelin receptor antagonists.
    Journal of cardiac failure, 2000, Volume: 6, Issue:4

    Topics: Bosentan; Carboxylic Acids; Chronic Disease; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Humans; Indans; Peptides, Cyclic; Prognosis; Pyridines; Pyrimidines; Receptors, Endothelin; Sulfonamides; Treatment Outcome

2000
Hemodynamic effects of bosentan in patients with chronic heart failure.
    Heart failure reviews, 2001, Volume: 6, Issue:4

    Topics: Bosentan; Chronic Disease; Clinical Trials as Topic; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Hemodynamics; Humans; Receptors, Endothelin; Sulfonamides

2001

Trials

8 trial(s) available for bosentan anhydrous and Chronic Disease

ArticleYear
Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFiT (Bosentan Effects in iNopErable Forms of chronIc Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial.
    Journal of the American College of Cardiology, 2008, Dec-16, Volume: 52, Issue:25

    Topics: Antihypertensive Agents; Bosentan; Chronic Disease; Disease Progression; Double-Blind Method; Endarterectomy; Endothelin Receptor Antagonists; Exercise Tolerance; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged; Prognosis; Severity of Illness Index; Sulfonamides; Thromboembolism

2008
Bosentan for patients with chronic thromboembolic pulmonary hypertension.
    European journal of internal medicine, 2009, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antihypertensive Agents; Bosentan; Chronic Disease; Diuretics; Drug Therapy, Combination; Dyspnea; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Prospective Studies; Pulmonary Embolism; Sulfonamides; Treatment Outcome; Walking; Young Adult

2009
Percutaneous transluminal pulmonary angioplasty markedly improves pulmonary hemodynamics and long-term prognosis in patients with chronic thromboembolic pulmonary hypertension.
    Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:2

    Topics: Aged; Angioplasty; Antihypertensive Agents; Bosentan; Chronic Disease; Combined Modality Therapy; Epoprostenol; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Piperazines; Prognosis; Prospective Studies; Pulmonary Circulation; Purines; Sildenafil Citrate; Sulfonamides; Sulfones; Treatment Outcome; Vasodilator Agents

2012
Effect of the oral endothelin antagonist bosentan on the clinical, exercise, and haemodynamic status of patients with pulmonary arterial hypertension related to congenital heart disease.
    Heart (British Cardiac Society), 2005, Volume: 91, Issue:11

    Topics: Administration, Oral; Adult; Antihypertensive Agents; Bosentan; Chronic Disease; Exercise; Exercise Tolerance; Female; Heart Defects, Congenital; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Oximetry; Sulfonamides; Treatment Outcome

2005
[Role of bosentan in patients with chronic venous thromboembolic pulmonary hypertension].
    Medicina clinica, 2007, Jan-13, Volume: 128, Issue:1

    Topics: Administration, Oral; Antihypertensive Agents; Bosentan; Chronic Disease; Data Interpretation, Statistical; Female; Follow-Up Studies; Humans; Hypertension, Pulmonary; Male; Middle Aged; Pulmonary Embolism; Retrospective Studies; Sulfonamides; Time Factors; Treatment Outcome

2007
Bosentan therapy for chronic thromboembolic pulmonary hypertension. A national open label study assessing the effect of Bosentan on haemodynamics, exercise capacity, quality of life, safety and tolerability in patients with chronic thromboembolic pulmonar
    Swiss medical weekly, 2007, Oct-20, Volume: 137, Issue:41-42

    Topics: Aged; Antihypertensive Agents; Bosentan; Chronic Disease; Endothelin Receptor Antagonists; Exercise Tolerance; Female; Health Status Indicators; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Pulmonary Embolism; Quality of Life; Severity of Illness Index; Sulfonamides

2007
Acute and short-term effects of the nonpeptide endothelin-1 receptor antagonist bosentan in humans.
    Cardiovascular drugs and therapy, 1997, Volume: 10, Issue:6

    Topics: Administration, Oral; Adult; Aged; Blood Pressure; Bosentan; Chronic Disease; Double-Blind Method; Endothelin Receptor Antagonists; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Receptor, Endothelin A; Sulfonamides; Time Factors; Vascular Resistance

1997
Short-term oral endothelin-receptor antagonist therapy in conventionally treated patients with symptomatic severe chronic heart failure.
    Circulation, 1998, Nov-24, Volume: 98, Issue:21

    Topics: Administration, Oral; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Bosentan; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Endothelin Receptor Antagonists; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Prospective Studies; Receptor, Endothelin A; Sulfonamides; Treatment Outcome

1998

Other Studies

21 other study(ies) available for bosentan anhydrous and Chronic Disease

ArticleYear
Bosentan or Macitentan Therapy in Chronic Thromboembolic Pulmonary Hypertension?
    Lung, 2019, Volume: 197, Issue:6

    Topics: Aged; Bosentan; Chronic Disease; Drug Therapy, Combination; Endarterectomy; Endothelin Receptor Antagonists; Enzyme Activators; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Phosphodiesterase 5 Inhibitors; Pulmonary Embolism; Pyrazoles; Pyrimidines; Retrospective Studies; Sildenafil Citrate; Sulfonamides; Survival Rate; Walk Test

2019
Haemodynamic benefit of bridging use of bosentan prior to pulmonary endarterectomy.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2021, 10-22, Volume: 60, Issue:4

    Topics: Bosentan; Chronic Disease; Endarterectomy; Hemodynamics; Humans; Hypertension, Pulmonary; Pulmonary Artery; Pulmonary Embolism; Treatment Outcome

2021
Case 1: chronic thromboembolic pulmonary hypertension (CTEPH).
    Irish medical journal, 2013, Volume: 106, Issue:5

    Topics: Adult; Anticoagulants; Antihypertensive Agents; Bosentan; Chronic Disease; Diuretics; Drug Therapy, Combination; Humans; Hypertension, Pulmonary; Male; Pulmonary Embolism; Sulfonamides; Tomography, X-Ray Computed; Warfarin

2013
Long-term advanced therapy with bosentan improves symptoms and prevents deterioration of inoperable chronic thromboembolic pulmonary hypertension.
    Life sciences, 2014, Nov-24, Volume: 118, Issue:2

    Topics: Asian People; Bosentan; Chronic Disease; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Japan; Male; Middle Aged; Pulmonary Embolism; Sulfonamides; Time Factors

2014
First data from Latvian chronic thromboembolic pulmonary hypertension registry.
    European journal of internal medicine, 2016, Volume: 32

    Topics: Adult; Age Distribution; Aged; Anticoagulants; Bosentan; Chronic Disease; Female; Humans; Hypertension, Pulmonary; Incidence; Latvia; Male; Middle Aged; Phenylpropionates; Prevalence; Pulmonary Embolism; Pyrazoles; Pyridazines; Pyridones; Registries; Rivaroxaban; Sex Distribution; Sildenafil Citrate; Sulfonamides; Vasodilator Agents; Warfarin; Young Adult

2016
Treatment of pulmonary hypertension in children with chronic lung disease with newer oral therapies.
    Pediatric cardiology, 2008, Volume: 29, Issue:6

    Topics: Administration, Oral; Antihypertensive Agents; Bosentan; Bronchopulmonary Dysplasia; Cardiac Catheterization; Child; Child, Preschool; Chronic Disease; Female; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Male; Piperazines; Purines; Sildenafil Citrate; Sulfonamides; Sulfones; Vasodilator Agents

2008
Chronic thromboembolic pulmonary hypertension as a cause of dyspnoea in an older patient with a complex history.
    European respiratory review : an official journal of the European Respiratory Society, 2009, Volume: 18, Issue:113

    Topics: Antihypertensive Agents; Bosentan; Chronic Disease; Dyspnea; Endarterectomy; Humans; Hypertension, Pulmonary; Male; Middle Aged; Pulmonary Embolism; Sulfonamides; Tomography, Spiral Computed

2009
Improved survival in patients with inoperable chronic thromboembolic pulmonary hypertension.
    Internal and emergency medicine, 2013, Volume: 8, Issue:4

    Topics: Acid-Base Equilibrium; Aged; Antihypertensive Agents; Blood Gas Analysis; Bosentan; Cardiac Output; Chronic Disease; Drug Therapy, Combination; Exercise Test; Female; Humans; Hypertension, Pulmonary; Isoxazoles; Male; Middle Aged; Oxygen Consumption; Oxygen Inhalation Therapy; Piperazines; Purines; Severity of Illness Index; Sildenafil Citrate; Sulfonamides; Sulfones; Survival Rate; Thiophenes; Thromboembolism; Treatment Outcome; Vascular Resistance; Vasodilator Agents

2013
Effect of endothelin receptor antagonist bosentan on chronic hypoxia-induced inflammation and chemoafferent neuron adaptation in rat carotid body.
    High altitude medicine & biology, 2012, Volume: 13, Issue:3

    Topics: Acid Sensing Ion Channels; Adaptation, Physiological; Animals; Antihypertensive Agents; Bosentan; Carotid Body; Cell Movement; Chemokine CCL2; Chemoreceptor Cells; Chronic Disease; Endothelin-1; Gene Expression; Hypoxia; Inflammation; Interleukin-1; Interleukin-1beta; Leukocyte Common Antigens; Macrophages; Rats; Receptor, Endothelin A; Sulfonamides; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase

2012
Endothelin receptor blockade and exacerbation of heart failure.
    Circulation, 2003, Jun-10, Volume: 107, Issue:22

    Topics: Animals; Bosentan; Chronic Disease; Clinical Trials as Topic; Endothelin Receptor Antagonists; Endothelins; Heart; Heart Failure; Humans; Myocardial Contraction; Phenylpropionates; Pyrimidines; Rats; Receptor, Endothelin A; Sulfonamides; Vascular Resistance; Water-Electrolyte Balance

2003
Role of endothelin-1 on the enhanced carotid body activity induced by chronic intermittent hypoxia.
    Advances in experimental medicine and biology, 2006, Volume: 580

    Topics: Animals; Bosentan; Carotid Body; Cats; Chronic Disease; Electrophysiology; Endothelin Receptor Antagonists; Endothelin-1; Hypoxia; Immunohistochemistry; In Vitro Techniques; Male; Sulfonamides

2006
Long-term bosentan in chronic thromboembolic pulmonary hypertension.
    Respiration; international review of thoracic diseases, 2007, Volume: 74, Issue:3

    Topics: Antihypertensive Agents; Bosentan; Chronic Disease; Exercise Tolerance; Female; Follow-Up Studies; Humans; Hypertension, Pulmonary; Kaplan-Meier Estimate; Male; Prospective Studies; Sulfonamides; Thromboembolism; Treatment Outcome; Ventricular Function, Right

2007
Bosentan in Eisenmenger syndrome and chronic thromboembolic pulmonary hypertension.
    European journal of clinical investigation, 2006, Volume: 36 Suppl 3

    Topics: Administration, Oral; Adult; Antihypertensive Agents; Bosentan; Chronic Disease; Down Syndrome; Echocardiography, Doppler; Eisenmenger Complex; Endothelin Receptor Antagonists; Female; Humans; Male; Middle Aged; Pulmonary Embolism; Sulfonamides; Treatment Outcome

2006
[Chronic pulmonary thromboembolism revealing beta-thalassemia intermedia after splenectomy].
    La Revue de medecine interne, 2006, Volume: 27, Issue:12

    Topics: Antihypertensive Agents; beta-Thalassemia; Bosentan; Chronic Disease; Humans; Iron Overload; Male; Middle Aged; Pulmonary Embolism; Splenectomy; Sulfonamides; Treatment Outcome

2006
Severe pulmonary hypertension due to chronic echinococcal pulmonary emboli treated with targeted pulmonary vascular therapy and hepatic resection.
    Chest, 2007, Volume: 132, Issue:4

    Topics: Adult; Antihypertensive Agents; Bosentan; Chronic Disease; Echinococcosis, Hepatic; Echinococcosis, Pulmonary; Epoprostenol; Hepatectomy; Humans; Hypertension, Pulmonary; Male; Pulmonary Artery; Pulmonary Embolism; Sulfonamides; Thoracic Surgery, Video-Assisted; Vena Cava, Inferior

2007
Protection from pulmonary hypertension with an orally active endothelin receptor antagonist in hypoxic rats.
    The American journal of physiology, 1995, Volume: 268, Issue:2 Pt 2

    Topics: Animals; Bosentan; Chronic Disease; Endothelin Receptor Antagonists; Endothelins; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Male; Rats; Rats, Wistar; Sulfonamides

1995
Role of endothelin in the maintenance of blood pressure in conscious rats with chronic heart failure. Acute effects of the endothelin receptor antagonist Ro 47-0203 (bosentan).
    Circulation, 1994, Volume: 90, Issue:5

    Topics: Animals; Blood Pressure; Bosentan; Chronic Disease; Cilazapril; Endothelin Receptor Antagonists; Endothelins; Heart Failure; Male; Rats; Rats, Wistar; Sulfonamides

1994
Role of endogenous endothelin in chronic heart failure: effect of long-term treatment with an endothelin antagonist on survival, hemodynamics, and cardiac remodeling.
    Circulation, 1997, Sep-16, Volume: 96, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Bosentan; Cardiac Volume; Chronic Disease; Collagen; Consciousness; Coronary Vessels; Cyclic GMP; Echocardiography; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Heart Failure; Heart Ventricles; Male; Myocardial Infarction; Myocardium; Norepinephrine; Pressure; Protein Precursors; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Sulfonamides; Survival Analysis; Ventricular Function, Left

1997
Nitric oxide and endothelin in acute hypoxic pulmonary vasoconstriction and adaptation to chronic hypoxia.
    Advances in experimental medicine and biology, 1997, Volume: 428

    Topics: Acclimatization; Acute Disease; Animals; Antihypertensive Agents; Blood Pressure; Bosentan; Chronic Disease; Endothelium, Vascular; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sulfonamides; Vasoconstriction

1997
Endothelin mediates pulmonary vascular remodelling in a canine model of chronic embolic pulmonary hypertension.
    The European respiratory journal, 2000, Volume: 15, Issue:4

    Topics: Analysis of Variance; Animals; Antihypertensive Agents; Bosentan; Chronic Disease; Culture Techniques; Disease Models, Animal; Dogs; Endothelin-1; Female; Hemodynamics; Hypertension, Pulmonary; Immunohistochemistry; Lung; Male; Probability; Pulmonary Artery; Pulmonary Circulation; Pulmonary Embolism; Reference Values; Sulfonamides; Tomography, Emission-Computed; Vascular Resistance

2000
Endothelin receptor blockade in congestive heart failure.
    Circulation, 2001, Oct-30, Volume: 104, Issue:18

    Topics: Acute Disease; Antihypertensive Agents; Bosentan; Chronic Disease; Clinical Trials as Topic; Endothelin Receptor Antagonists; Endothelin-1; Exercise Tolerance; Heart Failure; Hemodynamics; Humans; Phenylpropionates; Pyridines; Pyrimidines; Sulfonamides; Tetrazoles; Treatment Outcome; Vasodilator Agents

2001