bosentan anhydrous has been researched along with Body Weight in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (44.44) | 18.2507 |
| 2000's | 9 (33.33) | 29.6817 |
| 2010's | 5 (18.52) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Li, G; Xu, X; Zhao, Z | 1 |
| Ferguson-Sells, L; Li, B; Small, D; Velez de Mendizabal, N | 1 |
| Hirono, K; Ichida, F; Nakamura, S; Ozawa, S; Taguchi, M; Watanabe, N; Yoshimura, N | 1 |
| Beghetti, M; Dingemanse, J; Géhin, M; Krause, A; Kusic-Pajic, A; Zisowsky, J | 1 |
| Ajisaka, R; Jesmin, S; Maeda, S; Miyauchi, T; Otsuki, T; Shimojo, N; Sugawara, J; Tanaka, H; Yoshizawa, M | 1 |
| Hadi, AM; Mouchaers, KT; Postmus, PE; Schalij, I; van der Laarse, WJ; van Hinsbergh, VW; van Nieuw Amerongen, GP; Versteilen, AM; Vonk-Noordegraaf, A | 1 |
| Ergul, A; Kelly-Cobbs, AI; Portik-Dobos, V; Sachidanandam, K | 1 |
| Akita, C; Hashimoto, Y; Hirono, K; Horiuchi, I; Ichida, F; Kato, Y; Miyawaki, T; Nakamura, T; Nakayama, T; Saji, T; Taguchi, M; Yoshimura, N | 1 |
| Barst, RJ; Bingaman, D; Dingemanse, J; Doran, A; Gaitonde, M; Ivy, D; Nguyen, N; Schmitt, K; van Giersbergen, PL; Widlitz, A | 1 |
| Bäcker, A; Cervenka, L; Kramer, HJ; Opocensky, M; Vanêcková, I; Vernerová, Z | 1 |
| Bäcker, A; Cervenka, L; Dvorák, P; Eis, V; Kramer, HJ; Opocenský, M; Schejbalová, S; Vanecková, I; Vernerová, Z | 1 |
| Nathan, T; Rose, T; Simoni, J; Tran, RM; Wesson, DE | 1 |
| Ding, Y; Judd, RL; Zhong, J; Zou, R | 1 |
| Larivière, R; Schiffrin, EL; Sventek, P; Thibault, G | 1 |
| Li, JS; Schiffrin, EL | 2 |
| Stevens, EJ; Tomlinson, DR | 1 |
| Boheler, KR; Firth, JD; Kaddoura, S; Poole-Wilson, PA; Sugden, PH | 1 |
| Garcia, R; Knafo, L; Li, JS; Schiffrin, EL; Turgeon, A | 1 |
| Bruneval, P; Clozel, JP; Clozel, M; Gonzales, MF; Heudes, D; Karam, H; Löffler, BM | 1 |
| Ercan, ZS; Hodoglugil, U; Sipahi, E; Türker, RK | 1 |
| Clozel, M; Gerbes, AL; Reichen, J; Sägesser, H; Steiner, MJ | 1 |
| Fraser, TB; Mangos, GJ; Turner, SW; Whitworth, JA | 1 |
| Gedikoglu, G; Guc, MO; Iskit, AB; Sungur, A | 1 |
| Bellini, G; Bernobich, E; Cosenzi, A; Plazzotta, N; Seculin, P | 1 |
| Belabbas, H; Herizi, A; Jover, B; Mimran, A | 1 |
| Ficai, S; Herizi, A; Jover, B; Mimran, A | 1 |
3 trial(s) available for bosentan anhydrous and Body Weight
| Article | Year |
|---|---|
Population Pharmacokinetics of Tadalafil in Pediatric Patients with Pulmonary Arterial Hypertension: A Combined Adult/Pediatric Model.
Topics: Adult; Area Under Curve; Body Weight; Bosentan; Child; Female; Humans; Male; Pulmonary Arterial Hypertension; Tadalafil | 2022 |
Involvement of endothelin-1 in habitual exercise-induced increase in arterial compliance.
Topics: Adipose Tissue; Aged; Antihypertensive Agents; Arteries; Blood Glucose; Blood Pressure; Body Weight; Bosentan; Carotid Arteries; Cholesterol; Compliance; Endothelin Receptor Antagonists; Endothelin-1; Exercise; Female; Heart Rate; Humans; Male; Middle Aged; Sulfonamides | 2009 |
Pharmacokinetics, safety, and efficacy of bosentan in pediatric patients with pulmonary arterial hypertension.
Topics: Adolescent; Analysis of Variance; Antihypertensive Agents; Body Weight; Bosentan; Child; Child, Preschool; Drug Administration Schedule; Female; Half-Life; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Sulfonamides | 2003 |
24 other study(ies) available for bosentan anhydrous and Body Weight
| Article | Year |
|---|---|
The Protective Effect of Bosentan against Atherosclerosis in Apolipoprotein E-Deficient Mice Is Mediated by miRNA-21.
Topics: Animals; Aorta, Thoracic; Apolipoproteins E; Apoptosis Regulatory Proteins; Atherosclerosis; bcl-2-Associated X Protein; Body Weight; Bosentan; Caspase 3; Diet, High-Fat; Lipids; Mice; Mice, Inbred C57BL; MicroRNAs; Protective Agents; RNA-Binding Proteins; RNA, Messenger | 2019 |
A model analysis for dose-response relationship of warfarin in Japanese children: An introduction of the SIZE parameter.
Topics: Adolescent; Anticoagulants; Body Weight; Bosentan; Child; Child, Preschool; Cytochrome P450 Family 4; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Genotype; Humans; Japan; Longitudinal Studies; Male; Models, Biological; Retrospective Studies; Sulfonamides; Vitamin K Epoxide Reductases; Warfarin | 2016 |
Pediatric Development of Bosentan Facilitated by Modeling and Simulation.
Topics: Adult; Body Weight; Bosentan; Child; Humans; Hypertension, Pulmonary; Models, Biological; Pediatrics; Sulfonamides | 2017 |
Endothelin receptor blockade combined with phosphodiesterase-5 inhibition increases right ventricular mitochondrial capacity in pulmonary arterial hypertension.
Topics: Animals; Body Weight; Bosentan; Capillaries; Cyclic GMP-Dependent Protein Kinases; Diffusion; Endothelin Receptor Antagonists; Fibrosis; Hemodynamics; Hypertension, Pulmonary; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Myoglobin; Organ Size; Oxygen Consumption; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Pulmonary Artery; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfonamides; Sulfones; Ultrasonography | 2009 |
Dual endothelin receptor antagonism prevents remodeling of resistance arteries in diabetes.
Topics: Animals; Blood Glucose; Body Weight; Bosentan; Collagen Type I; Diabetes Mellitus, Type 2; Endothelin Receptor Antagonists; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Mesenteric Arteries; Rats; Rats, Inbred Strains; Rats, Wistar; Sulfonamides; Tunica Media | 2010 |
Pharmacokinetics of bosentan in routinely treated Japanese pediatric patients with pulmonary arterial hypertension.
Topics: Adolescent; Age Factors; Aryl Hydrocarbon Hydroxylases; Asian People; Bayes Theorem; Body Weight; Bosentan; Child; Child, Preschool; Computer Simulation; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Drug Interactions; Familial Primary Pulmonary Hypertension; Female; Genotype; Heart Failure; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Liver-Specific Organic Anion Transporter 1; Male; Models, Biological; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Piperazines; Polymorphism, Single Nucleotide; Purines; Sildenafil Citrate; Solute Carrier Organic Anion Transporter Family Member 1B3; Sulfonamides; Sulfones | 2011 |
Early endothelin-A receptor blockade decreases blood pressure and ameliorates end-organ damage in homozygous Ren-2 rats.
Topics: Animals; Animals, Genetically Modified; Atrasentan; Blood Pressure; Body Weight; Bosentan; Cardiomegaly; Endothelin A Receptor Antagonists; Endothelin-1; Glomerulosclerosis, Focal Segmental; Heart Ventricles; Hypertension; Kidney; Male; Myocardium; Organ Size; Osmolar Concentration; Proteinuria; Pyrrolidines; Rats; Rats, Sprague-Dawley; Renin; Sodium Chloride, Dietary; Sulfonamides; Survival Analysis | 2005 |
Early-onset endothelin receptor blockade in hypertensive heterozygous Ren-2 rats.
Topics: Animals; Animals, Genetically Modified; Antihypertensive Agents; Atrasentan; Blood Pressure; Body Weight; Bosentan; Cardiomegaly; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin Receptor Antagonists; Endothelin-1; Glomerulosclerosis, Focal Segmental; Heterozygote; Hypertension; Male; Proteinuria; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Renin; Sodium Chloride, Dietary; Sulfonamides; Time Factors | 2006 |
Dietary protein induces endothelin-mediated kidney injury through enhanced intrinsic acid production.
Topics: Acidosis, Renal Tubular; Acids; Animals; Bicarbonates; Body Weight; Bosentan; Caseins; Dietary Proteins; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Male; Phenylpropionates; Pyrimidines; Rats; Rats, Inbred Strains; Receptor, Endothelin A; Receptor, Endothelin B; Sulfonamides | 2007 |
Endothelin-1 receptor blockade prevented the electrophysiological dysfunction in cardiac myocytes of streptozotocin-induced diabetic rats.
Topics: Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Body Weight; Bosentan; Calcium Channels, L-Type; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Endothelin A Receptor Antagonists; Male; Membrane Potentials; Myocardial Contraction; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channels; Rats; Receptor, Endothelin A; Sulfonamides | 2006 |
Endothelin-1 expression in blood vessels of DOCA-salt hypertensive rats treated with the combined ETA/ETB endothelin receptor antagonist bosentan.
Topics: Animals; Base Sequence; Blood Pressure; Blood Vessels; Blotting, Northern; Body Weight; Bosentan; Desoxycorticosterone; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Hypertension; Male; Molecular Sequence Data; Polymerase Chain Reaction; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA Probes; RNA-Directed DNA Polymerase; Sulfonamides | 1995 |
Chronic endothelin receptor antagonist treatment of young spontaneously hypertensive rats.
Topics: Animals; Arteries; Blood Pressure; Body Weight; Bosentan; Endothelin Receptor Antagonists; Hypertension; Myocardium; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfonamides; Time Factors | 1995 |
Effects of endothelin receptor antagonism with bosentan on peripheral nerve function in experimental diabetes.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Bosentan; Diabetes Mellitus, Experimental; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Heart Rate; Injections, Intravenous; Laser-Doppler Flowmetry; Male; Neural Conduction; Rats; Rats, Wistar; Sciatic Nerve; Streptozocin; Sulfonamides | 1995 |
Effect of chronic treatment of adult spontaneously hypertensive rats with an endothelin receptor antagonist.
Topics: Administration, Oral; Angiotensin II; Animals; Blood Pressure; Body Weight; Bosentan; Cardiomegaly; Endothelin Receptor Antagonists; Endothelins; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfonamides | 1995 |
Endothelin-1 is involved in norepinephrine-induced ventricular hypertrophy in vivo. Acute effects of bosentan, an orally active, mixed endothelin ETA and ETB receptor antagonist.
Topics: Actins; Administration, Oral; Animals; Animals, Newborn; Atrial Natriuretic Factor; Biomarkers; Body Weight; Bosentan; Cells, Cultured; Drug Evaluation, Preclinical; Endothelin Receptor Antagonists; Endothelins; Gene Expression Regulation; Hypertrophy, Left Ventricular; Male; Muscle Proteins; Myocardium; Myosin Heavy Chains; Norepinephrine; Organ Size; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; RNA, Antisense; RNA, Messenger; Sulfonamides | 1996 |
Effect of endothelin antagonism on blood pressure and vascular structure in renovascular hypertensive rats.
Topics: Animals; Blood Pressure; Blood Vessels; Body Weight; Bosentan; Endothelins; Hypertension, Renovascular; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renin; Sulfonamides | 1996 |
Endothelin antagonism in end-organ damage of spontaneously hypertensive rats. Comparison with angiotensin-converting enzyme inhibition and calcium antagonism.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Benzimidazoles; Body Weight; Bosentan; Calcium Channel Blockers; Cardiomegaly; Coronary Circulation; Enalapril; Endothelins; Fibrosis; Heart Ventricles; Hemodynamics; Hormones; Hypertension; Kidney; Mibefradil; Myocardium; Rats; Rats, Inbred SHR; Sulfonamides; Tetrahydronaphthalenes | 1996 |
Acute effect of endothelin-1 on lung oedema induced by alpha-naphthylthiourea (ANTU).
Topics: Angiotensin II; Animals; Aspartic Acid Endopeptidases; Body Weight; Bosentan; Endothelin-1; Endothelin-Converting Enzymes; Glycopeptides; Male; Metalloendopeptidases; Organ Size; Pleural Effusion; Protease Inhibitors; Pulmonary Edema; Rats; Sulfonamides; Thiourea | 1996 |
The effect of endothelin and its antagonist Bosentan on hemodynamics and microvascular exchange in cirrhotic rat liver.
Topics: Animals; Bile Acids and Salts; Bile Ducts; Bilirubin; Blood Pressure; Body Weight; Bosentan; Carbon Tetrachloride Poisoning; Cardiac Output; Endothelin-1; Hemodynamics; Hepatic Artery; Liver; Liver Circulation; Liver Cirrhosis, Biliary; Male; Metabolic Clearance Rate; Microcirculation; Organ Size; Phenobarbital; Portal System; Rats; Rats, Sprague-Dawley; Sulfonamides | 1998 |
Adrenocorticotrophic hormone-induced hypertension in the rat: effects of the endothelin antagonist bosentan.
Topics: Adrenocorticotropic Hormone; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bosentan; Disease Models, Animal; Eating; Endothelin Receptor Antagonists; Hypertension; Male; Quality Control; Rats; Rats, Sprague-Dawley; Sulfonamides; Water | 1999 |
The effects of bosentan, aminoguanidine and L-canavanine on mesenteric blood flow, spleen and liver in endotoxaemic mice.
Topics: Animals; Antihypertensive Agents; Body Weight; Bosentan; Canavanine; Dose-Response Relationship, Drug; Drug Interactions; Endothelin Receptor Antagonists; Endotoxins; Guanidines; Liver; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organ Size; Splanchnic Circulation; Spleen; Sulfonamides | 1999 |
Bosentan reduces blood pressure and the target-organ damage induced by a high-fructose diet in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bosentan; Dietary Carbohydrates; Dose-Response Relationship, Drug; Fructose; Immunohistochemistry; Kidney; Kidney Glomerulus; Male; Myocardium; Rats; Rats, Inbred WKY; Sulfonamides | 1999 |
[Cardiac and vascular hypertrophy in hypertension due to angiotensin II. Effect of losartan and bosentan].
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bosentan; Cardiomegaly; Carotid Arteries; Endothelin Receptor Antagonists; Endothelins; Follow-Up Studies; Hypertension; Hypertrophy; Losartan; Male; Organ Size; Rats; Rats, Sprague-Dawley; Sulfonamides | 2000 |
Endothelin blockade in angiotensin II hypertension: prevention and treatment studies in the rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bosentan; Carotid Arteries; Endothelin Receptor Antagonists; Hypertension; Male; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Sulfonamides | 2001 |