Page last updated: 2024-08-26

bosentan anhydrous and Bile Duct Obstruction

bosentan anhydrous has been researched along with Bile Duct Obstruction in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (28.57)	18.2507
2000's	0 (0.00)	29.6817
2010's	4 (57.14)	24.3611
2020's	1 (14.29)	2.80

Authors

Authors	Studies
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Bouwmeester, H; de Bruijn, VMP; Rietjens, IMCM	1
Beirnaert, C; Covaci, A; Cuykx, M; Laukens, K; Rodrigues, RM; Vanhaecke, T	1
Day, JS; Guan, Y; Guo, Y; Hillgren, KM; Michie, SA; Nishimura, S; Nishimura, T; Peltz, G; Takeda, ST; Wu, M; Xu, D; Yang, Z; Yates, AJ; Zheng, M	1
Vinken, M	1
Bäcker, A; Kramer, HJ; Meyer-Lehnert, H; Schwarting, K	1
Aktan, AO; Bilsel, S; Moini, H; Sarac, AM; Scapa, E	1

Reviews

1 review(s) available for bosentan anhydrous and Bile Duct Obstruction

Article	Year
Adverse Outcome Pathways and Drug-Induced Liver Injury Testing. Chemical research in toxicology, 2015, Jul-20, Volume: 28, Issue:7 Topics: Bosentan; Chemical and Drug Induced Liver Injury; Cholestasis; Fatty Liver; Humans; Liver Cirrhosis; Methotrexate; Quantitative Structure-Activity Relationship; Sulfonamides; Valproic Acid	2015

Other Studies

6 other study(ies) available for bosentan anhydrous and Bile Duct Obstruction

Article	Year
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Population pharmacokinetic model to generate mechanistic insights in bile acid homeostasis and drug-induced cholestasis. Archives of toxicology, 2022, Volume: 96, Issue:10 Topics: Bile Acids and Salts; Bosentan; Cholestasis; Homeostasis; Humans; Kinetics	2022
Untargeted liquid chromatography-mass spectrometry metabolomics to assess drug-induced cholestatic features in HepaRG® cells. Toxicology and applied pharmacology, 2019, 09-15, Volume: 379 Topics: Bosentan; Cell Line; Ceramides; Cholestasis; Chromatography, Liquid; Dose-Response Relationship, Drug; Liver; Mass Spectrometry; Metabolomics; Mitochondria, Liver; Phospholipids; Triglycerides	2019
Chimeric TK-NOG mice: a predictive model for cholestatic human liver toxicity. The Journal of pharmacology and experimental therapeutics, 2015, Volume: 352, Issue:2 Topics: Animals; Bosentan; Cefmetazole; Chemical and Drug Induced Liver Injury; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ganciclovir; Hepatocytes; Humans; Metabolic Clearance Rate; Mice, Transgenic; Species Specificity; Sulfonamides; Thymidine Kinase; Tissue Distribution; Transgenes	2015
Renal endothelin system in obstructive jaundice: its role in impaired renal function of bile-duct ligated rats. Clinical science (London, England : 1979), 1997, Volume: 92, Issue:6 Topics: Acute Kidney Injury; Animals; Bilirubin; Bosentan; Cholestasis; Creatinine; Endothelins; Female; Glomerular Filtration Rate; Kidney; Kidney Glomerulus; Rats; Rats, Sprague-Dawley; Sulfonamides	1997
Role of endothelin in obstructive jaundice. Digestive diseases and sciences, 1999, Volume: 44, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; beta-N-Acetylhexosaminidases; Bilirubin; Bosentan; Captopril; Cholestasis; Creatinine; Endothelin Receptor Antagonists; Endothelin-1; Hyaluronic Acid; Kidney Diseases; Liver; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Sulfonamides	1999