boron and Influenza-in-Birds

boron has been researched along with Influenza-in-Birds* in 2 studies

Other Studies

2 other study(ies) available for boron and Influenza-in-Birds

Article	Year
Avian Influenza Virus Detection by Optimized Peptide Termination on a Boron-Doped Diamond Electrode. ACS sensors, 2020, 02-28, Volume: 5, Issue:2 The development of a simple detection method with high sensitivity is essential for the diagnosis and surveillance of infectious diseases. Previously, we constructed a sensitive biosensor for the detection of pathological human influenza viruses using a boron-doped diamond electrode terminated with a sialyloligosaccharide receptor-mimic peptide that could bind to hemagglutinins involved in viral infection. Circulation of influenza induced by the avian virus in humans has become a major public health concern, and methods for the detection of avian viruses are urgently needed. Here, peptide density and dendrimer generation terminated on the electrode altered the efficiency of viral binding to the electrode surface, thus significantly enhancing charge-transfer resistance measured by electrochemical impedance spectroscopy. The peptide-terminated electrodes exhibited an excellent detection limit of less than one plaque-forming unit of seasonal H1N1 and H3N2 viruses. Furthermore, the improved electrode was detectable for avian viruses isolated from H5N3, H7N1, and H9N2, showing the potential for the detection of all subtypes of influenza A virus, including new subtypes. The peptide-based electrochemical architecture provided a promising approach to biosensors for ultrasensitive detection of pathogenic microorganisms. Topics: Animals; Birds; Boron; Diamond; Electrodes; Humans; Influenza in Birds; Influenza, Human; Peptides	2020
[Investigation of antiviral activity of adamantan boron derivaties on pandemic influenza virus models]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2011, Volume: 56, Issue:5-6 Comparative investigation of the virus-inhibiting activity of some boron-containing compounds showed that products BG 12 and BG 4 had the highest inhibitory effect on pandemic viruses. The minimum inhibitory concentration (MIC) of the products was 0.1 mcg/ml. The use of liposomes loaded with BG 12 molecules in the optimal concentration (0.1 mcg/ml) resulted in inhibition of the avian plague virus growth in the MDCK cells. Possible design of efficient drugs for antiviral protection based on the complexes liposomes--boron-containing compounds is discussed. Topics: Adamantane; Animals; Antiviral Agents; Birds; Boron; Cell Line; Chick Embryo; Dogs; Influenza A Virus, H7N7 Subtype; Influenza in Birds; Liposomes; Virus Replication	2011

Article

Year

Avian Influenza Virus Detection by Optimized Peptide Termination on a Boron-Doped Diamond Electrode.

ACS sensors, 2020, 02-28, Volume: 5, Issue:2

The development of a simple detection method with high sensitivity is essential for the diagnosis and surveillance of infectious diseases. Previously, we constructed a sensitive biosensor for the detection of pathological human influenza viruses using a boron-doped diamond electrode terminated with a sialyloligosaccharide receptor-mimic peptide that could bind to hemagglutinins involved in viral infection. Circulation of influenza induced by the avian virus in humans has become a major public health concern, and methods for the detection of avian viruses are urgently needed. Here, peptide density and dendrimer generation terminated on the electrode altered the efficiency of viral binding to the electrode surface, thus significantly enhancing charge-transfer resistance measured by electrochemical impedance spectroscopy. The peptide-terminated electrodes exhibited an excellent detection limit of less than one plaque-forming unit of seasonal H1N1 and H3N2 viruses. Furthermore, the improved electrode was detectable for avian viruses isolated from H5N3, H7N1, and H9N2, showing the potential for the detection of all subtypes of influenza A virus, including new subtypes. The peptide-based electrochemical architecture provided a promising approach to biosensors for ultrasensitive detection of pathogenic microorganisms.

Topics: Animals; Birds; Boron; Diamond; Electrodes; Humans; Influenza in Birds; Influenza, Human; Peptides

2020

[Investigation of antiviral activity of adamantan boron derivaties on pandemic influenza virus models].

Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2011, Volume: 56, Issue:5-6

Comparative investigation of the virus-inhibiting activity of some boron-containing compounds showed that products BG 12 and BG 4 had the highest inhibitory effect on pandemic viruses. The minimum inhibitory concentration (MIC) of the products was 0.1 mcg/ml. The use of liposomes loaded with BG 12 molecules in the optimal concentration (0.1 mcg/ml) resulted in inhibition of the avian plague virus growth in the MDCK cells. Possible design of efficient drugs for antiviral protection based on the complexes liposomes--boron-containing compounds is discussed.

Topics: Adamantane; Animals; Antiviral Agents; Birds; Boron; Cell Line; Chick Embryo; Dogs; Influenza A Virus, H7N7 Subtype; Influenza in Birds; Liposomes; Virus Replication

2011