Page last updated: 2024-08-21

boldine and Disease Models, Animal

boldine has been researched along with Disease Models, Animal in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's8 (66.67)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Atabey, N; Dayar, E; Demir, O; Durmus, N; Gidener, S; Kahraman, E; Kara, E; Yetik Anacak, G1
Li, W; Ma, W; Veeraraghavan, VP1
Balaraman, G; Kannan, P; Krishnan, P; Mari, A; Salam, S; Subramaniam, N; Sundaram, J; Thiruvengadam, D; Velli, SK1
Ezan, P; Fernández, P; Giaume, C; Koulakoff, A; Sáez, JC; Schmitt, J; Yi, C1
Guo, B; Ju, D; Liu, M; Lu, C; Qiao, S; Tan, Y; Wang, G; Xiao, C; Xu, H; Zhao, H1
Dastgheib, M; Jamshidzadeh, A; Moezi, L; Pirsalami, F; Yahosseini, S1
Jamshizadeh, A; Moezi, L; Pirsalami, F; Yahosseini, S1
Kamalidehghan, B; Looi, CY; Mustafa, MR; Paydar, M; Wong, WF; Wong, YL1
Lau, YS; Ling, WC; Murugan, D; Mustafa, MR1
Hasanpourghadi, M; Looi, CY; Mohd Esa, N; Mohebali, N; Mustafa, MR; Pandurangan, AK1
de Andrade, GM; de Lima, NM; do Carmo, MR; Fernandes, MY; Ferreira, EO; Lima, FA; Neves, KR1
Parthasarathy, S; Penumetcha, M; Santanam, N; Speisky, H1

Reviews

1 review(s) available for boldine and Disease Models, Animal

ArticleYear
Boldine Ameliorates Vascular Oxidative Stress and Endothelial Dysfunction: Therapeutic Implication for Hypertension and Diabetes.
    Journal of cardiovascular pharmacology, 2015, Volume: 65, Issue:6

    Topics: Animals; Antioxidants; Aporphines; Diabetic Angiopathies; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertension; Oxidative Stress; Signal Transduction

2015

Other Studies

11 other study(ies) available for boldine and Disease Models, Animal

ArticleYear
The role of resistin on metabolic syndrome-induced erectile dysfunction and the possible therapeutic effect of Boldine.
    Andrology, 2020, Volume: 8, Issue:6

    Topics: Animals; Antioxidants; Aporphines; Blood Glucose; Blood Pressure; Disease Models, Animal; Erectile Dysfunction; Insulin; Insulin Resistance; Male; Metabolic Syndrome; Neuromuscular Depolarizing Agents; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Receptor, Insulin; Resistin; Triglycerides; Uric Acid

2020
Effects of Boldine on Antioxidants and Allied Inflammatory Markers in Mouse Models of Asthma.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2020, Volume: 39, Issue:3

    Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Antioxidants; Aporphines; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Eosinophils; Immunoglobulin E; Lung; Male; Mice; Mice, Inbred C57BL; Ovalbumin; Reactive Oxygen Species; Respiratory Function Tests

2020
Potential Chemopreventive Role of Boldine Against Hepatocellular Carcinoma via Modulation of Cell Cycle Proteins in Rat Model.
    Anti-cancer agents in medicinal chemistry, 2021, Volume: 21, Issue:18

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Aporphines; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Liver Neoplasms; Male; Rats

2021
Inhibition of glial hemichannels by boldine treatment reduces neuronal suffering in a murine model of Alzheimer's disease.
    Glia, 2017, Volume: 65, Issue:10

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Aporphines; Cells, Cultured; Connexins; Disease Models, Animal; Gap Junctions; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Nerve Tissue Proteins; Neurites; Neuroglia; Neuromuscular Depolarizing Agents; Neurons; Neurotransmitter Agents; Presenilin-1

2017
Boldine isolated from Litsea cubeba inhibits bone resorption by suppressing the osteoclast differentiation in collagen-induced arthritis.
    International immunopharmacology, 2017, Volume: 51

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aporphines; Arthritis, Experimental; Arthritis, Rheumatoid; Bone Resorption; Cells, Cultured; Disease Models, Animal; Humans; Litsea; Male; Mice; Mice, Inbred C57BL; Osteogenesis; Osteoprotegerin; RANK Ligand; Rats; Rats, Sprague-Dawley; Receptor Activator of Nuclear Factor-kappa B; Signal Transduction

2017
Sub-chronic boldine treatment exerts anticonvulsant effects in mice.
    Neurological research, 2018, Volume: 40, Issue:2

    Topics: Animals; Anticonvulsants; Antioxidants; Aporphines; Ascorbic Acid; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Pentylenetetrazole; Seizures; Superoxide Dismutase; Time Factors

2018
Acute Boldine Treatment Induces Anti-convulsant Effects in Mice through its Antioxidant Activity.
    Drug research, 2019, Volume: 69, Issue:4

    Topics: Animals; Anticonvulsants; Antioxidants; Aporphines; Ascorbic Acid; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Pentylenetetrazole; Seizures; Superoxide Dismutase

2019
Evaluation of cytotoxic and chemotherapeutic properties of boldine in breast cancer using in vitro and in vivo models.
    Drug design, development and therapy, 2014, Volume: 8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aporphines; Breast Neoplasms; Cell Proliferation; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; L-Lactate Dehydrogenase; Molecular Structure; Rats; Structure-Activity Relationship; Tumor Cells, Cultured

2014
Boldine suppresses dextran sulfate sodium-induced mouse experimental colitis: NF-κB and IL-6/STAT3 as potential targets.
    BioFactors (Oxford, England), 2016, Volume: 42, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aporphines; Colitis; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation Mediators; Interleukin-6; Mice; NF-kappa B; RAW 264.7 Cells; Signal Transduction; STAT3 Transcription Factor; Transcription Factor RelA

2016
Neuroinflammatory response to experimental stroke is inhibited by boldine.
    Behavioural pharmacology, 2017, Volume: 28, Issue:2 and 3-Sp

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aporphines; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Injections, Intraperitoneal; Male; Memory Disorders; Mice; Neuroprotective Agents; Peumus; Stroke

2017
A novel alkaloid antioxidant, Boldine and synthetic antioxidant, reduced form of RU486, inhibit the oxidation of LDL in-vitro and atherosclerosis in vivo in LDLR(-/-) mice.
    Atherosclerosis, 2004, Volume: 173, Issue:2

    Topics: Analysis of Variance; Animals; Antioxidants; Aporphines; Arteriosclerosis; Diet, Atherogenic; Disease Models, Animal; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Male; Mice; Mice, Knockout; Mifepristone; Oxidation-Reduction; Probability; Reference Values; Sensitivity and Specificity

2004