bms-470539 and Acute-Disease

bms-470539 has been researched along with Acute-Disease* in 1 studies

Other Studies

1 other study(ies) available for bms-470539 and Acute-Disease

Article	Year
Discovery of tyrosine-based potent and selective melanocortin-1 receptor small-molecule agonists with anti-inflammatory properties. Journal of medicinal chemistry, 2003, Mar-27, Volume: 46, Issue:7 The melanocortin-1 receptor (MC-1R) is a G-protein-coupled receptor involved in inflammation and skin pigmentation. Compound 2 is the first highly potent and selective MC-1R small-molecule agonist reported. Compound 2 showed efficacy in an acute model of inflammation, which has demonstrated the role of MC-1R in modulation of inflammation. Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Humans; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Receptors, Corticotropin; Receptors, Melanocortin; Structure-Activity Relationship; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine	2003

Article

Year

Discovery of tyrosine-based potent and selective melanocortin-1 receptor small-molecule agonists with anti-inflammatory properties.

Journal of medicinal chemistry, 2003, Mar-27, Volume: 46, Issue:7

The melanocortin-1 receptor (MC-1R) is a G-protein-coupled receptor involved in inflammation and skin pigmentation. Compound 2 is the first highly potent and selective MC-1R small-molecule agonist reported. Compound 2 showed efficacy in an acute model of inflammation, which has demonstrated the role of MC-1R in modulation of inflammation.

Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Humans; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Receptors, Corticotropin; Receptors, Melanocortin; Structure-Activity Relationship; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine

2003