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bms 180448 and Myocardial Ischemia

bms 180448 has been researched along with Myocardial Ischemia in 16 studies

*Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION). [MeSH]

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	12 (75.00)	18.2507
2000's	4 (25.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ahmed, SZ; Atwal, KS; Baird, AJ; Dzwonczyk, S; Grover, GJ; Normandin, DE; Sleph, PG	1
Ahmed, SZ; Atwal, KS; Dzwonczyk, S; Ferrara, FN; Grover, GJ; Harper, TW; Kim, KS; Moreland, S; Russell, AD; Sleph, PG	1
Ahmed, SZ; Atwal, KS; Ding, CZ; Grover, GJ; Kelly, Y; Miller, AV; Misra, RN; Normandin, DE; Rovnyak, GC; Sleph, PG	1
Carroll, WA; Coghlan, MJ; Gopalakrishnan, M	1
Bogomaz, SA; Budankova, EV; Grover, GJ; Krylatov, AV; Lishmanov, AIu; Maslov, LN; Solenkova, NV	1
Burkett, DE; Grover, GJ; Parham, CS; Sadanaga, KK; Scalese, RJ	1
Atwal, KS; D'Alonzo, AJ; Grover, GJ; McCullough, JR; Sargent, CA	1
Grover, GJ	3
D'Alonzo, AJ; Darbenzio, RB; Grover, GJ; Hess, T; Sleph, PG	1
Grover, GJ; Mitroka, JG; Parham, CS; Whigan, DB	1
Grover, GJ; Sleph, PG	1
D'Alonzo, AJ; Darbenzio, RB; Grover, GJ; Hess, TA; Lodge, NJ; Normandin, DE; Sewter, JC; Sleph, PG	1
Behling, RW; Dzwonczyk, S; Grover, GJ; Malone, HJ; Sleph, PG	1
Atwal, KS; Bajgar, R; D'Alonzo, AJ; Darbenzio, RB; Garlid, KD; Grover, GJ; Hess, TA; Lodge, NJ; Paucek, P; Sleph, PG; Smith, MA	1

Reviews

4 review(s) available for bms 180448 and Myocardial Ischemia

Article	Year
Recent developments in the biology and medicinal chemistry of potassium channel modulators: update from a decade of progress. Journal of medicinal chemistry, 2001, May-24, Volume: 44, Issue:11 Topics: Adenosine Triphosphate; Angina Pectoris; Arrhythmias, Cardiac; Asthma; Calcium; Ion Channel Gating; Myocardial Ischemia; Potassium Channel Blockers; Potassium Channels; Urinary Incontinence	2001
Protective effects of ATP-sensitive potassium-channel openers in experimental myocardial ischemia. Journal of cardiovascular pharmacology, 1994, Volume: 24 Suppl 4 Topics: Action Potentials; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Dihydropyridines; Disease Models, Animal; Dogs; Guanidines; Guinea Pigs; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Picolines; Pinacidil; Potassium Channels; Pyrans; Pyrroles; Rats; Vasodilator Agents	1994
The role of ATP-sensitive potassium channels in myocardial ischemia: pharmacology and implications for the future. EXS, 1996, Volume: 76 Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Cardiotonic Agents; Disease Models, Animal; Guanidines; Humans; Ischemic Preconditioning, Myocardial; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium Channels; Pyridines	1996
Pharmacology of ATP-sensitive potassium channel (KATP) openers in models of myocardial ischemia and reperfusion. Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:4 Topics: Animals; ATP-Binding Cassette Transporters; Benzopyrans; Cromakalim; Guanidines; Humans; Ischemic Preconditioning, Myocardial; KATP Channels; Mitochondria, Heart; Models, Cardiovascular; Myocardial Ischemia; Myocardial Reperfusion; Niacinamide; Nicorandil; Picolines; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyrans; Pyrroles; Rats	1997

Other Studies

12 other study(ies) available for bms 180448 and Myocardial Ischemia

Article	Year
Cardioselective anti-ischemic ATP-sensitive potassium channel openers. 3. Structure-activity studies on benzopyranyl cyanoguanidines: modification of the cyanoguanidine portion. Journal of medicinal chemistry, 1995, Aug-18, Volume: 38, Issue:17 Topics: Adenosine Triphosphate; Animals; Guanidines; In Vitro Techniques; Magnetic Resonance Spectroscopy; Myocardial Ischemia; Potassium Channels; Rats; Structure-Activity Relationship; Vasodilator Agents	1995
Cardioselective anti-ischemic ATP-sensitive potassium channel openers. Journal of medicinal chemistry, 1993, Nov-26, Volume: 36, Issue:24 Topics: Adenosine Triphosphate; Animals; Aorta; Benzopyrans; Biological Availability; Cocaine; Cromakalim; Guanidines; Ion Channel Gating; Molecular Structure; Myocardial Ischemia; Potassium Channels; Pyrroles; Rats; Structure-Activity Relationship; Vasodilation	1993
Cardioselective antiischemic ATP-sensitive potassium channel (K(ATP)) openers. 6. Effect of modifications at C6 of benzopyranyl cyanoguanidines. Journal of medicinal chemistry, 1999, Sep-09, Volume: 42, Issue:18 Topics: Animals; Benzopyrans; Cardiotonic Agents; Glyburide; Guanidines; Heart; Muscle Contraction; Myocardial Ischemia; Potassium Channels; Rats; Vasodilation; Vasodilator Agents	1999
[Changes in cardiac resistance to arrhythmogenic effects during ATP-dependent K+ channel activation]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2003, Volume: 89, Issue:4 Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Disease Models, Animal; Guanidines; Ion Channel Gating; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Ventricular Fibrillation	2003
Protective effect of mitochondrial KATP activation in an isolated gracilis model of ischemia and reperfusion in dogs. Journal of cardiovascular pharmacology, 2003, Volume: 42, Issue:6 Topics: Animals; Benzopyrans; Cardiotonic Agents; Dogs; Female; Guanidines; Imidazoles; Male; Membrane Proteins; Myocardial Ischemia; Potassium Channels; Reperfusion	2003
Cardioprotective profile of the cardiac-selective ATP-sensitive potassium channel opener BMS-180448. Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:1 Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Aorta; Benzopyrans; Cromakalim; Decanoic Acids; Dogs; Female; Glyburide; Guanidines; Guinea Pigs; Heart; Heart Ventricles; Hydroxy Acids; In Vitro Techniques; Injections, Intravenous; Injections, Subcutaneous; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Ischemia; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley; Vasodilator Agents	1995
Glyburide-reversible cardioprotective effect of BMS-180448 is independent of action potential shortening. Cardiovascular research, 1995, Volume: 30, Issue:5 Topics: Action Potentials; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Female; Glyburide; Guanidines; Guinea Pigs; In Vitro Techniques; Ion Channel Gating; Male; Membrane Potentials; Myocardial Infarction; Myocardial Ischemia; Perfusion; Potassium Channels; Pyrroles; Vasodilator Agents	1995
BMS-180448, a novel glyburide-reversible cardioprotective agent, enhances postischemic recovery of contractile function in dogs. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:2 Topics: Animals; Benzopyrans; Cardiotonic Agents; Dogs; Glyburide; Guanidines; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Stunning; Potassium Channels; Rats; Rats, Sprague-Dawley	1996
Protective effect of K(ATP) openers in ischemic rat hearts treated with a potassium cardioplegic solution. Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:5 Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cardioplegic Solutions; Cromakalim; Guanidines; Heart; Male; Myocardial Ischemia; Potassium Channels; Pyrroles; Rats; Rats, Sprague-Dawley	1995
A comparison between the effects of BMS-180448, a novel K+ channel opener, and cromakalim in rat and dog. European journal of pharmacology, 1995, Dec-27, Volume: 294, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Benzopyrans; Blood Pressure; Cardiotonic Agents; Cromakalim; Dogs; Electrophysiology; Guanidines; Heart; Heart Conduction System; Heart Rate; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Ischemia; Potassium Channels; Pyrroles; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Species Specificity	1995
Glyburide-reversible cardioprotective effects of BMS-180448: functional and energetic considerations. Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:1 Topics: Adenosine Triphosphate; Animals; Benzopyrans; Calcium Channel Blockers; Cardiotonic Agents; Depression, Chemical; Diltiazem; Dose-Response Relationship, Drug; Glyburide; Guanidines; Heart; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Oxygen Consumption; Phosphocreatine; Potassium Channels; Rats; Rats, Sprague-Dawley	1997
Pharmacologic characterization of BMS-191095, a mitochondrial K(ATP) opener with no peripheral vasodilator or cardiac action potential shortening activity. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:3 Topics: Action Potentials; Animals; Benzopyrans; Cardiovascular Agents; Cromakalim; Decanoic Acids; Dose-Response Relationship, Drug; Glyburide; Guanidines; Guinea Pigs; Heart; Heart Conduction System; Hydroxy Acids; Imidazoles; In Vitro Techniques; Male; Mitochondria; Myocardial Ischemia; Myocardial Reperfusion; Papillary Muscles; Patch-Clamp Techniques; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Vasodilator Agents; Vasomotor System	2001