bithionol has been researched along with Ovarian Neoplasms in 4 studies
Bithionol: Halogenated anti-infective agent that is used against trematode and cestode infestations.
bithionol : An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders.
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our results suggest that BT-paclitaxel combination therapy may be effective in sensitizing ovarian cancer cells to paclitaxel treatment, thus mitigating some of the toxic effects associated with high doses of paclitaxel." | 1.46 | Evaluation of the cytotoxicity of the Bithionol-paclitaxel combination in a panel of human ovarian cancer cell lines. ( Ayyagari, VN; Brard, L; Diaz-Sylvester, PL; Hsieh, TJ, 2017) |
| "Drug resistance is a cause of ovarian cancer recurrence and low overall survival rates." | 1.40 | Bithionol inhibits ovarian cancer cell growth in vitro - studies on mechanism(s) of action. ( Ayyagari, VN; Brard, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ayyagari, VN | 4 |
| Diaz-Sylvester, PL | 2 |
| Hsieh, TJ | 2 |
| Brard, L | 4 |
| Johnston, NA | 1 |
4 other studies available for bithionol and Ovarian Neoplasms
| Article | Year |
|---|---|
Evaluation of the cytotoxicity of the Bithionol-paclitaxel combination in a panel of human ovarian cancer cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bithionol; Cell Cycle; Cell Line, Tumor; | 2017 |
Bithionol inhibits ovarian cancer cell growth in vitro - studies on mechanism(s) of action.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bithionol; Cell Cycle Checkpoints; | 2014 |
Assessment of the antitumor potential of Bithionol in vivo using a xenograft model of ovarian cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bithionol; Cell Proliferation; Female; Forkhead Transcrip | 2016 |
Evaluation of the cytotoxicity of the Bithionol - cisplatin combination in a panel of human ovarian cancer cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Bithionol; Cell Line, | 2017 |