bithionol has been researched along with Necrosis in 1 studies
Bithionol: Halogenated anti-infective agent that is used against trematode and cestode infestations.
bithionol : An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a comparison with non-irradiated cells, significant apoptosis was found in TCSA, bithionol, chlorpromazine, sparfloxacin and enoxacin at 10(-4) or 10(-5)M as well as 8-MOP as assessed by both annexin V and active caspase-3 stainings, while necrosis occurred in most of these chemicals at 10(-4)M." | 3.74 | Induction of keratinocyte apoptosis by photosensitizing chemicals plus UVA. ( Atarashi, K; Kobayashi, M; Kurita, M; Mori, K; Shimauchi, T; Tokura, Y, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kurita, M | 1 |
| Shimauchi, T | 1 |
| Kobayashi, M | 1 |
| Atarashi, K | 1 |
| Mori, K | 1 |
| Tokura, Y | 1 |
1 other study available for bithionol and Necrosis
| Article | Year |
|---|---|
Induction of keratinocyte apoptosis by photosensitizing chemicals plus UVA.
Topics: Anesthetics, Local; Anti-Infective Agents, Local; Antipsychotic Agents; Antitubercular Agents; Apopt | 2007 |