bithionol has been researched along with Fascioliasis in 31 studies
Bithionol: Halogenated anti-infective agent that is used against trematode and cestode infestations.
bithionol : An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders.
Fascioliasis: Liver disease caused by infections with parasitic flukes of the genus FASCIOLA, such as FASCIOLA HEPATICA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present work is an update evaluation of the glutathione status in patients with established fascioliasis before and after treatment with bithionol." | 7.68 | Glutathione and related enzymes in fascioliasis before and after treatment with bithionol. ( Abdel-Rahman, SZ; Abou-Bacha, LM; el-Sharkawy, AM; Salem, A, 1990) |
| "Liver biopsies from 5 patients with established fascioliasis, before and after bithionol treatment were studied by immunoalkaline phosphatase technique for relative distribution of T cells and their subpopulations." | 7.68 | Human fascioliasis: T cell subsets in liver before and after bithionol treatment. ( Abdel Rahman, ZA; Abou Basha, LM; Fadali, GA, 1990) |
| "The pathology of human fascioliasis was studied before and after bithionol treatment using light and transmission electron microscopy." | 7.68 | Human fascioliasis: ultrastructural study on the liver before and after bithionol treatment. ( Abou Basha, LM; Fadali, GA; Salem, AI, 1990) |
| "The present study is an evaluation of bithionol treatment in established fascioliasis." | 7.67 | Bithionol (Bitin) treatment in established fascioliasis in Egyptians. ( el-Hifni, SA; Farag, HF; Kandil, M; Salem, A, 1988) |
| "Bithionol was effective in all of the 13 patients and praziquantel was effective in 4 of 8 patients." | 6.40 | [Human fascioliasis: comparison of a fasciolicidal effect of bithionol and praziquantel]. ( Kodama, K, 1997) |
| "Bithionol was effective and cured the patient." | 5.28 | [Hepatic fascioliasis. Resistance to praziquantel treatment and the radiological findings]. ( Agud, JL; De Juana, P; Gea, F; Mora, P; Rábago, L; Vargas, E, 1992) |
| "Bithionol proved to be a potent fasciolicidal drug with minimal side-effects." | 5.28 | Human fascioliasis in Egypt: effect of infection and efficacy of bithionol treatment. ( Badr, NM; Bassiouny, HK; el-Daly, SM; Soliman, NK, 1991) |
| "Bithionol was given orally to hospitalized patients at the daily dose of 25 mg/kg body wt for 10 days." | 5.28 | Successful treatment of acute fascioliasis with bithionol. ( Bacq, Y; Besnier, JM; Choutet, P; Duong, TH; Metman, EH; Pavie, G, 1991) |
| "The present work is an update evaluation of the glutathione status in patients with established fascioliasis before and after treatment with bithionol." | 3.68 | Glutathione and related enzymes in fascioliasis before and after treatment with bithionol. ( Abdel-Rahman, SZ; Abou-Bacha, LM; el-Sharkawy, AM; Salem, A, 1990) |
| "Liver biopsies from 5 patients with established fascioliasis, before and after bithionol treatment were studied by immunoalkaline phosphatase technique for relative distribution of T cells and their subpopulations." | 3.68 | Human fascioliasis: T cell subsets in liver before and after bithionol treatment. ( Abdel Rahman, ZA; Abou Basha, LM; Fadali, GA, 1990) |
| "The pathology of human fascioliasis was studied before and after bithionol treatment using light and transmission electron microscopy." | 3.68 | Human fascioliasis: ultrastructural study on the liver before and after bithionol treatment. ( Abou Basha, LM; Fadali, GA; Salem, AI, 1990) |
| "The present study is an evaluation of bithionol treatment in established fascioliasis." | 3.67 | Bithionol (Bitin) treatment in established fascioliasis in Egyptians. ( el-Hifni, SA; Farag, HF; Kandil, M; Salem, A, 1988) |
| "Bithionol was effective in all of the 13 patients and praziquantel was effective in 4 of 8 patients." | 2.40 | [Human fascioliasis: comparison of a fasciolicidal effect of bithionol and praziquantel]. ( Kodama, K, 1997) |
| "Bithionol appears to be an effective treatment for fascioliasis." | 2.38 | Fascioliasis: case reports and review. ( Price, TA; Simon, GL; Tuazon, CU, 1993) |
| "Bithionol was given orally, and the patient's symptoms and biochemistry then improved, with reversal of eosinophilia." | 1.33 | Indirect evidence of ectopic pancreatic fascioliasis in a human. ( Kim, TH; Lee, OJ, 2006) |
| "Eosinophilic panniculitis is characterized by a prominent infiltration of subcutaneous fat with eosinophils." | 1.31 | Recurrent eosinophilic panniculitis associated with Fasciola hepatica infection. ( Montes, M; Ostiz, S; Perez, C; Vives, R, 2000) |
| "Bithionol was effective and cured the patient." | 1.28 | [Hepatic fascioliasis. Resistance to praziquantel treatment and the radiological findings]. ( Agud, JL; De Juana, P; Gea, F; Mora, P; Rábago, L; Vargas, E, 1992) |
| "Praziquantel was used in four patients, achieving clinical cure in three cases." | 1.28 | [Fasciola hepatica infestation. Biopathology and new diagnostic and therapeutic aspects]. ( de Górgolas, M; Fernández Guerrero, ML; Garay, J; Ponte, MC; Robledo, A; Torres, R; Verdejo, C, 1992) |
| "Bithionol proved to be a potent fasciolicidal drug with minimal side-effects." | 1.28 | Human fascioliasis in Egypt: effect of infection and efficacy of bithionol treatment. ( Badr, NM; Bassiouny, HK; el-Daly, SM; Soliman, NK, 1991) |
| "Bithionol was given orally to hospitalized patients at the daily dose of 25 mg/kg body wt for 10 days." | 1.28 | Successful treatment of acute fascioliasis with bithionol. ( Bacq, Y; Besnier, JM; Choutet, P; Duong, TH; Metman, EH; Pavie, G, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (25.81) | 18.7374 |
| 1990's | 18 (58.06) | 18.2507 |
| 2000's | 5 (16.13) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dobrucali, A | 1 |
| Yigitbasi, R | 1 |
| Erzin, Y | 1 |
| Sunamak, O | 1 |
| Polat, E | 1 |
| Yakar, H | 1 |
| Aksoy, DY | 2 |
| Kerimoglu, U | 2 |
| Oto, A | 2 |
| Erguven, S | 2 |
| Arslan, S | 2 |
| Unal, S | 2 |
| Batman, F | 2 |
| Bayraktar, Y | 2 |
| Lee, OJ | 1 |
| Kim, TH | 1 |
| Abou Basha, LM | 4 |
| Elmagdoub, AA | 1 |
| Ebeid, SA | 1 |
| Toukhy, MA | 1 |
| Michael, AI | 2 |
| Hosny, KM | 2 |
| El Zoghby, SM | 1 |
| Faraq, HF | 1 |
| El Sawy, MF | 1 |
| El-Magdoub, AA | 1 |
| El Toukhy, MA | 1 |
| Ebied, SM | 1 |
| Farag, HF | 3 |
| El Zoughby, SM | 1 |
| Faehlmann, M | 1 |
| Hambraeus, L | 1 |
| Lindqvist, L | 1 |
| Paulsen, O | 1 |
| Pehrson, PO | 1 |
| Jiménez, C | 1 |
| Jiménez, FJ | 1 |
| Hoyos, ML | 1 |
| Monllau, A | 1 |
| Osman, MM | 1 |
| Rashwan, E | 1 |
| Espino, AM | 1 |
| Finlay, CM | 1 |
| Price, TA | 1 |
| Tuazon, CU | 1 |
| Simon, GL | 1 |
| Abreu, F | 1 |
| Aidos, A | 1 |
| Rebelo, I | 1 |
| Lacerda, C | 1 |
| Palminha, JM | 1 |
| el-Sayad, MH | 1 |
| el-Bahy, MM | 1 |
| el Sayad, MH | 1 |
| Kodama, K | 1 |
| Suou, T | 1 |
| Mitsuda, A | 1 |
| Fukui, A | 1 |
| Perez, C | 1 |
| Vives, R | 1 |
| Montes, M | 1 |
| Ostiz, S | 1 |
| Pawlov, P | 1 |
| Georgiev, B | 1 |
| Mereminskiĭ, AI | 1 |
| Gluzman, IIa | 1 |
| Mora, P | 1 |
| Gea, F | 1 |
| Agud, JL | 1 |
| Rábago, L | 1 |
| Vargas, E | 1 |
| De Juana, P | 1 |
| de Górgolas, M | 1 |
| Torres, R | 1 |
| Verdejo, C | 1 |
| Garay, J | 1 |
| Robledo, A | 1 |
| Ponte, MC | 1 |
| Fernández Guerrero, ML | 1 |
| Bassiouny, HK | 1 |
| Soliman, NK | 1 |
| el-Daly, SM | 1 |
| Badr, NM | 1 |
| Bacq, Y | 1 |
| Besnier, JM | 1 |
| Duong, TH | 1 |
| Pavie, G | 1 |
| Metman, EH | 1 |
| Choutet, P | 1 |
| Abdel-Rahman, SZ | 1 |
| el-Sharkawy, AM | 1 |
| Abou-Bacha, LM | 1 |
| Salem, A | 2 |
| Farid, Z | 3 |
| Mansour, N | 1 |
| Kamal, M | 2 |
| Kamal, K | 1 |
| Safwat, Y | 1 |
| Woody, JN | 1 |
| Abdel Rahman, ZA | 1 |
| Fadali, GA | 2 |
| Salem, AI | 1 |
| Trabolsi, B | 1 |
| Boctor, F | 1 |
| Hafez, A | 1 |
| Woody, J | 1 |
| el-Hifni, SA | 1 |
| Kandil, M | 1 |
4 reviews available for bithionol and Fascioliasis
| Article | Year |
|---|---|
[Hepatic fascioliasis: the usefulness of CT and US].
Topics: Adult; Bithionol; Fascioliasis; Humans; Liver; Male; Time Factors; Tomography, X-Ray Computed; Ultra | 1995 |
Fascioliasis: case reports and review.
Topics: Bithionol; Fascioliasis; Female; Humans; Male; Middle Aged; Praziquantel | 1993 |
[Human fascioliasis: comparison of a fasciolicidal effect of bithionol and praziquantel].
Topics: Aged; Aged, 80 and over; Antiplatyhelmintic Agents; Bithionol; Drug Administration Schedule; Fasciol | 1997 |
[Fascioliasis].
Topics: Animals; Antiplatyhelmintic Agents; Bithionol; Diagnosis, Differential; Fasciola hepatica; Fasciolia | 1999 |
27 other studies available for bithionol and Fascioliasis
| Article | Year |
|---|---|
Fasciola hepatica infestation as a very rare cause of extrahepatic cholestasis.
Topics: Adult; Animals; Antiplatyhelmintic Agents; Bithionol; Cholangiopancreatography, Endoscopic Retrograd | 2004 |
Infection with Fasciola hepatica.
Topics: Animals; Antiplatyhelmintic Agents; Benzimidazoles; Biopsy; Bithionol; Cholangiography; Enzyme-Linke | 2005 |
Fasciola hepatica infection: clinical and computerized tomographic findings of ten patients.
Topics: Abdominal Pain; Adolescent; Adult; Antiplatyhelmintic Agents; Bithionol; Fascioliasis; Female; Human | 2006 |
Indirect evidence of ectopic pancreatic fascioliasis in a human.
Topics: Animals; Antibodies, Helminth; Antiplatyhelmintic Agents; Bithionol; Diagnosis, Differential; Fascio | 2006 |
Effect of bithionol on B-glucuronidase in serum and liver of rabbits infected with Fasciola gigantica.
Topics: Animals; Bithionol; Fascioliasis; Glucuronidase; Liver; Male; Phenols; Rabbits | 1983 |
Alpha esterase enzyme in liver of rabbits infected with Fasciola gigantica and treated with bithionol.
Topics: Animals; Bithionol; Esterases; Fascioliasis; Liver; Liver Diseases, Parasitic; Male; Rabbits | 1982 |
[The liver fluke - the 1st imported cases?].
Topics: Adult; Bithionol; Fascioliasis; Feces; Female; Humans; Liver; Phenols; Sweden | 1981 |
Phagocytic activity of neutrophils in human fasciolosis before and after treatment.
Topics: Animals; Bithionol; Fasciola; Fascioliasis; Feces; Female; Follow-Up Studies; Humans; Luminescent Me | 1995 |
Sandwich enzyme-linked immunosorbent assay for detection of excretory secretory antigens in humans with fascioliasis.
Topics: Animals; Antibodies, Helminth; Antibodies, Monoclonal; Antigens, Helminth; Bithionol; Enzyme-Linked | 1994 |
[Value of bithionol in the treatment of hepatic fascioliasis in children].
Topics: Antiplatyhelmintic Agents; Bithionol; Child; Fascioliasis; Female; Humans | 1996 |
Compartive studies on the effect of bithionol, praziqantel and triclabendazole in rabbit's fascioliasis. 1. Parasitological studies.
Topics: Animals; Antiplatyhelmintic Agents; Benzimidazoles; Bithionol; Fasciola; Fascioliasis; Female; Liver | 1997 |
Comparative studies on the effect of bithionol, praziquantel and triclabendazole in rabbit's fascioliasis.
Topics: Animals; Anthelmintics; Benzimidazoles; Bithionol; Disease Models, Animal; Fasciola; Fascioliasis; P | 1997 |
Comparative studies on the effect of Bithionol, Praziquantel and Triclabendazole in rabbit's fascioliasis.
Topics: Animals; Anthelmintics; Benzimidazoles; Bithionol; Egypt; Fasciola; Fascioliasis; Humans; Praziquant | 1997 |
Recurrent eosinophilic panniculitis associated with Fasciola hepatica infection.
Topics: Animals; Antiplatyhelmintic Agents; Bithionol; Eosinophilia; Fasciola hepatica; Fascioliasis; Female | 2000 |
[Efficacy of Coriban and Disto-5-Cogla in fascioliasis and paramphistomians of domestic ruminants].
Topics: Acetanilides; Animals; Bithionol; Diamfenetide; Fascioliasis; Phenols; Sheep; Sheep Diseases; Tremat | 1976 |
[Bitifen in fascioliasis and paramphistomiasis].
Topics: Animals; Anthelmintics; Bithionol; Cattle; Cattle Diseases; Drug Combinations; Drug Evaluation; Fasc | 1975 |
[Hepatic fascioliasis. Resistance to praziquantel treatment and the radiological findings].
Topics: Aged; Bithionol; Drug Resistance; Fascioliasis; Humans; Liver; Liver Diseases, Parasitic; Male; Praz | 1992 |
[Fasciola hepatica infestation. Biopathology and new diagnostic and therapeutic aspects].
Topics: Adult; Aged; Animals; Bithionol; Fasciola hepatica; Fascioliasis; Female; Food Contamination; Hemagg | 1992 |
Human fascioliasis in Egypt: effect of infection and efficacy of bithionol treatment.
Topics: Adolescent; Adult; Anemia, Hypochromic; Bithionol; Egypt; Eosinophilia; Erythrocyte Indices; Fasciol | 1991 |
Successful treatment of acute fascioliasis with bithionol.
Topics: Acute Disease; Adult; Aged; Bithionol; Eosinophilia; Fascioliasis; Female; Hemagglutination Tests; H | 1991 |
Glutathione and related enzymes in fascioliasis before and after treatment with bithionol.
Topics: Animals; Bithionol; Child; Erythrocytes; Fasciola; Fascioliasis; Feces; gamma-Glutamyltransferase; G | 1990 |
The treatment of acute Fasciola hepatica infection in children.
Topics: Acute Disease; Animals; Bithionol; Child; Child, Preschool; Emetine; Fasciola hepatica; Fascioliasis | 1990 |
Human fascioliasis: T cell subsets in liver before and after bithionol treatment.
Topics: Bithionol; Fascioliasis; Humans; Immunoenzyme Techniques; Immunohistochemistry; Liver; T-Lymphocytes | 1990 |
Human fascioliasis: ultrastructural study on the liver before and after bithionol treatment.
Topics: Biopsy, Needle; Bithionol; Fascioliasis; Humans; Liver; Microscopy, Electron | 1990 |
Unsuccessful use of praziquantel to treat acute fascioliasis in children.
Topics: Acute Disease; Bithionol; Child; Child, Preschool; Emetine; Fascioliasis; Female; Humans; Male; Praz | 1986 |
Treatment of acute toxaemic fascioliasis.
Topics: Acute Disease; Bithionol; Child; Child, Preschool; Emetine; Fascioliasis; Female; Humans; Male; Phen | 1988 |
Bithionol (Bitin) treatment in established fascioliasis in Egyptians.
Topics: Adolescent; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Bith | 1988 |