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bithionol and Dermatitis, Contact, Phototoxic

bithionol has been researched along with Dermatitis, Contact, Phototoxic in 5 studies

Bithionol: Halogenated anti-infective agent that is used against trematode and cestode infestations.
bithionol : An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone was shown to have no effect on cellular glutathione levels, which suggests that an alternative mechanism of detoxification was occurring in this case."1.34An evaluation of the effects of photoactivation of bithionol, amiodarone and chlorpromazine on human keratinocytes in vitro. ( Clothier, RH; Khammo, N; Reid, L, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Hinoshita, M3
Abe, T3
Sato, A3
Maeda, Y3
Takeyoshi, M3
Toyooka, T1
Ishihama, M1
Ibuki, Y1
JILLSON, OF1
BAUGHMAN, RD2
Reid, L1
Khammo, N1
Clothier, RH1

Other Studies

5 other studies available for bithionol and Dermatitis, Contact, Phototoxic

ArticleYear
False-negative chemicals in ESR-based photosafety test (ESR-PT) and their significance for photosafety evaluations: examples of bithionol, fenticlor and cilnidipine.
    The Journal of toxicological sciences, 2022, Volume: 47, Issue:12

    Topics: Bithionol; Chlorophenols; Computer Simulation; Dermatitis, Photoallergic; Dermatitis, Phototoxic; Hu

2022
False-negative chemicals in ESR-based photosafety test (ESR-PT) and their significance for photosafety evaluations: examples of bithionol, fenticlor and cilnidipine.
    The Journal of toxicological sciences, 2022, Volume: 47, Issue:12

    Topics: Bithionol; Chlorophenols; Computer Simulation; Dermatitis, Photoallergic; Dermatitis, Phototoxic; Hu

2022
False-negative chemicals in ESR-based photosafety test (ESR-PT) and their significance for photosafety evaluations: examples of bithionol, fenticlor and cilnidipine.
    The Journal of toxicological sciences, 2022, Volume: 47, Issue:12

    Topics: Bithionol; Chlorophenols; Computer Simulation; Dermatitis, Photoallergic; Dermatitis, Phototoxic; Hu

2022
False-negative chemicals in ESR-based photosafety test (ESR-PT) and their significance for photosafety evaluations: examples of bithionol, fenticlor and cilnidipine.
    The Journal of toxicological sciences, 2022, Volume: 47, Issue:12

    Topics: Bithionol; Chlorophenols; Computer Simulation; Dermatitis, Photoallergic; Dermatitis, Phototoxic; Hu

2022
Phosphorylation of histone H2AX is a powerful tool for detecting chemical photogenotoxicity.
    The Journal of investigative dermatology, 2011, Volume: 131, Issue:6

    Topics: Bithionol; Cell Survival; Cells, Cultured; Coumarins; Dermatitis, Phototoxic; DNA Breaks, Double-Str

2011
CONTACT PHOTODERMATITIS FROM BITHIONOL.
    Archives of dermatology, 1963, Volume: 88

    Topics: Anti-Infective Agents, Local; Bithionol; Dermatitis; Dermatitis, Contact; Dermatitis, Phototoxic; Ge

1963
CONTACT PHOTODERMATITIS FROM BITHIONOL. II. CROSS-SENSITIVITIES TO HEXACHLOROPHENE AND SALICYLANILIDES.
    Archives of dermatology, 1964, Volume: 90

    Topics: Anilides; Anti-Infective Agents; Anti-Infective Agents, Local; Bithionol; Dermatitis, Phototoxic; Dr

1964
An evaluation of the effects of photoactivation of bithionol, amiodarone and chlorpromazine on human keratinocytes in vitro.
    Alternatives to laboratory animals : ATLA, 2007, Volume: 35, Issue:5

    Topics: Amiodarone; Animal Testing Alternatives; Anti-Arrhythmia Agents; Anti-Infective Agents, Local; Antio

2007