bithionol has been researched along with Cancer of Ovary in 4 studies
Bithionol: Halogenated anti-infective agent that is used against trematode and cestode infestations.
bithionol : An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our results suggest that BT-paclitaxel combination therapy may be effective in sensitizing ovarian cancer cells to paclitaxel treatment, thus mitigating some of the toxic effects associated with high doses of paclitaxel." | 1.46 | Evaluation of the cytotoxicity of the Bithionol-paclitaxel combination in a panel of human ovarian cancer cell lines. ( Ayyagari, VN; Brard, L; Diaz-Sylvester, PL; Hsieh, TJ, 2017) |
| "Drug resistance is a cause of ovarian cancer recurrence and low overall survival rates." | 1.40 | Bithionol inhibits ovarian cancer cell growth in vitro - studies on mechanism(s) of action. ( Ayyagari, VN; Brard, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ayyagari, VN | 4 |
| Diaz-Sylvester, PL | 2 |
| Hsieh, TJ | 2 |
| Brard, L | 4 |
| Johnston, NA | 1 |
4 other studies available for bithionol and Cancer of Ovary
| Article | Year |
|---|---|
Evaluation of the cytotoxicity of the Bithionol-paclitaxel combination in a panel of human ovarian cancer cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bithionol; Cell Cycle; Cell Line, Tumor; | 2017 |
Bithionol inhibits ovarian cancer cell growth in vitro - studies on mechanism(s) of action.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bithionol; Cell Cycle Checkpoints; | 2014 |
Assessment of the antitumor potential of Bithionol in vivo using a xenograft model of ovarian cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bithionol; Cell Proliferation; Female; Forkhead Transcrip | 2016 |
Evaluation of the cytotoxicity of the Bithionol - cisplatin combination in a panel of human ovarian cancer cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Bithionol; Cell Line, | 2017 |