bisoprolol has been researched along with Uremia in 2 studies
Bisoprolol: A cardioselective beta-1 adrenergic blocker. It is effective in the management of HYPERTENSION and ANGINA PECTORIS.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of bisoprolol on transient myocardial ischemia have been compared with those of nifedipine in patients with coronary artery disease in end-stage renal failure maintained on haemodialysis." | 5.08 | [Effectiveness and tolerability of bisoprolol vs. nifedipine in uremic patients with ischemic cardiopathy in dialysis treatment]. ( Cice, G; Di Benedetto, A; Ferrara, L; Iacono, A; Sorice, P; Tagliamonte, E, 1997) |
| " In healthy subjects peak and trough steady-state concentrations of 52 micrograms/L and 11 micrograms/L, respectively, an elimination half-life of 10." | 1.27 | Pharmacokinetics of bisoprolol during repeated oral administration to healthy volunteers and patients with kidney or liver disease. ( Demers, HG; Kirch, W; Leopold, G; Ohnhaus, EE; Pabst, J; Rose, I, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cice, G | 1 |
| Di Benedetto, A | 1 |
| Tagliamonte, E | 1 |
| Ferrara, L | 1 |
| Sorice, P | 1 |
| Iacono, A | 1 |
| Kirch, W | 1 |
| Rose, I | 1 |
| Demers, HG | 1 |
| Leopold, G | 1 |
| Pabst, J | 1 |
| Ohnhaus, EE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Bisoprolol Plasma Residual Concentrations for the Optimization of Drug Management in Heart Failure With Mild to Reduced Ejection Fraction[NCT03644446] | 81 participants (Anticipated) | Observational [Patient Registry] | 2017-11-02 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for bisoprolol and Uremia
| Article | Year |
|---|---|
[Effectiveness and tolerability of bisoprolol vs. nifedipine in uremic patients with ischemic cardiopathy in dialysis treatment].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Calcium Channel Blockers; Female; Humans; Male; Middle Aged | 1997 |
1 other study available for bisoprolol and Uremia
| Article | Year |
|---|---|
Pharmacokinetics of bisoprolol during repeated oral administration to healthy volunteers and patients with kidney or liver disease.
Topics: Adrenergic beta-Antagonists; Adult; Bisoprolol; Blood Proteins; Half-Life; Hepatitis; Humans; Kidney | 1987 |