Page last updated: 2024-10-23

bisoprolol and Long QT Syndrome

bisoprolol has been researched along with Long QT Syndrome in 7 studies

Bisoprolol: A cardioselective beta-1 adrenergic blocker. It is effective in the management of HYPERTENSION and ANGINA PECTORIS.

Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.

Research Excerpts

ExcerptRelevanceReference
" We describe two cases where a switch to bisoprolol resulted in worsening of arrhythmia control: A man with LQT2, asymptomatic on propranolol, experienced syncope after switching to bisoprolol 5 mg daily."7.83Two Cases of LQT Syndrome with Malignant Syncope after Switch from Propranolol to Bisoprolol. ( Jensen, SM; Kesek, M; Rydberg, A, 2016)
" We describe two cases where a switch to bisoprolol resulted in worsening of arrhythmia control: A man with LQT2, asymptomatic on propranolol, experienced syncope after switching to bisoprolol 5 mg daily."3.83Two Cases of LQT Syndrome with Malignant Syncope after Switch from Propranolol to Bisoprolol. ( Jensen, SM; Kesek, M; Rydberg, A, 2016)
"Bisoprolol treatment results in QTc shortening in gene-positive LQT1 and LQT2 patients and is well tolerated during long-term administration."1.43Experience with bisoprolol in long-QT1 and long-QT2 syndrome. ( Adler, A; Al-Sabeq, B; Andrade, JG; Bennett, MT; Chakrabarti, S; Deyell, MW; Green, M; Kerr, CR; Klein, GJ; Krahn, AD; Laksman, ZW; Padfield, GJ; Steinberg, C; Yee, R; Yeung-Lai-Wah, JA, 2016)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Higa, A1
Hoshi, H1
Yanagisawa, Y1
Ito, E1
Morisawa, G1
Imai, JI1
Watanabe, S1
Takagi, M1
Fazio, G1
Vernuccio, F1
Lo Re, G1
Grutta, G1
Mongiovì, M1
Kesek, M1
Rydberg, A1
Jensen, SM1
Steinberg, C1
Padfield, GJ1
Al-Sabeq, B1
Adler, A1
Yeung-Lai-Wah, JA1
Kerr, CR1
Deyell, MW1
Andrade, JG1
Bennett, MT1
Yee, R1
Klein, GJ1
Green, M1
Laksman, ZW1
Krahn, AD1
Chakrabarti, S1
Kuusela, J1
Kim, J1
Räsänen, E1
Aalto-Setälä, K1
Yoshiga, Y1
Shimizu, A1
Yamagata, T1
Hayano, T1
Ueyama, T1
Ohmura, M1
Itagaki, K1
Kimura, M1
Matsuzaki, M1
Dubrey, SW1
Grocott-Mason, R1

Trials

1 trial available for bisoprolol and Long QT Syndrome

ArticleYear
Beta-blocker decreases the increase in QT dispersion and transmural dispersion of repolarization induced by bepridil.
    Circulation journal : official journal of the Japanese Circulation Society, 2002, Volume: 66, Issue:11

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Bepridil; Bisoprolol

2002

Other Studies

6 other studies available for bisoprolol and Long QT Syndrome

ArticleYear
Evaluation system for arrhythmogenic potential of drugs using human-induced pluripotent stem cell-derived cardiomyocytes and gene expression analysis.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:6

    Topics: Amlodipine; Arrhythmias, Cardiac; Benzimidazoles; Biphenyl Compounds; Bisoprolol; Cardiotoxicity; Ce

2017
Role of bisoprolol in patients with long QT syndrome.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2013, Volume: 18, Issue:5

    Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Adult; Bisoprolol; Child; Electrocardiography; E

2013
Two Cases of LQT Syndrome with Malignant Syncope after Switch from Propranolol to Bisoprolol.
    Pacing and clinical electrophysiology : PACE, 2016, Volume: 39, Issue:3

    Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Bisoprolol; Drug Administration Schedule; Humans; L

2016
Experience with bisoprolol in long-QT1 and long-QT2 syndrome.
    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2016, Volume: 47, Issue:2

    Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Bisoprolol; Canada; Cardiotonic Agents; Cohort Studie

2016
The Effects of Pharmacological Compounds on Beat Rate Variations in Human Long QT-Syndrome Cardiomyocytes.
    Stem cell reviews and reports, 2016, Volume: 12, Issue:6

    Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Bisoprolol; Cells, Cultured; Dose-Response Relationsh

2016
Drug-induced QT prolongation: consequences and current dilemma.
    British journal of hospital medicine (London, England : 2005), 2007, Volume: 68, Issue:1

    Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Bisoprolol; Electrocardiography; Female; Humans; Long QT

2007