bisoprolol has been researched along with Liver Dysfunction in 3 studies
Bisoprolol: A cardioselective beta-1 adrenergic blocker. It is effective in the management of HYPERTENSION and ANGINA PECTORIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In healthy subjects peak and trough steady-state concentrations of 52 micrograms/L and 11 micrograms/L, respectively, an elimination half-life of 10." | 1.27 | Pharmacokinetics of bisoprolol during repeated oral administration to healthy volunteers and patients with kidney or liver disease. ( Demers, HG; Kirch, W; Leopold, G; Ohnhaus, EE; Pabst, J; Rose, I, 1987) |
| "The pharmacokinetic profile of an oral single dose of the new cardioselective beta-blocking agent, bisoprolol, was studied in patients with moderate and severe liver disease (Pugh group B and C, respectively) and normal subjects." | 1.27 | Single oral dose pharmacokinetics of bisoprolol 10 mg in liver disease. ( Dagap, K; Hayes, PC; Ioannides, C; Jenkins, D; Johnston, A; Thomas, P; Vavianos, P; Williams, R, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wernet, A | 1 |
| Sibert, A | 1 |
| Paugam-Burtz, C | 1 |
| Geffroy, A | 1 |
| Pease, S | 1 |
| Belghiti, J | 1 |
| Vilgrain, V | 1 |
| Mantz, J | 1 |
| Kirch, W | 1 |
| Rose, I | 1 |
| Demers, HG | 1 |
| Leopold, G | 1 |
| Pabst, J | 1 |
| Ohnhaus, EE | 1 |
| Hayes, PC | 1 |
| Jenkins, D | 1 |
| Vavianos, P | 1 |
| Dagap, K | 1 |
| Johnston, A | 1 |
| Ioannides, C | 1 |
| Thomas, P | 1 |
| Williams, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Bisoprolol Plasma Residual Concentrations for the Optimization of Drug Management in Heart Failure With Mild to Reduced Ejection Fraction[NCT03644446] | 81 participants (Anticipated) | Observational [Patient Registry] | 2017-11-02 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for bisoprolol and Liver Dysfunction
| Article | Year |
|---|---|
Ethanol-induced coma after therapeutic ethanol injection of a hepatic cyst.
Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Coma; Cysts; Ethanol; Female; Humans; Hypertension; L | 2008 |
Pharmacokinetics of bisoprolol during repeated oral administration to healthy volunteers and patients with kidney or liver disease.
Topics: Adrenergic beta-Antagonists; Adult; Bisoprolol; Blood Proteins; Half-Life; Hepatitis; Humans; Kidney | 1987 |
Single oral dose pharmacokinetics of bisoprolol 10 mg in liver disease.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Bisoprolol; Blood Urea Nitrogen; Creatinin | 1987 |