bisoprolol has been researched along with Essential Hypertension in 7 studies
Bisoprolol: A cardioselective beta-1 adrenergic blocker. It is effective in the management of HYPERTENSION and ANGINA PECTORIS.
Essential Hypertension: Hypertension that occurs without known cause, or preexisting renal disease. Associated polymorphisms for a number of genes have been identified, including AGT, GNB3, and ECE1. OMIM: 145500
| Excerpt | Relevance | Reference |
|---|---|---|
| "TY-0201 (TY) is a new drug absorbed by the transdermal delivery system developed for the treatment of hypertension, which contains the free base of bisoprolol fumarate that is widely used." | 9.17 | Comparison of efficacy and safety between bisoprolol transdermal patch (TY-0201) and bisoprolol fumarate oral formulation in Japanese patients with grade I or II essential hypertension: randomized, double-blind, placebo-controlled study. ( Kuwajima, I; Matsuoka, H; Mitamura, H; Saruta, T; Shimada, K, 2013) |
| " The Genetics of Drug Responsiveness in Essential Hypertension (GENRES) study is a double-blind, placebo-controlled cross-over study where each subject received amlodipine, bisoprolol,hydrochlorothiazide, and losartan, each as a monotherapy, in a randomized order." | 5.20 | Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs. ( Boerwinkle, E; Chapman, AB; Cooper-DeHoff, RM; Donner, KM; Frau, F; Glorioso, N; Glorioso, V; Gong, Y; Gums, JG; Hiltunen, TP; Johnson, JA; Kontula, KK; Ripatti, S; Saarela, J; Salvi, E; Sarin, AP; Turner, ST; Zaninello, R, 2015) |
| "TY-0201 (TY) is a new drug absorbed by the transdermal delivery system developed for the treatment of hypertension, which contains the free base of bisoprolol fumarate that is widely used." | 5.17 | Comparison of efficacy and safety between bisoprolol transdermal patch (TY-0201) and bisoprolol fumarate oral formulation in Japanese patients with grade I or II essential hypertension: randomized, double-blind, placebo-controlled study. ( Kuwajima, I; Matsuoka, H; Mitamura, H; Saruta, T; Shimada, K, 2013) |
| "Treatment with amlodipine, candesartan, or indapamide did not significantly affect plasma visfatin levels." | 1.43 | Effects of antihypertensive treatment on plasma apelin, resistin, and visfatin concentrations. ( Piecha, G; Skoczylas, A; Więcek, A, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ostroumova, OD | 1 |
| Kochetkov, AI | 1 |
| Guseva, TF | 1 |
| Zykova, AA | 1 |
| Zhou, WJ | 1 |
| Wang, RY | 1 |
| Li, Y | 1 |
| Chen, DR | 1 |
| Chen, EZ | 1 |
| Zhu, DL | 1 |
| Gao, PJ | 1 |
| Matsuoka, H | 1 |
| Kuwajima, I | 1 |
| Shimada, K | 1 |
| Mitamura, H | 1 |
| Saruta, T | 1 |
| Hiltunen, TP | 1 |
| Donner, KM | 1 |
| Sarin, AP | 1 |
| Saarela, J | 1 |
| Ripatti, S | 1 |
| Chapman, AB | 1 |
| Gums, JG | 1 |
| Gong, Y | 1 |
| Cooper-DeHoff, RM | 1 |
| Frau, F | 1 |
| Glorioso, V | 1 |
| Zaninello, R | 1 |
| Salvi, E | 1 |
| Glorioso, N | 1 |
| Boerwinkle, E | 1 |
| Turner, ST | 1 |
| Johnson, JA | 1 |
| Kontula, KK | 1 |
| Czarnecka, D | 1 |
| Koch, EM | 1 |
| Gottwald-Hostalek, U | 1 |
| Skoczylas, A | 1 |
| Piecha, G | 1 |
| Więcek, A | 1 |
| Suojanen, L | 1 |
| Haring, A | 1 |
| Tikkakoski, A | 1 |
| Koskela, JK | 1 |
| Tahvanainen, AM | 1 |
| Huhtala, H | 1 |
| Kähönen, M | 1 |
| Sipilä, K | 1 |
| Eräranta, A | 1 |
| Mustonen, JT | 1 |
| Kivistö, K | 1 |
| Pörsti, IH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Study: Effects of Bisoprolol and Atenolol on Sympathetic Nervous Activity and Central Aortic Pressure in Patients With Essential Hypertension[NCT01762436] | Phase 4 | 109 participants (Actual) | Interventional | 2010-11-30 | Completed | ||
| A Randomised Double-blind Cross-over Single-centre Study on Molecular Genetics of Drug Responsiveness in Essential Hypertension[NCT03276598] | Phase 4 | 233 participants (Actual) | Interventional | 1999-11-25 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for bisoprolol and Essential Hypertension
| Article | Year |
|---|---|
A randomized controlled study on the effects of bisoprolol and atenolol on sympathetic nervous activity and central aortic pressure in patients with essential hypertension.
Topics: Adult; Antihypertensive Agents; Arterial Pressure; Atenolol; Baroreflex; Bisoprolol; Essential Hyper | 2013 |
Comparison of efficacy and safety between bisoprolol transdermal patch (TY-0201) and bisoprolol fumarate oral formulation in Japanese patients with grade I or II essential hypertension: randomized, double-blind, placebo-controlled study.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Asian People; Bisoprolol; Blood Pressure; Dose | 2013 |
Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs.
Topics: Adult; Aldehyde Oxidoreductases; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compo | 2015 |
Haemodynamic Influences of Bisoprolol in Hypertensive Middle-Aged Men: A Double-Blind, Randomized, Placebo-Controlled Cross-Over Study.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Antihypertensive Agents; Bisoprolol; Blood Pressure; | 2017 |
3 other studies available for bisoprolol and Essential Hypertension
| Article | Year |
|---|---|
[Sympathetic Nervous System Activation in Pathogenesis of Development of Essential Hypertension and Its Role in Target-Organs Damage in Young and Middle Aged Adults: the Cardioprotective Capabilities of Bisoprolol].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Essential Hypertension; Humans; Middle Aged; Sympathetic Ne | 2018 |
Benefits of a fixed-dose combination of bisoprolol and amlodipine in the treatment of hypertension in daily practice: results of more than 4000 patients.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Pressure; Dru | 2015 |
Effects of antihypertensive treatment on plasma apelin, resistin, and visfatin concentrations.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; | 2016 |