Compounds > bisoprolol
Page last updated: 2024-10-23

bisoprolol and Arteriosclerosis, Coronary

bisoprolol has been researched along with Arteriosclerosis, Coronary in 15 studies

Bisoprolol: A cardioselective beta-1 adrenergic blocker. It is effective in the management of HYPERTENSION and ANGINA PECTORIS.

Research Excerpts

ExcerptRelevanceReference
"Bisoprolol is a selective beta adrenergic antagonist commonly used in treatment of coronary artery disease (CAD)."9.27Population Pharmacokinetic Analysis of Bisoprolol in Patients with Stable Coronary Artery Disease. ( Deljanin-Ilic, M; Jankovic, SM; Jevtovic-Stoimenov, T; Milovanovic, JR; Nikolic, ML; Nikolic, VN; Stojanovic, SS; Stokanovic, D; Zivanovic, S, 2018)
" This study assessed the effectiveness and tolerability of bisoprolol/perindopril (Bis/Per) single-pill combination (SPC) in Russian patients with hypertension and coronary artery disease (CAD) treated in routine clinical practice."8.02Effectiveness and Tolerability of the Single-Pill Combination of Bisoprolol and Perindopril in Patients with Arterial Hypertension and Stable Coronary Artery Disease in Daily Clinical Practice: The STYLE Study. ( Boytsov, SA; Burtsev, YP; Karpov, YA; Khomitskaya, YV, 2021)
"Bisoprolol can effectively reduce RHR in Asian CAD patients with comorbid hypertension and hence, improve CCCO without affecting their blood pressure."7.96Resting heart rate control and prognosis in coronary artery disease patients with hypertension previously treated with bisoprolol: a sub-group analysis of the BISO-CAD study. ( Chen, XP; Chen, YD; Fu, GS; Huang, SA; Kim, DS; Kim, TH; Liu, SW; Ma, TR; Pham, VN; Truong, BQ; Yang, XC; Yang, Y, 2020)
"to compare the antianginal and pulse slowing effects, the impact on the ectopic myocardial activity as well as the safety of the treatment with beta - adrenoblocker bisoprolol, calcium antagonist verapamil and the combination of bisoprolol with amlodipine in patients with stable angina (SA) and bronchial asthma (BA)."7.91[Possibilities of cardioselective beta - blocker bisoprolol therapy in patients having coronary artery disease and bronchial asthma]. ( Grigorieva, NY; Ilyushina, TP; Yashina, EM, 2019)
"To evaluate the association between decrease in resting heart rate (RHR) and occurrence of composite cardiac clinical outcomes in coronary artery disease (CAD) patients after bisoprolol treatment."7.88Heart rate control is associated with reduced cardiovascular events in Asian patients with coronary artery disease treated with bisoprolol (BISO-CAD): results from a multi-national, real-world experience. ( Chen, X; Chen, Y; Fu, G; Huang, S; Kim, DS; Kim, TH; Liu, S; Ma, T; Nguyen Pham, V; Quang Truong, B; Yang, X; Yang, Y, 2018)
"We compared the efficacy of perioperative ivabradine, bisoprolol, or both for prevention of postoperative atrial fibrillation (AF) in patients undergoing coronary artery bypass grafting (CABG)."7.83Atrial Fibrillation After Coronary Artery Bypass Surgery: Can Ivabradine Reduce Its Occurrence? ( Abdel-Salam, Z; Nammas, W, 2016)
"Bisoprolol was started at 1."6.76Comparison of effectiveness of carvedilol versus bisoprolol for prevention of postdischarge atrial fibrillation after coronary artery bypass grafting in patients with heart failure. ( Arisi, G; Caminiti, G; Iellamo, F; Madonna, M; Marazzi, G; Massaro, R; Righi, D; Rosano, GM; Volterrani, M, 2011)
"Bisoprolol is a selective beta adrenergic antagonist commonly used in treatment of coronary artery disease (CAD)."5.27Population Pharmacokinetic Analysis of Bisoprolol in Patients with Stable Coronary Artery Disease. ( Deljanin-Ilic, M; Jankovic, SM; Jevtovic-Stoimenov, T; Milovanovic, JR; Nikolic, ML; Nikolic, VN; Stojanovic, SS; Stokanovic, D; Zivanovic, S, 2018)
"We evaluated change in resting heart rate (RHR) and its impact on prognosis in Chinese coronary artery disease (CAD) patients treated with bisoprolol, and also assessed drug safety and tolerability."5.27Occurrence of composite cardiac endpoints with change in resting heart rate among Chinese patients with coronary artery disease: Chinese cohort from the real-world BISO-CAD study. ( Cao, F; Chen, X; Chen, Y; Fu, G; Gan, X; Huang, S; Li, J; Liu, H; Liu, S; Liu, W; Lv, Z; Ma, T; Wang, N; Xu, D; Xu, H; Yang, M; Yang, T; Yang, X; Yang, Y; Yuan, Y; Zheng, Q; Zhou, X, 2018)
" This study assessed the effectiveness and tolerability of bisoprolol/perindopril (Bis/Per) single-pill combination (SPC) in Russian patients with hypertension and coronary artery disease (CAD) treated in routine clinical practice."4.02Effectiveness and Tolerability of the Single-Pill Combination of Bisoprolol and Perindopril in Patients with Arterial Hypertension and Stable Coronary Artery Disease in Daily Clinical Practice: The STYLE Study. ( Boytsov, SA; Burtsev, YP; Karpov, YA; Khomitskaya, YV, 2021)
"Bisoprolol can effectively reduce RHR in Asian CAD patients with comorbid hypertension and hence, improve CCCO without affecting their blood pressure."3.96Resting heart rate control and prognosis in coronary artery disease patients with hypertension previously treated with bisoprolol: a sub-group analysis of the BISO-CAD study. ( Chen, XP; Chen, YD; Fu, GS; Huang, SA; Kim, DS; Kim, TH; Liu, SW; Ma, TR; Pham, VN; Truong, BQ; Yang, XC; Yang, Y, 2020)
"to compare the antianginal and pulse slowing effects, the impact on the ectopic myocardial activity as well as the safety of the treatment with beta - adrenoblocker bisoprolol, calcium antagonist verapamil and the combination of bisoprolol with amlodipine in patients with stable angina (SA) and bronchial asthma (BA)."3.91[Possibilities of cardioselective beta - blocker bisoprolol therapy in patients having coronary artery disease and bronchial asthma]. ( Grigorieva, NY; Ilyushina, TP; Yashina, EM, 2019)
"To evaluate the association between decrease in resting heart rate (RHR) and occurrence of composite cardiac clinical outcomes in coronary artery disease (CAD) patients after bisoprolol treatment."3.88Heart rate control is associated with reduced cardiovascular events in Asian patients with coronary artery disease treated with bisoprolol (BISO-CAD): results from a multi-national, real-world experience. ( Chen, X; Chen, Y; Fu, G; Huang, S; Kim, DS; Kim, TH; Liu, S; Ma, T; Nguyen Pham, V; Quang Truong, B; Yang, X; Yang, Y, 2018)
"We compared the efficacy of perioperative ivabradine, bisoprolol, or both for prevention of postoperative atrial fibrillation (AF) in patients undergoing coronary artery bypass grafting (CABG)."3.83Atrial Fibrillation After Coronary Artery Bypass Surgery: Can Ivabradine Reduce Its Occurrence? ( Abdel-Salam, Z; Nammas, W, 2016)
"Bisoprolol was started at 1."2.76Comparison of effectiveness of carvedilol versus bisoprolol for prevention of postdischarge atrial fibrillation after coronary artery bypass grafting in patients with heart failure. ( Arisi, G; Caminiti, G; Iellamo, F; Madonna, M; Marazzi, G; Massaro, R; Righi, D; Rosano, GM; Volterrani, M, 2011)
"We examined 99 patients with coronary atherosclerosis either with stable angina without history of vascular events or more than 6 month after myocardial infarction and/or coronary intervention."1.46[Effect of Bisoprolol on Heart Rate Variability in Patients With Coronary Atherosclerosis: Dependence on Polymorphisms of -1 Adrenergic Receptor Gene]. ( Bunova, SS; Nelidova, AV; Usacheva, EV; Voronina, EN; Zamakhina, OV, 2017)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (13.33)29.6817
2010's10 (66.67)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Chen, YD1
Yang, XC1
Pham, VN1
Huang, SA1
Fu, GS1
Chen, XP1
Truong, BQ1
Yang, Y3
Liu, SW1
Ma, TR1
Kim, DS2
Kim, TH2
Grigorieva, NY1
Ilyushina, TP1
Yashina, EM1
Foley, M1
Rajkumar, CA1
Shun-Shin, M1
Ganesananthan, S1
Seligman, H1
Howard, J1
Nowbar, AN1
Keeble, TR1
Davies, JR1
Tang, KH1
Gerber, R1
O'Kane, P1
Sharp, ASP1
Petraco, R1
Malik, IS1
Nijjer, S1
Sen, S1
Francis, DP1
Al-Lamee, R1
Boytsov, SA1
Burtsev, YP1
Khomitskaya, YV1
Karpov, YA1
Nikolic, VN1
Jankovic, SM1
Deljanin-Ilic, M1
Stojanovic, SS1
Nikolic, ML1
Zivanovic, S1
Stokanovic, D1
Jevtovic-Stoimenov, T1
Milovanovic, JR1
Bunova, SS1
Zamakhina, OV1
Usacheva, EV1
Nelidova, AV1
Voronina, EN1
Chen, Y2
Yang, X2
Nguyen Pham, V1
Huang, S2
Fu, G2
Chen, X3
Quang Truong, B1
Liu, S2
Ma, T2
Xu, H1
Zhou, X1
Lv, Z1
Yang, M1
Gan, X1
Xu, D1
Cao, F1
Liu, H1
Li, J1
Zheng, Q1
Wang, N1
Yuan, Y1
Liu, W1
Yang, T1
Muster, V1
Wallner, M1
Schmidt, A1
Kapl, M1
von Lewinski, F1
Rainer, P1
Reittner, P1
Tillich, M1
Brader, P1
Szolar, DH1
von Lewinski, D1
Ignjatovic, V1
Pavlovic, S1
Miloradovic, V1
Andjelkovic, N1
Davidovic, G1
Djurdjevic, P1
Stolic, R1
Iric-Cupic, V1
Simic, I1
Ignjatovic, VD1
Petrovic, N1
Smiljanic, Z1
Zdravkovic, V1
Simovic, S1
Jovanovic, D1
Nesic, J1
Tagliamonte, E1
Cirillo, T1
Rigo, F1
Astarita, C1
Coppola, A1
Romano, C1
Capuano, N1
Abdel-Salam, Z1
Nammas, W1
Allen LaPointe, NM1
Zhou, Y1
Stafford, JA1
Hernandez, AF1
Kramer, JM1
Anstrom, KJ1
Marazzi, G1
Iellamo, F1
Volterrani, M1
Caminiti, G1
Madonna, M1
Arisi, G1
Massaro, R1
Righi, D1
Rosano, GM1
Kolasińska-Kloch, W1
Furgała, A1
Laskiewicz, J1
Dobrek, L1
Thor, PJ1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Defining a Gold Standard for Ischaemia: Effects of Interventional Revascularisation Versus Optimum Medical Therapy on Exercise Capacity in Patients With Stable Coronary Artery Disease[NCT02062593]230 participants (Actual)Interventional2013-12-31Completed
Multicenter Observational Open Program. Assessment of the Efficacy and Tolerability of the Fixed-dose Combination of Bisoprolol/Perindopril in Patients With Arterial Hypertension and Stable CAD in Daily Clinical Practice (STYLE)[NCT03730116]1,909 participants (Actual)Observational2018-11-14Completed
Effects of Selective and Nonselective Beta-blockade on Platelet Aggregation in Patients With Acute Coronary Syndrome[NCT02809820]Phase 4100 participants (Actual)Interventional2016-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Exercise Time on Treadmill

(NCT02062593)
Timeframe: 6 weeks

Interventionseconds (Mean)
Coronary Angioplasty and Optimum Medical Therapy28.4
Sham Procedure and Optimum Medical Therapy11.8

Changes in the Mean Office Diastolic BP Levels (in mm Hg) in the Sitting Position

Changes in the mean office diastolic BP levels (in mm Hg) in the sitting position among the patints with HT and CAD recieving bis/perindopril FDC (NCT03730116)
Timeframe: 3 months

Interventionmm Hg (Mean)
Mean Office DBP Changes Between v3 vs Baseline15.9

Efficacy of Bisoprolol/Perindopril FDC in Patients With HT and Stable CAD in Everyday Practice Regarding the BP: % of Patients Achieving Target Levels

The percentage of the patients achieved the target levels of clinical BP among included patients ( SBP < 140 mm Hg and DBP < 90 mm Hg) with HT and stable CAD recieving Bisoprolol/Perindopril FDC (NCT03730116)
Timeframe: 3 month

InterventionParticipants (Count of Participants)
the Patients With HT and Concomitant Stable CAD1640

Efficacy of Bisoprolol/Perindopril FDC in Patients With HT and Stable CAD in Everyday Practice: # of Angina Attacks

Average decrease of the number of angina attacks in patients with HT and stable CAD who recieved the bisoprolol/perindopril FDC (NCT03730116)
Timeframe: 3 month

Interventionnumber of angina attacks per week (Mean)
the Patients With HT and Concomitant Stable CAD-3.2

Good and Moderate Adherence to Bisoprolol/Perindopril FDC Therapy in Patients With HT and Stable CAD in Everyday Practice

"Percentage of the patients with definite answer on question from questionnaire regarding adherence; (Compliance evaluation test - 6 questions tes; Answer No to all questions: good compliance; Answer Yes to 1-2 questions: minor compliance; Answer Yes to 3 or more questions: noncompliance)" (NCT03730116)
Timeframe: 3 month

InterventionParticipants (Count of Participants)
the Patients With HT and Concomitant Stable CAD1827

Impact on the Quality of Life of Bisoprolol/Perindopril FDC in Patients With HT and Stable CAD in Everyday Practice: VAS

Changes of the score in the visual analog scale (VAS) to assess the wellbeing; (minimum score 0 mm and maximum score 100 mm) among patients with HT and CAD recieving biso/perindopril FDC (NCT03730116)
Timeframe: 3 month

Interventionunits on a scale - mm (Mean)
the Patients With HT and Concomitant Stable CAD35.1

The Mean SBP Changes (mm Hg) at the Visit 3 vs. Baseline

Changes in the mean office systolic BP levels (in mm Hg) in the sitting position (NCT03730116)
Timeframe: 3 months

Interventionmm Hg (Mean)
Mean of SBP Changes31.5

Trials

5 trials available for bisoprolol and Arteriosclerosis, Coronary

ArticleYear
Achieving Optimal Medical Therapy: Insights From the ORBITA Trial.
    Journal of the American Heart Association, 2021, 02-02, Volume: 10, Issue:3

    Topics: Amlodipine; Bisoprolol; Cardiovascular Agents; Coronary Angiography; Coronary Artery Disease; Dose-R

2021
Population Pharmacokinetic Analysis of Bisoprolol in Patients with Stable Coronary Artery Disease.
    European journal of drug metabolism and pharmacokinetics, 2018, Volume: 43, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Bisoprolol; Coronary Artery Disease; Female; Humans; Male;

2018
Occurrence of composite cardiac endpoints with change in resting heart rate among Chinese patients with coronary artery disease: Chinese cohort from the real-world BISO-CAD study.
    Current medical research and opinion, 2018, Volume: 34, Issue:11

    Topics: Acute Coronary Syndrome; Adrenergic beta-1 Receptor Antagonists; Aged; Bisoprolol; China; Cohort Stu

2018
Ivabradine and Bisoprolol on Doppler-derived Coronary Flow Velocity Reserve in Patients with Stable Coronary Artery Disease: Beyond the Heart Rate.
    Advances in therapy, 2015, Volume: 32, Issue:8

    Topics: Aged; Benzazepines; Bisoprolol; Blood Flow Velocity; Cardiovascular Agents; Coronary Artery Disease;

2015
Comparison of effectiveness of carvedilol versus bisoprolol for prevention of postdischarge atrial fibrillation after coronary artery bypass grafting in patients with heart failure.
    The American journal of cardiology, 2011, Jan-15, Volume: 107, Issue:2

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Bisoprolol; Carbazoles

2011

Other Studies

10 other studies available for bisoprolol and Arteriosclerosis, Coronary

ArticleYear
Resting heart rate control and prognosis in coronary artery disease patients with hypertension previously treated with bisoprolol: a sub-group analysis of the BISO-CAD study.
    Chinese medical journal, 2020, May-20, Volume: 133, Issue:10

    Topics: Aged; Bisoprolol; China; Coronary Artery Disease; Heart Rate; Humans; Hypertension; Middle Aged; Pro

2020
[Possibilities of cardioselective beta - blocker bisoprolol therapy in patients having coronary artery disease and bronchial asthma].
    Terapevticheskii arkhiv, 2019, Sep-15, Volume: 91, Issue:9

    Topics: Adrenergic beta-Antagonists; Amlodipine; Asthma; Bisoprolol; Coronary Artery Disease; Humans

2019
Effectiveness and Tolerability of the Single-Pill Combination of Bisoprolol and Perindopril in Patients with Arterial Hypertension and Stable Coronary Artery Disease in Daily Clinical Practice: The STYLE Study.
    Advances in therapy, 2021, Volume: 38, Issue:6

    Topics: Aged; Antihypertensive Agents; Bisoprolol; Blood Pressure; Coronary Artery Disease; Drug Combination

2021
[Effect of Bisoprolol on Heart Rate Variability in Patients With Coronary Atherosclerosis: Dependence on Polymorphisms of -1 Adrenergic Receptor Gene].
    Kardiologiia, 2017, Volume: 57, Issue:3

    Topics: Adrenergic beta-Antagonists; Bisoprolol; Coronary Artery Disease; Heart Rate; Humans; Polymorphism,

2017
Heart rate control is associated with reduced cardiovascular events in Asian patients with coronary artery disease treated with bisoprolol (BISO-CAD): results from a multi-national, real-world experience.
    Current medical research and opinion, 2018, Volume: 34, Issue:2

    Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Asian People; Bisoprolol; China; Coronary Artery Disea

2018
Heart rate-reducing therapy with add-on ivabradine and bisoprolol before coronary computed tomographic angiography in a fast-track ambulatory setting.
    The Journal of international medical research, 2018, Volume: 46, Issue:6

    Topics: Aged; Bisoprolol; Cardiovascular Agents; Clinical Protocols; Computed Tomography Angiography; Corona

2018
Influence of Different β-Blockers on Platelet Aggregation in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy.
    Journal of cardiovascular pharmacology and therapeutics, 2016, Volume: 21, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Aspirin; Bisoprolol; Carbazoles; Carvedilol; Clopidog

2016
Atrial Fibrillation After Coronary Artery Bypass Surgery: Can Ivabradine Reduce Its Occurrence?
    Journal of cardiovascular electrophysiology, 2016, Volume: 27, Issue:6

    Topics: Action Potentials; Adrenergic beta-1 Receptor Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibr

2016
Association between mortality and persistent use of beta blockers and angiotensin-converting enzyme inhibitors in patients with left ventricular systolic dysfunction and coronary artery disease.
    The American journal of cardiology, 2009, Jun-01, Volume: 103, Issue:11

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Bisoprolol; Carb

2009
Heart rate variability in patients with coronary artery disease receiving bisoprolol.
    Acta cardiologica, 2004, Volume: 59, Issue:2

    Topics: Adrenergic beta-Antagonists; Bisoprolol; Circadian Rhythm; Coronary Artery Disease; Female; Heart Ra

2004