bismuth-subsalicylate and Gastrointestinal-Hemorrhage

bismuth-subsalicylate has been researched along with Gastrointestinal-Hemorrhage* in 3 studies

Trials

1 trial(s) available for bismuth-subsalicylate and Gastrointestinal-Hemorrhage

ArticleYear
Treatment of Helicobacter pylori reduces the rate of rebleeding in peptic ulcer disease.
    Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:11

    We evaluated whether therapy designed to eradicate Helicobacter pylori infection resulted in a reduction in rebleeding in patients with peptic ulcer disease. Patients presenting because of major upper gastrointestinal hemorrhage from peptic ulcer and whose ulcers healed in a study in which they were randomized to receive ranitidine alone or triple therapy plus ranitidine were followed up regularly with endoscopy. No maintenance anti-ulcer therapy was given after ulcer healing.. Patients received ranitidine, 300 mg, or ranitidine plus triple therapy. Triple therapy consisted of tetracycline, 2 g; metronidazole, 750 mg; and bismuth subsalicylate, 5 or 8 tablets (151 mg bismuth per tablet), and was administered for the first 2 weeks of treatment; ranitidine therapy was continued until the ulcer had healed or 16 weeks had elapsed. After ulcer healing, no maintenance antiulcer therapy was given. Development of ulcer recurrence with or without recurrent upper gastrointestinal bleeding was evaluated.. Thirty-one patients with major upper gastrointestinal bleeding from peptic ulcer were studied; 17 received triple therapy and 14 ranitidine alone. Major rebleeding occurred significantly (p = 0.031) more often in those in the ranitidine group (28.6%), compared with none (0%) in the triple therapy group.. Eradication of H. pylori infection reduces the rate of ulcer recurrence and rebleeding in complicated ulcer disease.

    Topics: Adult; Aged; Bismuth; Drug Therapy, Combination; Follow-Up Studies; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Male; Metronidazole; Middle Aged; Organometallic Compounds; Peptic Ulcer; Prospective Studies; Ranitidine; Recurrence; Salicylates; Tetracycline

1993

Other Studies

2 other study(ies) available for bismuth-subsalicylate and Gastrointestinal-Hemorrhage

ArticleYear
Black heme-positive stools without gastrointestinal hemorrhage.
    The Journal of pediatrics, 1982, Volume: 100, Issue:3

    Topics: Bismuth; Color; False Positive Reactions; Feces; Female; Gastrointestinal Hemorrhage; Heme; Humans; Infant; Organometallic Compounds; Salicylates

1982
Comparative evaluation of gastrointestinal blood loss in the feces of rats following Pepto-Bismol liquid and aspirin administration.
    Life sciences, 1980, Apr-21, Volume: 26, Issue:16

    Topics: Animals; Aspirin; Bismuth; Feces; Gastrointestinal Hemorrhage; Male; Occult Blood; Organometallic Compounds; Rats; Salicylates

1980