bisindolylmaleimide i has been researched along with Ovarian Neoplasms in 5 studies
bisindolylmaleimide I: a bis(indolyl)maleimide
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Verapamil was also inhibitory, indicating that gonadotropins activate calcium influx via L-type voltage-dependent calcium channels." | 1.36 | Gonadotropin-induced ovarian cancer cell migration and proliferation require extracellular signal-regulated kinase 1/2 activation regulated by calcium and protein kinase C{delta}. ( Baxter, RC; Bolitho, C; Marsh, DJ; Mertens-Walker, I, 2010) |
| "Endothelin 1 (ET-1) is produced in ovarian cancer cell lines and has been shown to act through ET(A) receptors as an autocrine growth factor to promote tumor cell proliferation in vitro." | 1.30 | Activation of mitogenic signaling by endothelin 1 in ovarian carcinoma cells. ( Bagnato, A; Catt, KJ; Di Castro, V; Tecce, R, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mertens-Walker, I | 1 |
| Bolitho, C | 1 |
| Baxter, RC | 1 |
| Marsh, DJ | 1 |
| Kim, KY | 1 |
| Choi, KC | 1 |
| Auersperg, N | 1 |
| Leung, PC | 1 |
| D'Souza, T | 1 |
| Indig, FE | 1 |
| Morin, PJ | 1 |
| Bagnato, A | 1 |
| Tecce, R | 1 |
| Di Castro, V | 1 |
| Catt, KJ | 1 |
| Thant, AA | 1 |
| Nawa, A | 1 |
| Kikkawa, F | 1 |
| Ichigotani, Y | 1 |
| Zhang, Y | 1 |
| Sein, TT | 1 |
| Amin, AR | 1 |
| Hamaguchi, M | 1 |
5 other studies available for bisindolylmaleimide i and Ovarian Neoplasms
| Article | Year |
|---|---|
Gonadotropin-induced ovarian cancer cell migration and proliferation require extracellular signal-regulated kinase 1/2 activation regulated by calcium and protein kinase C{delta}.
Topics: Acetophenones; Benzopyrans; Calcium; Calcium Channels, L-Type; Cell Line, Tumor; Cell Movement; Cell | 2010 |
Mechanism of gonadotropin-releasing hormone (GnRH)-I and -II-induced cell growth inhibition in ovarian cancer cells: role of the GnRH-I receptor and protein kinase C pathway.
Topics: Adenocarcinoma; Cell Proliferation; Enzyme Activation; Enzyme Inhibitors; Female; Gonadotropin-Relea | 2006 |
Phosphorylation of claudin-4 by PKCepsilon regulates tight junction barrier function in ovarian cancer cells.
Topics: Cell Line, Tumor; Claudin-4; Female; Humans; Indoles; Maleimides; Membrane Proteins; Mutation; Ovari | 2007 |
Activation of mitogenic signaling by endothelin 1 in ovarian carcinoma cells.
Topics: Benzoquinones; Blotting, Northern; Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion Molec | 1997 |
Fibronectin activates matrix metalloproteinase-9 secretion via the MEK1-MAPK and the PI3K-Akt pathways in ovarian cancer cells.
Topics: Androstadienes; Butadienes; Chromones; Enzyme Inhibitors; Female; Fibronectins; Flavonoids; Humans; | 2000 |