bisindolylmaleimide i has been researched along with Obesity in 3 studies
bisindolylmaleimide I: a bis(indolyl)maleimide
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Moreover, the mRNA expression of ET-1 was significantly increased in cultured HAECs in response to acute (< 24 h) and chronic (12-16 days) treatments with palmitic acid (PA), one of the most abundant saturated fatty acids in obesity." | 3.88 | Palmitic Acid Increases Endothelin-1 Expression in Vascular Endothelial Cells through the Induction of Endoplasmic Reticulum Stress and Protein Kinase C Signaling. ( Wang, X; Xu, L; Yang, XC; Zhang, J; Zhao, WS, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, J | 1 |
| Zhao, WS | 1 |
| Wang, X | 1 |
| Xu, L | 1 |
| Yang, XC | 1 |
| Park, JY | 1 |
| Kim, YM | 2 |
| Song, HS | 1 |
| Park, KY | 1 |
| Kim, MS | 1 |
| Pak, YK | 1 |
| Lee, IK | 1 |
| Lee, JD | 1 |
| Park, SJ | 1 |
| Lee, KU | 1 |
| Fluckey, JD | 1 |
| Cortright, RN | 1 |
| Tapscott, E | 1 |
| Koves, T | 1 |
| Smith, L | 1 |
| Pohnert, S | 1 |
| Dohm, GL | 1 |
3 other studies available for bisindolylmaleimide i and Obesity
| Article | Year |
|---|---|
Palmitic Acid Increases Endothelin-1 Expression in Vascular Endothelial Cells through the Induction of Endoplasmic Reticulum Stress and Protein Kinase C Signaling.
Topics: Animals; Cells, Cultured; Diet, High-Fat; Endoplasmic Reticulum Stress; Endothelial Cells; Endotheli | 2018 |
Oleic acid induces endothelin-1 expression through activation of protein kinase C and NF-kappa B.
Topics: Cells, Cultured; Endothelin-1; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Gene Exp | 2003 |
Active involvement of PKC for insulin-mediated rates of muscle protein synthesis in Zucker rats.
Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Indoles; Insulin; Maleimides; Muscle Proteins; Muscle | 2004 |