bisindolylmaleimide i has been researched along with Muscle Relaxation in 8 studies
bisindolylmaleimide I: a bis(indolyl)maleimide
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
Excerpt | Relevance | Reference |
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"To examine the role of contractile agonist-induced activation of protein kinase C (PKC) in functional antagonism of airway smooth muscle contraction by beta-adrenoceptor agonists, we examined the effects of the specific PKC-inhibitor GF 109203X (2-[1-(3-dimethylaminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl) maleimide) on isoprenaline-induced relaxation of bovine tracheal smooth muscle contracted by various concentrations of methacholine and histamine." | 3.73 | Potentiation of beta-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C. ( Boterman, M; Elzinga, CR; Eppens, PB; Meurs, H; Wagemakers, D; Zaagsma, J, 2005) |
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 6 (75.00) | 29.6817 |
2010's | 2 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Maki, T | 1 |
Kajioka, S | 2 |
Itsumi, M | 1 |
Kareman, E | 1 |
Lee, K | 1 |
Shiota, M | 1 |
Eto, M | 1 |
Shahab, N | 1 |
Seki, N | 1 |
Naito, S | 2 |
Takahashi, R | 1 |
Nishimura, J | 1 |
Hirano, K | 1 |
Kanaide, H | 1 |
Oostendorp, J | 1 |
Obels, PP | 1 |
Terpstra, AR | 1 |
Nelemans, SA | 1 |
Zaagsma, J | 2 |
Boterman, M | 1 |
Elzinga, CR | 1 |
Wagemakers, D | 1 |
Eppens, PB | 1 |
Meurs, H | 1 |
Angulo, J | 1 |
Cuevas, P | 1 |
Fernández, A | 1 |
Allona, A | 1 |
Moncada, I | 1 |
Martín-Morales, A | 1 |
La Fuente, JM | 1 |
de Tejada, IS | 1 |
Patel, CA | 1 |
Rattan, S | 1 |
Kawabata, A | 1 |
Kuroda, R | 1 |
Kuroki, N | 1 |
Nishikawa, H | 1 |
Kawai, K | 1 |
Araki, H | 1 |
8 other studies available for bisindolylmaleimide i and Muscle Relaxation
Article | Year |
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Mirabegron induces relaxant effects via cAMP signaling-dependent and -independent pathways in detrusor smooth muscle.
Topics: Acetanilides; Adenylyl Cyclase Inhibitors; Aged; Amides; Animals; Carbachol; Cyclic AMP; Female; Hum | 2019 |
Functional role of muscarinic receptor subtypes in calcium sensitization and their contribution to rho-kinase and protein kinase C pathways in contraction of human detrusor smooth muscle.
Topics: Amides; Calcium; Carbachol; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Maleimides; Mus | 2012 |
Modulation of Ca2+ sensitivity regulates contractility of rabbit corpus cavernosum smooth muscle.
Topics: Adrenergic alpha-Agonists; Amides; Animals; Calcium; Enzyme Inhibitors; In Vitro Techniques; Indoles | 2003 |
Modulation of beta2- and beta3-adrenoceptor-mediated relaxation of rat oesophagus smooth muscle by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Dose-Response Relationship, Drug; Drug Synergism; Esophagus; E | 2004 |
Potentiation of beta-adrenoceptor function in bovine tracheal smooth muscle by inhibition of protein kinase C.
Topics: Adrenergic beta-Agonists; Animals; Cattle; Colforsin; Dose-Response Relationship, Drug; Drug Synergi | 2005 |
Enhanced thromboxane receptor-mediated responses and impaired endothelium-dependent relaxation in human corpus cavernosum from diabetic impotent men: role of protein kinase C activity.
Topics: Alprostadil; Bridged Bicyclo Compounds, Heterocyclic; Diabetes Mellitus; Endothelium; Erectile Dysfu | 2006 |
Cellular regulation of basal tone in internal anal sphincter smooth muscle by RhoA/ROCK.
Topics: ADP Ribose Transferases; Amides; Anal Canal; Animals; Botulinum Toxins; Carrier Proteins; Cells, Cul | 2007 |
Characterization of the protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle.
Topics: Androstadienes; Animals; Apamin; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug | 2000 |