bisindolylmaleimide i has been researched along with Diabetic Retinopathy in 4 studies
bisindolylmaleimide I: a bis(indolyl)maleimide
Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Increased expression of endothelin-1 (ET-1) is associated with diabetic retinopathy and vasculopathy, although the molecular explanation has not been defined." | 3.72 | Role of protein kinase C on the expression of platelet-derived growth factor and endothelin-1 in the retina of diabetic rats and cultured retinal capillary pericytes. ( Bornfeldt, KE; Isshiki, K; King, GL; Ma, RC; Park, JY; Rauniyar, RK; Sotiropoulos, KB; Yokota, T, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, M | 1 |
| Zhou, M | 1 |
| Cai, X | 1 |
| Zhou, Y | 1 |
| Jiang, X | 1 |
| Luo, Y | 1 |
| Hu, Y | 1 |
| Qiu, R | 1 |
| Wu, Y | 1 |
| Zhang, Y | 1 |
| Xiong, Y | 1 |
| Yokota, T | 1 |
| Ma, RC | 1 |
| Park, JY | 1 |
| Isshiki, K | 1 |
| Sotiropoulos, KB | 1 |
| Rauniyar, RK | 1 |
| Bornfeldt, KE | 1 |
| King, GL | 1 |
| Xu, X | 2 |
| Zhu, Q | 2 |
| Xia, X | 2 |
| Zhang, S | 1 |
| Gu, Q | 2 |
| Luo, D | 1 |
| Ho, PC | 1 |
4 other studies available for bisindolylmaleimide i and Diabetic Retinopathy
| Article | Year |
|---|---|
VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Intercellular Adhesio | 2022 |
Role of protein kinase C on the expression of platelet-derived growth factor and endothelin-1 in the retina of diabetic rats and cultured retinal capillary pericytes.
Topics: Animals; Becaplermin; Capillaries; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retino | 2003 |
Blood-retinal barrier breakdown induced by activation of protein kinase C via vascular endothelial growth factor in streptozotocin-induced diabetic rats.
Topics: Animals; Blood-Retinal Barrier; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetic Re | 2004 |
Role of protein kinase C on the alteration of retinal endothelin-1 in streptozotocin-induced diabetic rats.
Topics: Animals; Cell Membrane; Cytosol; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dose-Respons | 2005 |