bisindolylmaleimide i has been researched along with Breast Neoplasms in 11 studies
bisindolylmaleimide I: a bis(indolyl)maleimide
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this paper the signal transduction pathways evoked by bradykinin (BK) in MCF-7 breast cancer cells were investigated." | 3.73 | Protein kinase C (PKC)-delta/-epsilon mediate the PKC/Akt-dependent phosphorylation of extracellular signal-regulated kinases 1 and 2 in MCF-7 cells stimulated by bradykinin. ( Greco, S; Marsigliante, S; Storelli, C, 2006) |
| "Human-derived MCF-7 breast cancer cells that lack constitutive expression of PKC-alpha or PKC-theta at detectable levels were transfected with full-length PKC-alpha or PKC-theta genes driven by the ecdysone promoter." | 1.31 | Regulation of MDR1 promoter activity in human breast carcinoma cells by protein kinase C isozymes alpha and theta. ( Gant, TW; Gescher, A; Gill, PK, 2001) |
| "Staurosporine was the most potent and the bisindolylmaleimides RO 31 8220 and GF 109203X the least potent cytostatic agents." | 1.29 | Comparison of staurosporine and four analogues: their effects on growth, rhodamine 123 retention and binding to P-glycoprotein in multidrug-resistant MCF-7/Adr cells. ( Budworth, J; Davies, R; Ferry, DR; Gant, TW; Gescher, A; Malkhandi, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Varga, K | 1 |
| Pászty, K | 1 |
| Padányi, R | 1 |
| Hegedűs, L | 1 |
| Brouland, JP | 1 |
| Papp, B | 1 |
| Enyedi, A | 1 |
| Chang, HT | 1 |
| Chou, CT | 1 |
| Kuo, DH | 1 |
| Shieh, P | 1 |
| Jan, CR | 1 |
| Liang, WZ | 1 |
| Chen, HW | 1 |
| Chao, CY | 1 |
| Lin, LL | 1 |
| Lu, CY | 1 |
| Liu, KL | 1 |
| Lii, CK | 1 |
| Li, CC | 1 |
| Garcia-Fernandez, MO | 1 |
| Schally, AV | 1 |
| Varga, JL | 1 |
| Groot, K | 1 |
| Busto, R | 1 |
| Pettersson, F | 1 |
| Couture, MC | 1 |
| Hanna, N | 1 |
| Miller, WH | 1 |
| Muscella, A | 1 |
| Storelli, C | 2 |
| Marsigliante, S | 2 |
| Greco, S | 1 |
| Torricelli, C | 1 |
| Fortino, V | 1 |
| Capurro, E | 1 |
| Valacchi, G | 1 |
| Pacini, A | 1 |
| Muscettola, M | 1 |
| Soucek, K | 1 |
| Maioli, E | 1 |
| Budworth, J | 1 |
| Davies, R | 1 |
| Malkhandi, J | 1 |
| Gant, TW | 2 |
| Ferry, DR | 1 |
| Gescher, A | 2 |
| Gill, PK | 1 |
| Sliva, D | 1 |
| English, D | 1 |
| Lyons, D | 1 |
| Lloyd, FP | 1 |
11 other studies available for bisindolylmaleimide i and Breast Neoplasms
| Article | Year |
|---|---|
Histone deacetylase inhibitor- and PMA-induced upregulation of PMCA4b enhances Ca2+ clearance from MCF-7 breast cancer cells.
Topics: Breast Neoplasms; Calcium; Cell Differentiation; Cell Proliferation; Female; Histone Deacetylase Inh | 2014 |
The Mechanism of Ca(2+) Movement in the Involvement of Baicalein-Induced Cytotoxicity in ZR-75-1 Human Breast Cancer Cells.
Topics: Acetylcysteine; Animals; Apoptosis; Boron Compounds; Breast Neoplasms; Calcium; Caspase 3; Caspase 9 | 2015 |
Inhibition of matrix metalloproteinase-9 expression by docosahexaenoic acid mediated by heme oxygenase 1 in 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 human breast cancer cells.
Topics: Adenocarcinoma; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Carcinogens; Cell Movement; | 2013 |
The expression of growth hormone-releasing hormone (GHRH) and its receptor splice variants in human breast cancer lines; the evaluation of signaling mechanisms in the stimulation of cell proliferation.
Topics: Alternative Splicing; Breast Neoplasms; Cell Division; Cyclic AMP; DNA Primers; Female; Growth Hormo | 2003 |
Enhanced retinoid-induced apoptosis of MDA-MB-231 breast cancer cells by PKC inhibitors involves activation of ERK.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Enzyme Activation; Enzyme Inhibitors; Female; Humans; | 2004 |
Atypical PKC-zeta and PKC-iota mediate opposing effects on MCF-7 Na+/K+ATPase activity.
Topics: Androstadienes; Angiotensin II; Animals; Blotting, Western; Breast Neoplasms; Cattle; Cell Line, Tum | 2005 |
Protein kinase C (PKC)-delta/-epsilon mediate the PKC/Akt-dependent phosphorylation of extracellular signal-regulated kinases 1 and 2 in MCF-7 cells stimulated by bradykinin.
Topics: Analysis of Variance; Biological Transport; Bradykinin; Bradykinin B1 Receptor Antagonists; Bradykin | 2006 |
Rottlerin inhibits the nuclear factor kappaB/cyclin-D1 cascade in MCF-7 breast cancer cells.
Topics: Acetophenones; Benzopyrans; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Ce | 2008 |
Comparison of staurosporine and four analogues: their effects on growth, rhodamine 123 retention and binding to P-glycoprotein in multidrug-resistant MCF-7/Adr cells.
Topics: Alkaloids; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Ne | 1996 |
Regulation of MDR1 promoter activity in human breast carcinoma cells by protein kinase C isozymes alpha and theta.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Breast Neoplasms; Cataly | 2001 |
Protein kinase C induces motility of breast cancers by upregulating secretion of urokinase-type plasminogen activator through activation of AP-1 and NF-kappaB.
Topics: Breast Neoplasms; Cell Movement; Chloramphenicol O-Acetyltransferase; DNA-Binding Proteins; Dose-Res | 2002 |