bisindolylmaleimide i has been researched along with Bone Loss, Osteoclastic in 4 studies
bisindolylmaleimide I: a bis(indolyl)maleimide
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the role of PKC in bone resorption further, we have measured calcium release elicited by bone-resorbing hormones from isolated bones incubated with the PKC inhibitors staurosporine (ST) and the more PKC-selective ST analog bisindolylmaleimide I (GF109203X; GF)." | 1.31 | Divergent effects of protein kinase C (PKC) inhibitors staurosporine and bisindolylmaleimide I (GF109203X) on bone resorption. ( Lee, SK; Stern, PH, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, J | 1 |
| Jang, H | 1 |
| Lin, J | 1 |
| Lee, SY | 1 |
| Yao, J | 1 |
| Li, J | 1 |
| Zhou, L | 1 |
| Cheng, J | 1 |
| Chim, SM | 1 |
| Zhang, G | 1 |
| Quinn, JM | 1 |
| Tickner, J | 1 |
| Zhao, J | 1 |
| Xu, J | 1 |
| Berger, CE | 1 |
| Horrocks, BR | 1 |
| Datta, HK | 1 |
| Lee, SK | 1 |
| Stern, PH | 1 |
4 other studies available for bisindolylmaleimide i and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
PKCβ positively regulates RANKL-induced osteoclastogenesis by inactivating GSK-3β.
Topics: Animals; Bone Resorption; Cell Differentiation; Cells, Cultured; Glycogen Synthase Kinase 3; Glycoge | 2014 |
Protein kinase C inhibitor, GF109203X attenuates osteoclastogenesis, bone resorption and RANKL-induced NF-κB and NFAT activity.
Topics: Animals; Bone Resorption; Cell Differentiation; Cell Line; Indoles; Maleimides; Mice; NF-kappa B; NF | 2015 |
cAMP-dependent inhibition is dominant in regulating superoxide production in the bone-resorbing osteoclasts.
Topics: Animals; Bone Resorption; Bucladesine; Cells, Cultured; Cholera Toxin; Cyclic AMP; Dose-Response Rel | 1998 |
Divergent effects of protein kinase C (PKC) inhibitors staurosporine and bisindolylmaleimide I (GF109203X) on bone resorption.
Topics: Animals; Bone and Bones; Bone Resorption; Calcium; Calcium Radioisotopes; Drug Interactions; Enzyme | 2000 |