bisindolylmaleimide i has been researched along with Allodynia in 6 studies
bisindolylmaleimide I: a bis(indolyl)maleimide
| Excerpt | Relevance | Reference |
|---|---|---|
| "And the mechanical allodynia induced by PK2 was prevented by co-administration of TNP-ATP, a selective P2X receptor antagonist." | 1.42 | Prokineticin 2 facilitates mechanical allodynia induced by α,β-methylene ATP in rats. ( Gan, X; Hu, WP; Liu, TT; Qiu, CY; Qu, ZW; Rao, Z; Ren, C, 2015) |
| "The mechanical hyperalgesia caused by ET-1 started 2 hrs after injection, peaked at 5 hrs (PBS, 29 +/- 0." | 1.33 | Mechanical hyperalgesia induced by endothelin-1 in rats is mediated via phospholipase C, protein kinase C, and MAP kinases. ( Calixto, JB; Motta, EM; Rae, GA, 2006) |
| "In contrast, thermal hyperalgesia during spontaneous withdrawal was inhibited by both PKC and gamma inhibitors." | 1.32 | Exaggerated nociceptive responses on morphine withdrawal: roles of protein kinase C epsilon and gamma. ( Allen, CP; Kendig, JJ; Mochly-Rosen, D; Sweitzer, SM; Tjolsen, A; Wong, SM, 2004) |
| "Substance P (SP) is an important neuromediator in the spinal processing of nociceptive afferent information." | 1.31 | Inhibition of spinal protein kinase C blocks substance P-mediated hyperalgesia. ( Hua, XY; Wajima, Z; Yaksh, TL, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ren, C | 1 |
| Qiu, CY | 1 |
| Gan, X | 1 |
| Liu, TT | 1 |
| Qu, ZW | 1 |
| Rao, Z | 1 |
| Hu, WP | 1 |
| Sweitzer, SM | 1 |
| Wong, SM | 1 |
| Tjolsen, A | 1 |
| Allen, CP | 1 |
| Mochly-Rosen, D | 1 |
| Kendig, JJ | 1 |
| Motta, EM | 1 |
| Calixto, JB | 1 |
| Rae, GA | 1 |
| Yashpal, K | 1 |
| Pitcher, GM | 1 |
| Parent, A | 1 |
| Quirion, R | 1 |
| Coderre, TJ | 1 |
| Wajima, Z | 1 |
| Hua, XY | 1 |
| Yaksh, TL | 1 |
| Souza, AL | 1 |
| Moreira, FA | 1 |
| Almeida, KR | 1 |
| Bertollo, CM | 1 |
| Costa, KA | 1 |
| Coelho, MM | 1 |
6 other studies available for bisindolylmaleimide i and Allodynia
| Article | Year |
|---|---|
Prokineticin 2 facilitates mechanical allodynia induced by α,β-methylene ATP in rats.
Topics: Adenosine Triphosphate; Animals; Drug Synergism; Ganglia, Spinal; Gastrointestinal Hormones; Hyperal | 2015 |
Exaggerated nociceptive responses on morphine withdrawal: roles of protein kinase C epsilon and gamma.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Drug Interactions; Enzyme Inhibit | 2004 |
Mechanical hyperalgesia induced by endothelin-1 in rats is mediated via phospholipase C, protein kinase C, and MAP kinases.
Topics: Animals; Endothelin-1; Enzyme Inhibitors; Estrenes; Hyperalgesia; Imidazoles; Indoles; Injections, I | 2006 |
Noxious thermal and chemical stimulation induce increases in 3H-phorbol 12,13-dibutyrate binding in spinal cord dorsal horn as well as persistent pain and hyperalgesia, which is reduced by inhibition of protein kinase C.
Topics: Alkaloids; Analysis of Variance; Animals; Benzophenanthridines; Formaldehyde; Functional Laterality; | 1995 |
Inhibition of spinal protein kinase C blocks substance P-mediated hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Hyperalgesia; Indoles; Injectio | 2000 |
In vivo evidence for a role of protein kinase C in peripheral nociceptive processing.
Topics: Alkaloids; Animals; Benzophenanthridines; Bradykinin; Dose-Response Relationship, Drug; Enzyme Inhib | 2002 |