bisindolylmaleimide i has been researched along with Acute Confusional Senile Dementia in 12 studies
bisindolylmaleimide I: a bis(indolyl)maleimide
| Excerpt | Relevance | Reference |
|---|---|---|
| "Immunostaining of adenosine receptors in the hippocampus and cerebral cortex from necropsies of Alzheimer disease (AD) patients shows that there is a change in the pattern of expression and a redistribution of receptors in these brain areas when compared with samples from controls." | 7.72 | A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation. ( Angulo, E; Canela, EI; Casadó, V; Ferrer, I; Franco, R; Lluis, C; Mallol, J; Viñals, F, 2003) |
| "Immunostaining of adenosine receptors in the hippocampus and cerebral cortex from necropsies of Alzheimer disease (AD) patients shows that there is a change in the pattern of expression and a redistribution of receptors in these brain areas when compared with samples from controls." | 3.72 | A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation. ( Angulo, E; Canela, EI; Casadó, V; Ferrer, I; Franco, R; Lluis, C; Mallol, J; Viñals, F, 2003) |
| " Recent evidence indicates that small tau oligomers are the most relevant toxic aggregate species." | 1.51 | Cornel iridoid glycoside induces autophagy to protect against tau oligomer neurotoxicity induced by the activation of glycogen synthase kinase-3β. ( Li, L; Li, X; Li, Y; Yang, C; Zhang, L, 2019) |
| "Yessotoxin is a marine phycotoxin that induces motor alterations in mice after intraperitoneal injection." | 1.39 | Translocation of PKC by yessotoxin in an in vitro model of Alzheimer's disease with improvement of tau and β-amyloid pathology. ( Alonso, E; Botana, LM; Vale, C; Vieytes, MR, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, C | 1 |
| Li, X | 1 |
| Zhang, L | 2 |
| Li, Y | 1 |
| Li, L | 1 |
| Alonso, E | 1 |
| Vale, C | 1 |
| Vieytes, MR | 1 |
| Botana, LM | 1 |
| Luo, HB | 1 |
| Xia, YY | 1 |
| Shu, XJ | 1 |
| Liu, ZC | 1 |
| Feng, Y | 2 |
| Liu, XH | 1 |
| Yu, G | 1 |
| Yin, G | 1 |
| Xiong, YS | 1 |
| Zeng, K | 1 |
| Jiang, J | 1 |
| Ye, K | 1 |
| Wang, XC | 1 |
| Wang, JZ | 4 |
| Wang, Y | 1 |
| Zhang, JX | 1 |
| Du, XX | 1 |
| Zhao, L | 1 |
| Tian, Q | 2 |
| Zhu, LQ | 2 |
| Wang, SH | 2 |
| Peng, Y | 1 |
| Sun, J | 1 |
| Hon, S | 1 |
| Nylander, AN | 1 |
| Xia, W | 1 |
| Wang, X | 1 |
| Lemere, CA | 1 |
| Zhao, WQ | 1 |
| Ravindranath, L | 1 |
| Mohamed, AS | 1 |
| Zohar, O | 1 |
| Chen, GH | 1 |
| Lyketsos, CG | 1 |
| Etcheberrigaray, R | 1 |
| Alkon, DL | 1 |
| Angulo, E | 1 |
| Casadó, V | 1 |
| Mallol, J | 1 |
| Canela, EI | 1 |
| Viñals, F | 1 |
| Ferrer, I | 1 |
| Lluis, C | 1 |
| Franco, R | 1 |
| Xu, GG | 1 |
| Deng, YQ | 1 |
| Liu, SJ | 1 |
| Li, HL | 1 |
| Shi, HR | 1 |
| Liu, XA | 1 |
| Zhang, Q | 1 |
| Wang, Q | 1 |
| Danenberg, HD | 1 |
| Haring, R | 1 |
| Fisher, A | 1 |
| Pittel, Z | 1 |
| Gurwitz, D | 1 |
| Heldman, E | 1 |
| McLaughlin, M | 1 |
| Breen, KC | 1 |
| Kim, C | 1 |
| Jang, CH | 1 |
| Bang, JH | 1 |
| Jung, MW | 1 |
| Joo, I | 1 |
| Kim, SU | 1 |
| Mook-Jung, I | 1 |
12 other studies available for bisindolylmaleimide i and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Cornel iridoid glycoside induces autophagy to protect against tau oligomer neurotoxicity induced by the activation of glycogen synthase kinase-3β.
Topics: Alzheimer Disease; Animals; Autophagy; Brain; Cell Line, Tumor; Disks Large Homolog 4 Protein; Glyco | 2019 |
Translocation of PKC by yessotoxin in an in vitro model of Alzheimer's disease with improvement of tau and β-amyloid pathology.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Disease Models, Anima | 2013 |
SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination.
Topics: Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Peptides; Androstadienes; Animals; Cerebral | 2014 |
Temporal correlation of the memory deficit with Alzheimer-like lesions induced by activation of glycogen synthase kinase-3.
Topics: Acetylcholine; Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Androstadienes; Animal | 2008 |
L-3-n-butylphthalide improves cognitive impairment and reduces amyloid-beta in a transgenic model of Alzheimer's disease.
Topics: ADAM Proteins; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Be | 2010 |
MAP kinase signaling cascade dysfunction specific to Alzheimer's disease in fibroblasts.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Bradykinin; Calcium Channels; Cyclic AMP Response | 2002 |
A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Aged; Alzheimer Diseas | 2003 |
Prolonged Alzheimer-like tau hyperphosphorylation induced by simultaneous inhibition of phosphoinositol-3 kinase and protein kinase C in N2a cells.
Topics: Alzheimer Disease; Amyloid; Androstadienes; Animals; Cell Line, Tumor; Cell Survival; Dose-Response | 2005 |
17beta-estradiol attenuates glycogen synthase kinase-3beta activation and tau hyperphosphorylation in Akt-independent manner.
Topics: Alzheimer Disease; Androstadienes; Animals; Cell Line, Tumor; Cytoprotection; Enzyme Activation; Enz | 2008 |
Dehydroepiandrosterone (DHEA) increases production and release of Alzheimer's amyloid precursor protein.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Count; Dehydroepiandrosterone; Dose | 1996 |
Protein kinase C activation potentiates the rapid secretion of the amyloid precursor protein from rat cortical synaptosomes.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Fractionation; Cerebral Cortex; Det | 1999 |
Amyloid precursor protein processing is separately regulated by protein kinase C and tyrosine kinase in human astrocytes.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Astrocytes; Brain; Cells, | 2002 |