bisindolylmaleimide i has been researched along with Ache in 10 studies
bisindolylmaleimide I: a bis(indolyl)maleimide
Excerpt | Relevance | Reference |
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"Male Swiss Webster mice exhibited antinociception, hypothermia and Straub tail 3h following a 75mg morphine pellet implantation." | 3.73 | PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice. ( Dewey, WL; Gabra, BH; Javed, RR; Smith, FL; Smith, PA, 2006) |
"In contrast, thermal hyperalgesia during spontaneous withdrawal was inhibited by both PKC and gamma inhibitors." | 1.32 | Exaggerated nociceptive responses on morphine withdrawal: roles of protein kinase C epsilon and gamma. ( Allen, CP; Kendig, JJ; Mochly-Rosen, D; Sweitzer, SM; Tjolsen, A; Wong, SM, 2004) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (20.00) | 18.2507 |
2000's | 6 (60.00) | 29.6817 |
2010's | 2 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Fu, Y | 1 |
Han, J | 1 |
Ishola, T | 1 |
Scerbo, M | 1 |
Adwanikar, H | 1 |
Ramsey, C | 1 |
Neugebauer, V | 1 |
Zhang, L | 1 |
Hammond, DL | 1 |
Silva, MA | 1 |
Klafke, JZ | 1 |
Rossato, MF | 1 |
Gewehr, C | 1 |
Guerra, GP | 1 |
Rubin, MA | 1 |
Ferreira, J | 1 |
Wang, S | 1 |
Dai, Y | 1 |
Kobayashi, K | 1 |
Zhu, W | 1 |
Kogure, Y | 1 |
Yamanaka, H | 1 |
Wan, Y | 1 |
Zhang, W | 1 |
Noguchi, K | 1 |
Smith, FL | 2 |
Javed, RR | 2 |
Elzey, MJ | 1 |
Dewey, WL | 2 |
Sweitzer, SM | 1 |
Wong, SM | 1 |
Tjolsen, A | 1 |
Allen, CP | 1 |
Mochly-Rosen, D | 1 |
Kendig, JJ | 1 |
Smith, PA | 1 |
Gabra, BH | 1 |
Yashpal, K | 1 |
Pitcher, GM | 1 |
Parent, A | 1 |
Quirion, R | 1 |
Coderre, TJ | 1 |
Hua, XY | 1 |
Chen, P | 1 |
Yaksh, TL | 1 |
Souza, AL | 1 |
Moreira, FA | 1 |
Almeida, KR | 1 |
Bertollo, CM | 1 |
Costa, KA | 1 |
Coelho, MM | 1 |
10 other studies available for bisindolylmaleimide i and Ache
Article | Year |
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PKA and ERK, but not PKC, in the amygdala contribute to pain-related synaptic plasticity and behavior.
Topics: Amygdala; Animals; Arthritis; Behavior; Butadienes; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-De | 2008 |
Substance P enhances excitatory synaptic transmission on spinally projecting neurons in the rostral ventromedial medulla after inflammatory injury.
Topics: Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Enzyme Inhibitors; Excita | 2009 |
Role of peripheral polyamines in the development of inflammatory pain.
Topics: Animals; Eflornithine; Gene Expression Regulation, Enzymologic; Indoles; Inflammation; Male; Maleimi | 2011 |
Potentiation of the P2X3 ATP receptor by PAR-2 in rat dorsal root ganglia neurons, through protein kinase-dependent mechanisms, contributes to inflammatory pain.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Gangli | 2012 |
The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA.
Topics: Analgesics; Animals; Brain; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relation | 2003 |
Exaggerated nociceptive responses on morphine withdrawal: roles of protein kinase C epsilon and gamma.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Drug Interactions; Enzyme Inhibit | 2004 |
PKC and PKA inhibitors reinstate morphine-induced behaviors in morphine tolerant mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Body Temperature; Carbazoles; Cyclic AMP-Dependent Pr | 2006 |
Noxious thermal and chemical stimulation induce increases in 3H-phorbol 12,13-dibutyrate binding in spinal cord dorsal horn as well as persistent pain and hyperalgesia, which is reduced by inhibition of protein kinase C.
Topics: Alkaloids; Analysis of Variance; Animals; Benzophenanthridines; Formaldehyde; Functional Laterality; | 1995 |
Inhibition of spinal protein kinase C reduces nerve injury-induced tactile allodynia in neuropathic rats.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibito | 1999 |
In vivo evidence for a role of protein kinase C in peripheral nociceptive processing.
Topics: Alkaloids; Animals; Benzophenanthridines; Bradykinin; Dose-Response Relationship, Drug; Enzyme Inhib | 2002 |