bisdesmoside and Liver-Neoplasms

bisdesmoside has been researched along with Liver-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for bisdesmoside and Liver-Neoplasms

ArticleYear
[Isolation and structural elucidation of a bioactive saponin from tubers of Bolbostemma paniculatum].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:3

    To study the bioactive constituents from tubers of Bolbostemma paniculatum.. Compounds were isolated by extraction and partition as well as several-chromatographic techniques guided with Pyricularia oryzae bioassay method. Their structures were determined on the basis of spectral analysis and chemical evidence.. Bisdesmoside (I) was isolated as active compound causing morphological abnormality of Pyncularia oryzae mycelia and elucidated as 3-0-alpha-L-arabinopyranosyl (1-->2)-beta-D-glucopyranosyl-bayogenin-28-O-beta-D-xylopyranosyl (1-->3)-alpha-L-rhamnopyranosyl (1-->2)-alpha-L-arabinopyranoside.. I is a new natural product and exhibited significant cytotoxicity against cancer cell lines K-562 and BEL-7402, but no hemolytic activity to rabbit erythrocytes.

    Topics: Animals; Biological Assay; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cucurbitaceae; Erythrocytes; Hemolysis; Humans; K562 Cells; Liver Neoplasms; Molecular Conformation; Molecular Structure; Plant Tubers; Plants, Medicinal; Rabbits; Saponins

2006