bisbenzimidazole has been researched along with Scleroderma, Systemic in 2 studies
Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, X | 1 |
| Kiechle, F | 1 |
| Schmitz, A | 1 |
| Guilly, MN | 1 |
| Trask, B | 1 |
| van den Engh, G | 1 |
2 other studies available for bisbenzimidazole and Scleroderma, Systemic
| Article | Year |
|---|---|
Hoechst 33342-induced apoptosis is associated with decreased immunoreactive topoisomerase I and topoisomerase I-DNA complex formation.
Topics: Animals; Apoptosis; Autoantibodies; Benzimidazoles; Bisbenzimidazole; Blotting, Western; Cell Line; | 2001 |
Immunofluorescent labeling of centromeres for flow cytometric analysis.
Topics: Animals; Antibodies; Bisbenzimidazole; Centromere; Chromomycins; Chromosomes; Cricetinae; Cricetulus | 1992 |