bisbenzimidazole has been researched along with Parkinson Disease in 2 studies
Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bossolasco, P | 1 |
| Cova, L | 1 |
| Levandis, G | 1 |
| Diana, V | 1 |
| Cerri, S | 1 |
| Lambertenghi Deliliers, G | 1 |
| Polli, E | 1 |
| Silani, V | 1 |
| Blandini, F | 1 |
| Armentero, MT | 1 |
| Li, J | 1 |
| Fan, Y | 1 |
| Zhang, YN | 1 |
| Sun, DJ | 1 |
| Fu, SB | 1 |
| Ma, L | 1 |
| Jiang, LH | 1 |
| Cui, C | 1 |
| Ding, HF | 1 |
| Yang, J | 1 |
2 other studies available for bisbenzimidazole and Parkinson Disease
| Article | Year |
|---|---|
Noninvasive near-infrared live imaging of human adult mesenchymal stem cells transplanted in a rodent model of Parkinson's disease.
Topics: Administration, Intranasal; Analysis of Variance; Animals; Bisbenzimidazole; Cell Proliferation; Cel | 2012 |
The Raf-1 inhibitor GW5074 and the ERK1/2 pathway inhibitor U0126 ameliorate PC12 cells apoptosis induced by 6-hydroxydopamine.
Topics: Apoptosis; Bisbenzimidazole; Blotting, Western; Butadienes; Cell Survival; Enzyme Inhibitors; Flow C | 2012 |