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bisbenzimidazole and Nerve Degeneration

bisbenzimidazole has been researched along with Nerve Degeneration in 6 studies

Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"We examined the effect of global cerebral ischemia in the rat on the expression of CREB, its transcriptionally active phosphorylated form (pCREB), and the nuclear adaptor protein, CREB binding protein (CBP)."1.31Cyclic AMP response element binding protein (CREB) and CREB binding protein (CBP) in global cerebral ischemia. ( Greenberg, DA; Jin, K; Mao, XO; Simon, RP, 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's5 (83.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Calzà, L1
Fernandez, M1
Giuliani, A1
Pirondi, S1
D'Intino, G1
Manservigi, M1
De Sordi, N1
Giardino, L1
Cervio, E1
Volta, U1
Verri, M1
Boschi, F1
Pastoris, O1
Granito, A1
Barbara, G1
Parisi, C1
Felicani, C1
Tonini, M1
De Giorgio, R1
Bursztajn, S1
DeSouza, R1
McPhie, DL1
Berman, SA1
Shioi, J1
Robakis, NK1
Neve, RL1
Jin, K1
Mao, XO1
Simon, RP1
Greenberg, DA1
Kim, EJ1
Lee, JE1
Kwon, KJ1
Lee, SH1
Moon, CH1
Baik, EJ1
Fiedorowicz, A1
Figiel, I1
Kamińska, B1
Zaremba, M1
Wilk, S1
Oderfeld-Nowak, B1

Other Studies

6 other studies available for bisbenzimidazole and Nerve Degeneration

ArticleYear
Stem cells and nervous tissue repair: from in vitro to in vivo.
    Progress in brain research, 2004, Volume: 146

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Bisbenzimidazole; Blotting, Western; Brain; Bra

2004
Sera of patients with celiac disease and neurologic disorders evoke a mitochondrial-dependent apoptosis in vitro.
    Gastroenterology, 2007, Volume: 133, Issue:1

    Topics: Adult; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Bisbenzimidazo

2007
Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Dec-01, Volume: 18, Issue:23

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Apoptosis; Bisbenzimidazole; Cell Survival; Cereb

1998
Cyclic AMP response element binding protein (CREB) and CREB binding protein (CBP) in global cerebral ischemia.
    Journal of molecular neuroscience : MN, 2001, Volume: 16, Issue:1

    Topics: Animals; Bisbenzimidazole; Blotting, Western; Brain Ischemia; Cell Survival; Cells, Cultured; Cerebr

2001
Differential roles of cyclooxygenase isoforms after kainic acid-induced prostaglandin E(2) production and neurodegeneration in cortical and hippocampal cell cultures.
    Brain research, 2001, Jul-20, Volume: 908, Issue:1

    Topics: Animals; Astrocytes; Bisbenzimidazole; Cells, Cultured; Cerebral Cortex; Coloring Agents; Cyclooxyge

2001
Dentate granule neuron apoptosis and glia activation in murine hippocampus induced by trimethyltin exposure.
    Brain research, 2001, Sep-07, Volume: 912, Issue:2

    Topics: Animals; Apoptosis; Astrocytes; Bisbenzimidazole; Dentate Gyrus; Enzyme Inhibitors; Female; Fluoresc

2001