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bisbenzimidazole and Necrosis

bisbenzimidazole has been researched along with Necrosis in 11 studies

Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
" Salvianic acid A (SA), isolated from the Chinese herbal medicine Salvia miltiorrhiza, is capable of protecting diverse kinds of cells from damage caused by a variety of toxic stimuli."1.33Salvianic acid A protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity. ( Wang, XJ; Xu, JX, 2005)
"Aclarubicin was the fastest acting drug, inducing DNA fragmentation 12 h earlier than doxorubicin, and 24 h earlier than mitoxantrone."1.33Mechanisms of induction of apoptosis by anthraquinone anticancer drugs aclarubicin and mitoxantrone in comparison with doxorubicin: relation to drug cytotoxicity and caspase-3 activation. ( Jedrzejczak, M; Jóźwiak, Z; Kania, K; Koceva-Chyła, A; Skierski, J, 2005)
"Cadmium is a well-known carcinogenic and immunotoxic metal commonly found in cigarette smoke and industrial effluent."1.32Calcium-mediated activation of c-Jun NH2-terminal kinase (JNK) and apoptosis in response to cadmium in murine macrophages. ( Kim, J; Sharma, RP, 2004)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's9 (81.82)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, L1
Wang, H1
Hu, M1
Cao, J1
Chen, D1
Liu, Z1
Kosmider, B1
Anuels, SA1
Evenberg, D1
Zyner, E1
Bahmed, K1
Osiecka, R1
Ochocki, J1
Unal Cevik, I1
Dalkara, T1
Kim, J1
Sharma, RP1
Glawe, C1
Emmrich, J1
Sparmann, G1
Vollmar, B1
Wang, XJ1
Xu, JX1
Koceva-Chyła, A1
Jedrzejczak, M1
Skierski, J1
Kania, K1
Jóźwiak, Z1
Woodgate, A1
MacGibbon, G1
Walton, M1
Dragunow, M1
Eom, YW1
Cho, SH1
Hwang, JS1
Yoon, SB1
Na, DS1
Kang, IJ1
Kang, SS1
Song, WK1
Kim, JH1
Matsuo, A1
Watanabe, A1
Takahashi, T1
Futamura, M1
Mori, S1
Sugiyama, Y1
Takahashi, Y1
Saji, S1
Haidara, K1
Morel, I1
Abalea, V1
Gascon Barre, M1
Denizeau, F1

Other Studies

11 other studies available for bisbenzimidazole and Necrosis

ArticleYear
Oxidative stress and apoptotic changes in primary cultures of rat proximal tubular cells exposed to lead.
    Archives of toxicology, 2009, Volume: 83, Issue:5

    Topics: Animals; Apoptosis; Bisbenzimidazole; Calcium; Catalase; Cell Death; Cell Separation; Cell Survival;

2009
Structure-activity relationship and apoptosis induction in A549 cells by the potential anticancer compound cis-bis(3-aminoflavone)dichloroplatinum(II).
    Arzneimittel-Forschung, 2010, Volume: 60, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Bisbenzimidazole; Cell Line, Tumor; Coloring Agents; Humans; Magne

2010
Intravenously administered propidium iodide labels necrotic cells in the intact mouse brain after injury.
    Cell death and differentiation, 2003, Volume: 10, Issue:8

    Topics: Animals; Apoptosis; Biomarkers; Bisbenzimidazole; Brain; Brain Injuries; Cell Death; Hypoxia-Ischemi

2003
Calcium-mediated activation of c-Jun NH2-terminal kinase (JNK) and apoptosis in response to cadmium in murine macrophages.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 81, Issue:2

    Topics: Animals; Apoptosis; Bisbenzimidazole; Blotting, Western; Cadmium; Calcium; Caspase 3; Caspases; Cell

2004
In vivo characterization of developing chronic pancreatitis in rats.
    Laboratory investigation; a journal of technical methods and pathology, 2005, Volume: 85, Issue:2

    Topics: Amylases; Animals; Apoptosis; Bisbenzimidazole; Carboxylic Ester Hydrolases; Caspases; Chronic Disea

2005
Salvianic acid A protects human neuroblastoma SH-SY5Y cells against MPP+-induced cytotoxicity.
    Neuroscience research, 2005, Volume: 51, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; bcl-2-Associated X Protein; Bisbenzimidazole; Blotting, West

2005
Mechanisms of induction of apoptosis by anthraquinone anticancer drugs aclarubicin and mitoxantrone in comparison with doxorubicin: relation to drug cytotoxicity and caspase-3 activation.
    Apoptosis : an international journal on programmed cell death, 2005, Volume: 10, Issue:6

    Topics: Aclarubicin; Animals; Antineoplastic Agents; Apoptosis; Bisbenzimidazole; Caspase 3; Caspase Inhibit

2005
The toxicity of 6-hydroxydopamine on PC12 and P19 cells.
    Brain research. Molecular brain research, 1999, May-21, Volume: 69, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Aurintricarboxylic Acid; Biological Transport; Bisbenzimi

1999
Rac and p38 kinase mediate 5-lipoxygenase translocation and cell death.
    Biochemical and biophysical research communications, 2001, Jun-01, Volume: 284, Issue:1

    Topics: Animals; Arachidonate 5-Lipoxygenase; Bisbenzimidazole; Cell Death; Cell Line; Chelating Agents; Dos

2001
A simple method for classification of cell death by use of thin layer collagen gel for the detection of apoptosis and/or necrosis after cancer chemotherapy.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Bisbenzimidazole; Cisplatin; Collagen; Eosine Yellowish-(YS); Fluo

2001
Mechanism of tert-butylhydroperoxide induced apoptosis in rat hepatocytes: involvement of mitochondria and endoplasmic reticulum.
    Biochimica et biophysica acta, 2002, Jan-30, Volume: 1542, Issue:1-3

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Bisbenzimidazole; Cells, Cultured; Cytochrome c Grou

2002