bisbenzimidazole has been researched along with Motor Neuron Disease in 1 studies
Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bigini, P | 1 |
| Veglianese, P | 1 |
| Andriolo, G | 1 |
| Cova, L | 1 |
| Grignaschi, G | 1 |
| Caron, I | 1 |
| Daleno, C | 1 |
| Barbera, S | 1 |
| Ottolina, A | 1 |
| Calzarossa, C | 1 |
| Lazzari, L | 1 |
| Mennini, T | 1 |
| Bendotti, C | 1 |
| Silani, V | 1 |
1 other study available for bisbenzimidazole and Motor Neuron Disease
| Article | Year |
|---|---|
Intracerebroventricular administration of human umbilical cord blood cells delays disease progression in two murine models of motor neuron degeneration.
Topics: Amyotrophic Lateral Sclerosis; Animals; Bisbenzimidazole; Cell- and Tissue-Based Therapy; Cytokines; | 2011 |