bisbenzimidazole has been researched along with Malignant Melanoma in 6 studies
Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hoechst 33258 itself was selectively toxic for the MM96E melanoma cell line compared with other cell lines, induced a highly dendritic morphology, increased tyrosinase activity and tyrosinase mRNA but decreased the level of gp75 (TRP-1) mRNA; message for a third pigment gene, Pmel-17, was unchanged." | 5.29 | Transcriptional regulation of differentiation, selective toxicity and ATGCAAAT binding of bisbenzimidazole derivatives in human melanoma cells. ( Danoy, PA; Dong, Y; Dunn, IS; Jacobs, JJ; Kaushal, A; McGregor, K; Michel, J; Sturm, RA; Wong, SS; Zhang, XM, 1994) |
| " Hoechst 33258 itself was selectively toxic for the MM96E melanoma cell line compared with other cell lines, induced a highly dendritic morphology, increased tyrosinase activity and tyrosinase mRNA but decreased the level of gp75 (TRP-1) mRNA; message for a third pigment gene, Pmel-17, was unchanged." | 1.29 | Transcriptional regulation of differentiation, selective toxicity and ATGCAAAT binding of bisbenzimidazole derivatives in human melanoma cells. ( Danoy, PA; Dong, Y; Dunn, IS; Jacobs, JJ; Kaushal, A; McGregor, K; Michel, J; Sturm, RA; Wong, SS; Zhang, XM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wong, SS | 1 |
| Sturm, RA | 1 |
| Michel, J | 1 |
| Zhang, XM | 1 |
| Danoy, PA | 1 |
| McGregor, K | 1 |
| Jacobs, JJ | 1 |
| Kaushal, A | 1 |
| Dong, Y | 1 |
| Dunn, IS | 1 |
| Poot, M | 1 |
| Hiller, KH | 1 |
| Heimpel, S | 1 |
| Schuster, A | 1 |
| Köhler, J | 1 |
| Hoehn, H | 1 |
| Dow, AI | 1 |
| Shafer, SA | 1 |
| Kirkwood, JM | 1 |
| Mascari, RA | 1 |
| Waggoner, AS | 1 |
| Greene, JF | 1 |
| Morgan, CD | 1 |
| Rao, A | 1 |
| Amoss, MS | 1 |
| Arguello, F | 1 |
| Finlay, GJ | 1 |
| Baguley, BC | 1 |
| Freed, WJ | 1 |
| Adinolfi, AM | 1 |
| Laskin, JD | 1 |
| Geller, HM | 1 |
6 other studies available for bisbenzimidazole and Malignant Melanoma
| Article | Year |
|---|---|
Transcriptional regulation of differentiation, selective toxicity and ATGCAAAT binding of bisbenzimidazole derivatives in human melanoma cells.
Topics: Base Sequence; Benzimidazoles; Bisbenzimidazole; Cell Cycle; Cell Differentiation; Cell Survival; Ch | 1994 |
Heterogeneity of bromodeoxyuridine sensitivity of cultured cells from melanoma metastases.
Topics: Bisbenzimidazole; Bromodeoxyuridine; Cell Division; Ethidium; Flow Cytometry; G2 Phase; Genetic Hete | 1995 |
Automatic multiparameter fluorescence imaging for determining lymphocyte phenotype and activation status in melanoma tissue sections.
Topics: Antigens, CD; Automation; Biopsy; Bisbenzimidazole; Color; Fluorescent Dyes; HLA-DR Antigens; Humans | 1996 |
Regression by differentiation in the Sinclair swine model of cutaneous melanoma.
Topics: Animals; Bisbenzimidazole; Cell Differentiation; Disease Models, Animal; Humans; Male; Melanoma; Mic | 1997 |
Potentiation by phenylbisbenzimidazoles of cytotoxicity of anticancer drugs directed against topoisomerase II.
Topics: Acridines; Amsacrine; Animals; Antineoplastic Agents; Benzimidazoles; Bisbenzimidazole; Colonic Neop | 1990 |
Transplantation of B16/C3 melanoma cells into the brains of rats and mice.
Topics: Animals; Bisbenzimidazole; Brain; Catecholamines; Cell Line; DNA, Neoplasm; Fluorescent Dyes; Melano | 1989 |