bisbenzimidazole has been researched along with Leukemia L 1210 in 4 studies
Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gravatt, GL | 1 |
| Baguley, BC | 2 |
| Wilson, WR | 1 |
| Denny, WA | 1 |
| McHugh, MM | 1 |
| Sigmund, RD | 2 |
| Beerman, TA | 2 |
| Finlay, GJ | 1 |
| Woynarowski, JM | 1 |
4 other studies available for bisbenzimidazole and Leukemia L 1210
| Article | Year |
|---|---|
DNA-directed alkylating agents. 6. Synthesis and antitumor activity of DNA minor groove-targeted aniline mustard analogues of pibenzimol (Hoechst 33258)
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Binding Sites; Bisbenzimidazole; Cell Survival; C | 1994 |
Effects of minor groove binding drugs on camptothecin-induced DNA lesions in L1210 nuclei.
Topics: Animals; Benzimidazoles; Bisbenzimidazole; Camptothecin; Cell Nucleus; Distamycins; DNA Damage; DNA | 1990 |
Potentiation by phenylbisbenzimidazoles of cytotoxicity of anticancer drugs directed against topoisomerase II.
Topics: Acridines; Amsacrine; Animals; Antineoplastic Agents; Benzimidazoles; Bisbenzimidazole; Colonic Neop | 1990 |
DNA minor groove binding agents interfere with topoisomerase II mediated lesions induced by epipodophyllotoxin derivative VM-26 and acridine derivative m-AMSA in nuclei from L1210 cells.
Topics: Amsacrine; Animals; Bisbenzimidazole; Cell Nucleus; Deoxyribonucleoproteins; Distamycins; DNA Damage | 1989 |