bisbenzimidazole has been researched along with Colonic Neoplasms in 5 studies
Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The sigma receptor ligand reduced haloperidol (50 and 100 microM), potently inhibited cell proliferation, and induced apoptosis in WIDr colon and MCF-7 adenocarcinoma cell lines." | 7.69 | The sigma receptor ligand, reduced haloperidol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adenocarcinoma cells. ( Brent, PJ; Dosen, PJ; Little, G; Pang, G; Van Helden, DF, 1996) |
| "The sigma receptor ligand reduced haloperidol (50 and 100 microM), potently inhibited cell proliferation, and induced apoptosis in WIDr colon and MCF-7 adenocarcinoma cell lines." | 3.69 | The sigma receptor ligand, reduced haloperidol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adenocarcinoma cells. ( Brent, PJ; Dosen, PJ; Little, G; Pang, G; Van Helden, DF, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saiko, P | 1 |
| Bauer, W | 1 |
| Horvath, Z | 1 |
| Hoechtl, T | 1 |
| Grusch, M | 1 |
| Illmer, C | 1 |
| Madlener, S | 1 |
| Krupitza, G | 1 |
| Mader, RM | 1 |
| Schott, H | 1 |
| Fritzer-Szekeres, M | 1 |
| Szekeres, T | 1 |
| Noguchi, PD | 1 |
| Johnson, JB | 1 |
| Browne, W | 1 |
| Brent, PJ | 1 |
| Pang, G | 1 |
| Little, G | 1 |
| Dosen, PJ | 1 |
| Van Helden, DF | 1 |
| Leng, SL | 1 |
| Leeding, KS | 1 |
| Gibson, PR | 1 |
| Bach, LA | 1 |
| Finlay, GJ | 1 |
| Baguley, BC | 1 |
5 other studies available for bisbenzimidazole and Colonic Neoplasms
| Article | Year |
|---|---|
Cytotoxic and apoptotic effects of novel heterodinucleoside phosphates consisting of 5-fluorodeoxyuridine and Ara-C in human cancer cell lines.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Bisbenzimidazole; Cell Line, Tumor; Colonic Neoplasms; C | 2004 |
Measurement of DNA synthesis by flow cytometry.
Topics: Adenocarcinoma; Bisbenzimidazole; Bromodeoxyuridine; Cell Line; Colonic Neoplasms; DNA; Flow Cytomet | 1981 |
The sigma receptor ligand, reduced haloperidol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adenocarcinoma cells.
Topics: Adenocarcinoma; Apoptosis; Bisbenzimidazole; Breast Neoplasms; Calcium; Cell Line; Chromatin; Coloni | 1996 |
Insulin-like growth factor-II renders LIM 2405 human colon cancer cells resistant to butyrate-induced apoptosis: a potential mechanism for colon cancer cell survival in vivo.
Topics: Apoptosis; Bisbenzimidazole; Blotting, Western; Butyrates; Cell Movement; Cell Survival; Colonic Neo | 2001 |
Potentiation by phenylbisbenzimidazoles of cytotoxicity of anticancer drugs directed against topoisomerase II.
Topics: Acridines; Amsacrine; Animals; Antineoplastic Agents; Benzimidazoles; Bisbenzimidazole; Colonic Neop | 1990 |