bisbenzimidazole has been researched along with Carcinoma, Ehrlich Tumor in 6 studies
Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Carcinoma, Ehrlich Tumor: A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Single bolus dose and 28-days of repeated administration of DMA in mice for toxicity studies determined an LD50 of >2000 mg/kg body weight (bw) and 225 mg/kg bw, respectively, suggesting DMA is safe." | 1.42 | Preclinical Evaluation of DMA, a Bisbenzimidazole, as Radioprotector: Toxicity, Pharmacokinetics, and Biodistribution Studies in Balb/c Mice. ( Aneja, R; Chuttani, K; Gundala, SR; Hazari, PP; Katyal, A; Lal, J; Mishra, AK; Nimesh, H; Sharma, A; Tandon, V; Tiwari, V; Yang, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roopashree, R | 1 |
| Mohan, CD | 1 |
| Swaroop, TR | 1 |
| Jagadish, S | 1 |
| Raghava, B | 1 |
| Balaji, KS | 1 |
| Jayarama, S | 1 |
| Rangappa, KS | 1 |
| Nimesh, H | 1 |
| Tiwari, V | 1 |
| Yang, C | 1 |
| Gundala, SR | 1 |
| Chuttani, K | 1 |
| Hazari, PP | 1 |
| Mishra, AK | 1 |
| Sharma, A | 1 |
| Lal, J | 1 |
| Katyal, A | 1 |
| Aneja, R | 1 |
| Tandon, V | 1 |
| Zhao, X | 1 |
| Liu, Q | 1 |
| Tang, W | 1 |
| Wang, X | 1 |
| Wang, P | 1 |
| Gong, L | 1 |
| Wang, Y | 1 |
| Nüsse, M | 2 |
| Kroll, W | 1 |
6 other studies available for bisbenzimidazole and Carcinoma, Ehrlich Tumor
| Article | Year |
|---|---|
Novel synthetic bisbenzimidazole that targets angiogenesis in Ehrlich ascites carcinoma bearing mice.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Ascites; Bisbenzimidazole; Body Weight; Car | 2015 |
Preclinical Evaluation of DMA, a Bisbenzimidazole, as Radioprotector: Toxicity, Pharmacokinetics, and Biodistribution Studies in Balb/c Mice.
Topics: Animals; Benzimidazoles; Bisbenzimidazole; Carcinoma, Ehrlich Tumor; Dose-Response Relationship, Rad | 2015 |
Damage effects of protoporphyrin IX - sonodynamic therapy on the cytoskeletal F-actin of Ehrlich ascites carcinoma cells.
Topics: Actin Cytoskeleton; Actins; Animals; Bisbenzimidazole; Carcinoma, Ehrlich Tumor; Cell Death; Cell Li | 2009 |
Cell cycle kinetics of irradiated synchronous and asynchronous tumor cells with DNA distribution analysis and BrdUrd-Hoechst 33258-technique.
Topics: Animals; Bisbenzimidazole; Carcinoma, Ehrlich Tumor; Cell Cycle; DNA, Neoplasm; Flow Cytometry; Huma | 1981 |
Synchronization of mammalian cells by selection and additional chemical block studied by DNA distribution analysis and BrdUrd-Hoechst 33258-technique.
Topics: Animals; Bisbenzimidazole; Bromodeoxyuridine; Carcinoma, Ehrlich Tumor; Cell Separation; Cells, Cult | 1982 |
Modification of the BrdU/H33258 technique for flow cytometry based on the pH-dependence of the fluorescence of H33258 stained DNA.
Topics: Animals; Benzimidazoles; Bisbenzimidazole; Bromodeoxyuridine; Carcinoma, Ehrlich Tumor; DNA; DNA, Ne | 1984 |