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bisbenzimidazole and Breast Neoplasms

bisbenzimidazole has been researched along with Breast Neoplasms in 7 studies

Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"Tamoxifen has been reported to show an efficacy in the treatment of breast cancer."7.72Biochemical studies of apoptosis induced by tamoxifen in estrogen receptor positive and negative breast cancer cell lines. ( Karami-Tehrani, F; Salami, S, 2003)
"The sigma receptor ligand reduced haloperidol (50 and 100 microM), potently inhibited cell proliferation, and induced apoptosis in WIDr colon and MCF-7 adenocarcinoma cell lines."7.69The sigma receptor ligand, reduced haloperidol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adenocarcinoma cells. ( Brent, PJ; Dosen, PJ; Little, G; Pang, G; Van Helden, DF, 1996)
"Quercetin treatment resulted in the accumulation of cells specifically at G2/M phase of the cell cycle."5.31Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin. ( Choi, JA; Kang, CM; Kim, JY; Kim, TW; Kwon, HJ; Lee, JY; Lee, SJ; Lee, YS; Yoo, YD, 2001)
"Tamoxifen has been reported to show an efficacy in the treatment of breast cancer."3.72Biochemical studies of apoptosis induced by tamoxifen in estrogen receptor positive and negative breast cancer cell lines. ( Karami-Tehrani, F; Salami, S, 2003)
"The sigma receptor ligand reduced haloperidol (50 and 100 microM), potently inhibited cell proliferation, and induced apoptosis in WIDr colon and MCF-7 adenocarcinoma cell lines."3.69The sigma receptor ligand, reduced haloperidol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adenocarcinoma cells. ( Brent, PJ; Dosen, PJ; Little, G; Pang, G; Van Helden, DF, 1996)
"Quercetin treatment resulted in the accumulation of cells specifically at G2/M phase of the cell cycle."1.31Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin. ( Choi, JA; Kang, CM; Kim, JY; Kim, TW; Kwon, HJ; Lee, JY; Lee, SJ; Lee, YS; Yoo, YD, 2001)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barron, GA1
Bermano, G1
Gordon, A1
Kong Thoo Lin, P1
Zhou, Y1
Bi, Y1
Yang, C1
Yang, J1
Jiang, Y1
Meng, F1
Yu, B1
Khan, M1
Ma, T1
Yang, H1
Bielawski, K1
Bielawska, A1
Wołczyński, S1
Salami, S1
Karami-Tehrani, F1
Lockett, SJ1
Herman, B1
Brent, PJ1
Pang, G1
Little, G1
Dosen, PJ1
Van Helden, DF1
Choi, JA1
Kim, JY1
Lee, JY1
Kang, CM1
Kwon, HJ1
Yoo, YD1
Kim, TW1
Lee, YS1
Lee, SJ1

Other Studies

7 other studies available for bisbenzimidazole and Breast Neoplasms

ArticleYear
Synthesis, cytotoxicity and DNA-binding of novel bisnaphthalimidopropyl derivatives in breast cancer MDA-MB-231 cells.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Breast Neoplasms; Cell Line, Tumor; DNA, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans;

2010
Magnolol induces apoptosis in MCF-7 human breast cancer cells through G2/M phase arrest and caspase-independent pathway.
    Die Pharmazie, 2013, Volume: 68, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; Biphenyl Compounds; Bisbenz

2013
Synthesis, DNA-binding activity and cytotoxicity of carbamate derivatives of Hoechst 33258 in breast cancer MCF-7 cells.
    Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:7

    Topics: Animals; Antineoplastic Agents; Binding Sites; Bisbenzimidazole; Breast Neoplasms; Carbamates; Cattl

2002
Biochemical studies of apoptosis induced by tamoxifen in estrogen receptor positive and negative breast cancer cell lines.
    Clinical biochemistry, 2003, Volume: 36, Issue:4

    Topics: Annexin A5; Antineoplastic Agents, Hormonal; Apoptosis; bcl-2-Associated X Protein; Bisbenzimidazole

2003
Automatic detection of clustered, fluorescent-stained nuclei by digital image-based cytometry.
    Cytometry, 1994, Sep-01, Volume: 17, Issue:1

    Topics: Algorithms; Analog-Digital Conversion; Automation; Bisbenzimidazole; Breast Neoplasms; Cell Nucleus;

1994
The sigma receptor ligand, reduced haloperidol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adenocarcinoma cells.
    Biochemical and biophysical research communications, 1996, Feb-06, Volume: 219, Issue:1

    Topics: Adenocarcinoma; Apoptosis; Bisbenzimidazole; Breast Neoplasms; Calcium; Cell Line; Chromatin; Coloni

1996
Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin.
    International journal of oncology, 2001, Volume: 19, Issue:4

    Topics: Antisense Elements (Genetics); Apoptosis; Bisbenzimidazole; Breast Neoplasms; Cell Cycle; Cell Divis

2001