bisbenzimidazole has been researched along with Breast Neoplasms in 7 studies
Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tamoxifen has been reported to show an efficacy in the treatment of breast cancer." | 7.72 | Biochemical studies of apoptosis induced by tamoxifen in estrogen receptor positive and negative breast cancer cell lines. ( Karami-Tehrani, F; Salami, S, 2003) |
| "The sigma receptor ligand reduced haloperidol (50 and 100 microM), potently inhibited cell proliferation, and induced apoptosis in WIDr colon and MCF-7 adenocarcinoma cell lines." | 7.69 | The sigma receptor ligand, reduced haloperidol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adenocarcinoma cells. ( Brent, PJ; Dosen, PJ; Little, G; Pang, G; Van Helden, DF, 1996) |
| "Quercetin treatment resulted in the accumulation of cells specifically at G2/M phase of the cell cycle." | 5.31 | Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin. ( Choi, JA; Kang, CM; Kim, JY; Kim, TW; Kwon, HJ; Lee, JY; Lee, SJ; Lee, YS; Yoo, YD, 2001) |
| "Tamoxifen has been reported to show an efficacy in the treatment of breast cancer." | 3.72 | Biochemical studies of apoptosis induced by tamoxifen in estrogen receptor positive and negative breast cancer cell lines. ( Karami-Tehrani, F; Salami, S, 2003) |
| "The sigma receptor ligand reduced haloperidol (50 and 100 microM), potently inhibited cell proliferation, and induced apoptosis in WIDr colon and MCF-7 adenocarcinoma cell lines." | 3.69 | The sigma receptor ligand, reduced haloperidol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adenocarcinoma cells. ( Brent, PJ; Dosen, PJ; Little, G; Pang, G; Van Helden, DF, 1996) |
| "Quercetin treatment resulted in the accumulation of cells specifically at G2/M phase of the cell cycle." | 1.31 | Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin. ( Choi, JA; Kang, CM; Kim, JY; Kim, TW; Kwon, HJ; Lee, JY; Lee, SJ; Lee, YS; Yoo, YD, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barron, GA | 1 |
| Bermano, G | 1 |
| Gordon, A | 1 |
| Kong Thoo Lin, P | 1 |
| Zhou, Y | 1 |
| Bi, Y | 1 |
| Yang, C | 1 |
| Yang, J | 1 |
| Jiang, Y | 1 |
| Meng, F | 1 |
| Yu, B | 1 |
| Khan, M | 1 |
| Ma, T | 1 |
| Yang, H | 1 |
| Bielawski, K | 1 |
| Bielawska, A | 1 |
| Wołczyński, S | 1 |
| Salami, S | 1 |
| Karami-Tehrani, F | 1 |
| Lockett, SJ | 1 |
| Herman, B | 1 |
| Brent, PJ | 1 |
| Pang, G | 1 |
| Little, G | 1 |
| Dosen, PJ | 1 |
| Van Helden, DF | 1 |
| Choi, JA | 1 |
| Kim, JY | 1 |
| Lee, JY | 1 |
| Kang, CM | 1 |
| Kwon, HJ | 1 |
| Yoo, YD | 1 |
| Kim, TW | 1 |
| Lee, YS | 1 |
| Lee, SJ | 1 |
7 other studies available for bisbenzimidazole and Breast Neoplasms
| Article | Year |
|---|---|
Synthesis, cytotoxicity and DNA-binding of novel bisnaphthalimidopropyl derivatives in breast cancer MDA-MB-231 cells.
Topics: Breast Neoplasms; Cell Line, Tumor; DNA, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; | 2010 |
Magnolol induces apoptosis in MCF-7 human breast cancer cells through G2/M phase arrest and caspase-independent pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; Biphenyl Compounds; Bisbenz | 2013 |
Synthesis, DNA-binding activity and cytotoxicity of carbamate derivatives of Hoechst 33258 in breast cancer MCF-7 cells.
Topics: Animals; Antineoplastic Agents; Binding Sites; Bisbenzimidazole; Breast Neoplasms; Carbamates; Cattl | 2002 |
Biochemical studies of apoptosis induced by tamoxifen in estrogen receptor positive and negative breast cancer cell lines.
Topics: Annexin A5; Antineoplastic Agents, Hormonal; Apoptosis; bcl-2-Associated X Protein; Bisbenzimidazole | 2003 |
Automatic detection of clustered, fluorescent-stained nuclei by digital image-based cytometry.
Topics: Algorithms; Analog-Digital Conversion; Automation; Bisbenzimidazole; Breast Neoplasms; Cell Nucleus; | 1994 |
The sigma receptor ligand, reduced haloperidol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adenocarcinoma cells.
Topics: Adenocarcinoma; Apoptosis; Bisbenzimidazole; Breast Neoplasms; Calcium; Cell Line; Chromatin; Coloni | 1996 |
Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin.
Topics: Antisense Elements (Genetics); Apoptosis; Bisbenzimidazole; Breast Neoplasms; Cell Cycle; Cell Divis | 2001 |