bisbenzimidazole has been researched along with Alzheimer Disease in 1 studies
Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bursztajn, S | 1 |
| DeSouza, R | 1 |
| McPhie, DL | 1 |
| Berman, SA | 1 |
| Shioi, J | 1 |
| Robakis, NK | 1 |
| Neve, RL | 1 |
1 other study available for bisbenzimidazole and Alzheimer Disease
| Article | Year |
|---|---|
Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Apoptosis; Bisbenzimidazole; Cell Survival; Cereb | 1998 |