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bisbenzimidazole and Adenocarcinoma

bisbenzimidazole has been researched along with Adenocarcinoma in 4 studies

Bisbenzimidazole: A benzimidazole antifilarial agent; it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication; it also interferes with mitosis.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"The sigma receptor ligand reduced haloperidol (50 and 100 microM), potently inhibited cell proliferation, and induced apoptosis in WIDr colon and MCF-7 adenocarcinoma cell lines."7.69The sigma receptor ligand, reduced haloperidol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adenocarcinoma cells. ( Brent, PJ; Dosen, PJ; Little, G; Pang, G; Van Helden, DF, 1996)
"The sigma receptor ligand reduced haloperidol (50 and 100 microM), potently inhibited cell proliferation, and induced apoptosis in WIDr colon and MCF-7 adenocarcinoma cell lines."3.69The sigma receptor ligand, reduced haloperidol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adenocarcinoma cells. ( Brent, PJ; Dosen, PJ; Little, G; Pang, G; Van Helden, DF, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Noguchi, PD1
Johnson, JB1
Browne, W1
Brent, PJ1
Pang, G1
Little, G1
Dosen, PJ1
Van Helden, DF1
Nielsén, K1
Marcus, M1
Gropp, A1
Kraut, EH1
Fleming, T1
Segal, M1
Neidhart, JA1
Behrens, BC1
MacDonald, J1

Trials

1 trial available for bisbenzimidazole and Adenocarcinoma

ArticleYear
Phase II study of pibenzimol in pancreatic cancer. A Southwest Oncology Group study.
    Investigational new drugs, 1991, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Bisbenzimidazole; Drug Evaluation; Humans; Middle Aged; Pancreatic Neop

1991

Other Studies

3 other studies available for bisbenzimidazole and Adenocarcinoma

ArticleYear
Measurement of DNA synthesis by flow cytometry.
    Cytometry, 1981, Volume: 1, Issue:6

    Topics: Adenocarcinoma; Bisbenzimidazole; Bromodeoxyuridine; Cell Line; Colonic Neoplasms; DNA; Flow Cytomet

1981
The sigma receptor ligand, reduced haloperidol, induces apoptosis and increases intracellular-free calcium levels [Ca2+]i in colon and mammary adenocarcinoma cells.
    Biochemical and biophysical research communications, 1996, Feb-06, Volume: 219, Issue:1

    Topics: Adenocarcinoma; Apoptosis; Bisbenzimidazole; Breast Neoplasms; Calcium; Cell Line; Chromatin; Coloni

1996
Localization of NORs in chromosomes of mouse cell lines by a combined 33258-Hoechst and Ag-staining technique.
    Hereditas, 1979, Volume: 90, Issue:1

    Topics: Adenocarcinoma; Animals; Benzimidazoles; Bisbenzimidazole; Cell Line; Cell Nucleolus; Chromosomes; H

1979