Page last updated: 2024-10-23

bisacodyl and Ileus

bisacodyl has been researched along with Ileus in 4 studies

Bisacodyl: A diphenylmethane stimulant laxative used for the treatment of CONSTIPATION and for bowel evacuation. (From Martindale, The Extra Pharmacopoeia, 30th ed, p871)

Ileus: A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced.

Research Excerpts

ExcerptRelevanceReference
"To compare the use of bisacodyl suppository with placebo in resolving postoperative ileus after elective colectomy in a randomized controlled trial."9.12Randomized controlled trial of bisacodyl suppository versus placebo for postoperative ileus after elective colectomy for colon cancer. ( Euanorasetr, C; Kongdan, Y; Lertsithichai, P; Wacharachaisurapol, N; Wiriyakosol, S, 2007)
"To compare the use of bisacodyl suppository with placebo in resolving postoperative ileus after elective colectomy in a randomized controlled trial."5.12Randomized controlled trial of bisacodyl suppository versus placebo for postoperative ileus after elective colectomy for colon cancer. ( Euanorasetr, C; Kongdan, Y; Lertsithichai, P; Wacharachaisurapol, N; Wiriyakosol, S, 2007)
"Postoperative ileus is a common condition after abdominal surgery."2.73Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial. ( Hamel, CT; Metzger, U; Meyer, P; Miskovic, D; Pasternak, I; Zingg, U, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Dudi-Venkata, NN1
Kroon, HM1
Bedrikovetski, S1
Moore, JW1
Sammour, T1
Zingg, U1
Miskovic, D1
Pasternak, I1
Meyer, P1
Hamel, CT1
Metzger, U1
Zeinali, F1
Stulberg, JJ1
Delaney, CP1
Wiriyakosol, S1
Kongdan, Y1
Euanorasetr, C1
Wacharachaisurapol, N1
Lertsithichai, P1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Randomized Control Trial of The Effectiveness of Entereg as a Rescue Treatment of Postoperative Ileus Following Colorectal Surgery[NCT02742181]Phase 314 participants (Actual)Interventional2015-12-02Terminated (stopped due to terminated due to lack of enrollment)
A Prospective Randomized Control Trial of The Effectiveness of Alvimopan as a Rescue Treatment of Postoperative Ileus Following Colorectal Surgery[NCT04405037]Phase 458 participants (Anticipated)Interventional2020-08-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Complications

All adverse events (NCT02742181)
Timeframe: 30 days

InterventionNumber of AEs (Number)
Alvimopan Group4
Control Group6

Hospital Length of Stay

Date of surgery until discharge (NCT02742181)
Timeframe: up to 30 days

InterventionDays (Median)
Alvimopan Group9
Control Group8.5

Number of Readmissions

Any readmissions within 30 days of surgery (NCT02742181)
Timeframe: 30 days

InterventionNumber of readmissions (Number)
Alvimopan Group0
Control Group0

Number of Reoperations

Any reoperations within 30 days of surgery (NCT02742181)
Timeframe: 30 days

InterventionNumber of reoperations (Number)
Alvimopan Group0
Control Group0

Reviews

2 reviews available for bisacodyl and Ileus

ArticleYear
Systematic scoping review of enhanced recovery protocol recommendations targeting return of gastrointestinal function after colorectal surgery.
    ANZ journal of surgery, 2020, Volume: 90, Issue:1-2

    Topics: Bisacodyl; Chewing Gum; Colonic Diseases; Humans; Ileus; Lactulose; Neostigmine; Piperidines; Postop

2020
Pharmacological management of postoperative ileus.
    Canadian journal of surgery. Journal canadien de chirurgie, 2009, Volume: 52, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal;

2009

Trials

2 trials available for bisacodyl and Ileus

ArticleYear
Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial.
    International journal of colorectal disease, 2008, Volume: 23, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bisacodyl; Cathartics; Colon; Double-Blind Method; Elect

2008
Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial.
    International journal of colorectal disease, 2008, Volume: 23, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bisacodyl; Cathartics; Colon; Double-Blind Method; Elect

2008
Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial.
    International journal of colorectal disease, 2008, Volume: 23, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bisacodyl; Cathartics; Colon; Double-Blind Method; Elect

2008
Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial.
    International journal of colorectal disease, 2008, Volume: 23, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bisacodyl; Cathartics; Colon; Double-Blind Method; Elect

2008
Randomized controlled trial of bisacodyl suppository versus placebo for postoperative ileus after elective colectomy for colon cancer.
    Asian journal of surgery, 2007, Volume: 30, Issue:3

    Topics: Adult; Aged; Bisacodyl; Cathartics; Colectomy; Colonic Neoplasms; Female; Humans; Ileus; Male; Middl

2007