bisacodyl and Ileus
bisacodyl has been researched along with Ileus in 4 studies
Bisacodyl: A diphenylmethane stimulant laxative used for the treatment of CONSTIPATION and for bowel evacuation. (From Martindale, The Extra Pharmacopoeia, 30th ed, p871)
Ileus: A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the use of bisacodyl suppository with placebo in resolving postoperative ileus after elective colectomy in a randomized controlled trial." | 9.12 | Randomized controlled trial of bisacodyl suppository versus placebo for postoperative ileus after elective colectomy for colon cancer. ( Euanorasetr, C; Kongdan, Y; Lertsithichai, P; Wacharachaisurapol, N; Wiriyakosol, S, 2007) |
| "To compare the use of bisacodyl suppository with placebo in resolving postoperative ileus after elective colectomy in a randomized controlled trial." | 5.12 | Randomized controlled trial of bisacodyl suppository versus placebo for postoperative ileus after elective colectomy for colon cancer. ( Euanorasetr, C; Kongdan, Y; Lertsithichai, P; Wacharachaisurapol, N; Wiriyakosol, S, 2007) |
| "Postoperative ileus is a common condition after abdominal surgery." | 2.73 | Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial. ( Hamel, CT; Metzger, U; Meyer, P; Miskovic, D; Pasternak, I; Zingg, U, 2008) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Dudi-Venkata, NN | 1 |
| Kroon, HM | 1 |
| Bedrikovetski, S | 1 |
| Moore, JW | 1 |
| Sammour, T | 1 |
| Zingg, U | 1 |
| Miskovic, D | 1 |
| Pasternak, I | 1 |
| Meyer, P | 1 |
| Hamel, CT | 1 |
| Metzger, U | 1 |
| Zeinali, F | 1 |
| Stulberg, JJ | 1 |
| Delaney, CP | 1 |
| Wiriyakosol, S | 1 |
| Kongdan, Y | 1 |
| Euanorasetr, C | 1 |
| Wacharachaisurapol, N | 1 |
| Lertsithichai, P | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Randomized Control Trial of The Effectiveness of Entereg as a Rescue Treatment of Postoperative Ileus Following Colorectal Surgery[NCT02742181] | Phase 3 | 14 participants (Actual) | Interventional | 2015-12-02 | Terminated (stopped due to terminated due to lack of enrollment) | ||
| A Prospective Randomized Control Trial of The Effectiveness of Alvimopan as a Rescue Treatment of Postoperative Ileus Following Colorectal Surgery[NCT04405037] | Phase 4 | 58 participants (Anticipated) | Interventional | 2020-08-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trial Outcomes
Complications
All adverse events (NCT02742181)
Timeframe: 30 days
| Intervention | Number of AEs (Number) |
|---|---|
| Alvimopan Group | 4 |
| Control Group | 6 |
Hospital Length of Stay
Date of surgery until discharge (NCT02742181)
Timeframe: up to 30 days
| Intervention | Days (Median) |
|---|---|
| Alvimopan Group | 9 |
| Control Group | 8.5 |
Number of Readmissions
Any readmissions within 30 days of surgery (NCT02742181)
Timeframe: 30 days
| Intervention | Number of readmissions (Number) |
|---|---|
| Alvimopan Group | 0 |
| Control Group | 0 |
Number of Reoperations
Any reoperations within 30 days of surgery (NCT02742181)
Timeframe: 30 days
| Intervention | Number of reoperations (Number) |
|---|---|
| Alvimopan Group | 0 |
| Control Group | 0 |
Reviews
2 reviews available for bisacodyl and Ileus
| Article | Year |
|---|---|
Systematic scoping review of enhanced recovery protocol recommendations targeting return of gastrointestinal function after colorectal surgery.
Topics: Bisacodyl; Chewing Gum; Colonic Diseases; Humans; Ileus; Lactulose; Neostigmine; Piperidines; Postop | 2020 |
Pharmacological management of postoperative ileus.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; | 2009 |
Trials
2 trials available for bisacodyl and Ileus
| Article | Year |
|---|---|
Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bisacodyl; Cathartics; Colon; Double-Blind Method; Elect | 2008 |
Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bisacodyl; Cathartics; Colon; Double-Blind Method; Elect | 2008 |
Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bisacodyl; Cathartics; Colon; Double-Blind Method; Elect | 2008 |
Effect of bisacodyl on postoperative bowel motility in elective colorectal surgery: a prospective, randomized trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bisacodyl; Cathartics; Colon; Double-Blind Method; Elect | 2008 |
Randomized controlled trial of bisacodyl suppository versus placebo for postoperative ileus after elective colectomy for colon cancer.
Topics: Adult; Aged; Bisacodyl; Cathartics; Colectomy; Colonic Neoplasms; Female; Humans; Ileus; Male; Middl | 2007 |