bisacodyl has been researched along with Electrolytes in 29 studies
Bisacodyl: A diphenylmethane stimulant laxative used for the treatment of CONSTIPATION and for bowel evacuation. (From Martindale, The Extra Pharmacopoeia, 30th ed, p871)
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the bowel-cleansing efficacy and patient tolerability of split-dose 2 L PEG3350 + electrolytes (PEG3350e) with 15 mg bisacodyl versus split-dose 4 L PEG3350e." | 5.19 | 2 L versus 4 L of PEG3350 + electrolytes for outpatient colonic preparation: a randomized, controlled trial. ( Brahmania, M; Bressler, B; Enns, R; Ko, HK; Lam, E; Ou, G; Telford, J, 2014) |
| " It was investigated in rats whether chronic administration of bisacodyl reduces the effects of acute bisacodyl administration on net water and electrolyte flux in the rat colon transport in-vivo." | 1.27 | Influence of chronic bisacodyl treatment on the effect of acute bisacodyl on water and electrolyte transport in the rat colon. ( Beubler, E, 1985) |
| " Deacetylbisacodyl was more potent than the parent compound and was used to investigate dose-response relationships." | 1.27 | The influence of bisacodyl and deacetylbisacodyl on mucus secretion, mucus synthesis and electrolyte movements in the rat colon in vivo. ( Farack, UM; Gruber, E; Loeschke, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (37.93) | 18.7374 |
| 1990's | 8 (27.59) | 18.2507 |
| 2000's | 4 (13.79) | 29.6817 |
| 2010's | 6 (20.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, MA | 1 |
| Patel, KB | 1 |
| Nooruddin, M | 1 |
| Swanson, G | 1 |
| Fogg, L | 1 |
| Keshavarzian, A | 1 |
| Brown, M | 1 |
| Sey, MSL | 1 |
| von Renteln, D | 1 |
| Sultanian, R | 1 |
| McDonald, C | 1 |
| Martel, M | 1 |
| Barkun, A | 1 |
| Brahmania, M | 1 |
| Ou, G | 1 |
| Bressler, B | 1 |
| Ko, HK | 1 |
| Lam, E | 1 |
| Telford, J | 1 |
| Enns, R | 1 |
| Rex, DK | 1 |
| McGowan, J | 1 |
| Cleveland, Mv | 1 |
| Di Palma, JA | 1 |
| Fujita, T | 1 |
| Karaki, S | 1 |
| Tateoka, T | 1 |
| Kuwahara, A | 1 |
| Turner, D | 1 |
| Levine, A | 1 |
| Weiss, B | 1 |
| Hirsh, A | 1 |
| Shamir, R | 1 |
| Shaoul, R | 1 |
| Berkowitz, D | 1 |
| Bujanover, Y | 1 |
| Cohen, S | 1 |
| Eshach-Adiv, O | 1 |
| Jamal, G | 1 |
| Kori, M | 1 |
| Lerner, A | 1 |
| On, A | 1 |
| Rachman, L | 1 |
| Rosenbach, Y | 1 |
| Shamaly, H | 1 |
| Shteyer, E | 1 |
| Silbermintz, A | 1 |
| Yerushalmi, B | 1 |
| Wexner, SD | 1 |
| Beck, DE | 1 |
| Baron, TH | 1 |
| Fanelli, RD | 1 |
| Hyman, N | 1 |
| Shen, B | 1 |
| Wasco, KE | 1 |
| Juchems, MS | 1 |
| Hoffmann, MH | 1 |
| Schmidt, SA | 1 |
| Apostel, A | 1 |
| Brambs, HJ | 1 |
| Aschoff, AJ | 1 |
| Ker, TS | 1 |
| Edmonds, CJ | 1 |
| Karbach, U | 1 |
| Wanitschke, R | 1 |
| Girard, CM | 1 |
| Rugh, KS | 1 |
| DiPalma, JA | 3 |
| Brady, CE | 3 |
| Pierson, WP | 2 |
| Gaginella, TS | 1 |
| Mascolo, N | 1 |
| Izzo, AA | 1 |
| Autore, G | 1 |
| Capasso, F | 1 |
| Afridi, SA | 1 |
| Barthel, JS | 1 |
| King, PD | 1 |
| Pineda, JJ | 1 |
| Marshall, JB | 1 |
| Rosman, AS | 1 |
| Federman, Q | 1 |
| Feinman, L | 1 |
| Clarkston, WK | 1 |
| Smith, OJ | 1 |
| Kishibayashi, N | 1 |
| Karasawa, A | 1 |
| Dahshan, A | 1 |
| Lin, CH | 1 |
| Peters, J | 1 |
| Thomas, R | 1 |
| Tolia, V | 1 |
| Macari, M | 1 |
| Lavelle, M | 1 |
| Pedrosa, I | 1 |
| Milano, A | 1 |
| Dicker, M | 1 |
| Megibow, AJ | 1 |
| Xue, X | 1 |
| Donowitz, M | 1 |
| Ziegenhagen, DJ | 1 |
| Zehnter, E | 1 |
| Tacke, W | 1 |
| Gheorghiu, T | 1 |
| Kruis, W | 1 |
| Lashner, BA | 1 |
| Winans, CS | 1 |
| Blackstone, MO | 1 |
| Leng-Peschlow, E | 1 |
| Rings, EH | 1 |
| Mulder, CJ | 1 |
| Tytgat, GN | 1 |
| Beubler, E | 1 |
| Ewe, K | 1 |
| Farack, UM | 1 |
| Gruber, E | 1 |
| Loeschke, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-centre Endoscopist Blinded Randomized Clinical Trial to Compare Two Bowel Preparations After a Colonoscopy With Inadequate Bowel Preparation[NCT02976805] | Phase 3 | 196 participants (Actual) | Interventional | 2017-02-13 | Completed | ||
| The Bowel CLEAnsing: A National Initiative[NCT02547571] | Phase 4 | 3,476 participants (Actual) | Interventional | 2016-03-31 | Completed | ||
| Sodium Sulfate/Potassium Sulfate/Magnesium Sulfate Bowel Preparation With and Without Simethicone for Routine Colonoscopy: A Double-blinded Randomized Controlled Trial[NCT02523911] | 0 participants (Actual) | Interventional | 2016-03-31 | Withdrawn (stopped due to investigator graduated and is not longer at this institution) | |||
| A Comparison of Restrictive and Liberal Fluid Administration During Elective Colonoscopy Under Sedoanalgesia[NCT05522127] | 100 participants (Anticipated) | Interventional | 2022-10-11 | Recruiting | |||
| Lubiprostone Plus Polyethylene Glycol-electrolyte Solutionvs. Placebo Plus Polyethylene Glycol-electrolyte Solution for Outpatient Colonoscopy Preparation: A Randomized, Double-blind, Placebo-controlled Trial[NCT00645801] | Phase 4 | 158 participants (Actual) | Interventional | 2008-03-31 | Completed | ||
| Randomized Controlled Trial Comparing Split-versus Standard-dose Sodium Pico Sulfate Plus Magnesium Citrate for Bowel Cleansing Before Colonoscopy in Children[NCT04767633] | Phase 3 | 590 participants (Anticipated) | Interventional | 2021-04-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patients in the lubiprostone group and the placebo returned unused PEG after completing the prep for the colonoscopy. This was measured in liters and recorded. (NCT00645801)
Timeframe: amount of PEG at start of the study and that measured when the patient presented for their procedure.
| Intervention | liters (Mean) |
|---|---|
| Ingested 4 Tablets of Placebo in Divided Doses + 1 Gallon of Polyethylene Glycol | 0.79 |
| Ingested 4 Tablets of Lubiprostone in Divided Doses + 1 Gallon of Polyethylene Glycol | 1.36 |
Endoscopists evaluated the quality of the colonoscopy preparation based on Ottawa bowel preparation scale. . The total score ranges from 0-14; score of 0 being perfect and score of 14 indicating solid stool in each colon segment and lot of fluid. Before using the scale for this trial, the endoscopists participated in a calibration exercise that involved 20 patients to ensure that they concurred on their interpretation of the scale. (NCT00645801)
Timeframe: within 12 hours of completing bowel prep
| Intervention | score on a scale (Mean) |
|---|---|
| Look Alike Placebo in 4 Divided Doses Plus PEG and Electrolytes. | 1.38 |
| Patient Received Both Lubiprostone in 4 Divided Doses and Golytely. | 1.24 |
After completing the colonoscopy prep patients were asked to assess tolerability of the prep using a 5 point Likert scale with 1 being easy and 5 being unable to complete the prep (NCT00645801)
Timeframe: done at the time of colonoscopy
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| easy | Tolerable | slightly difficult | extremely difficult | unable to finish | |
| Ingested 4 Tablets of Lubiprostone in Divided Doses + 1 Gallon of Polyethylene Glycol | 6 | 15 | 18 | 6 | 7 |
| Ingested 4 Tablets of Placebo in Divided Doses + 1 Gallon of Polyethylene Glycol | 4 | 14 | 25 | 15 | 6 |
2 reviews available for bisacodyl and Electrolytes
| Article | Year |
|---|---|
Evidence-based recommendations for bowel cleansing before colonoscopy in children: a report from a national working group.
Topics: Bisacodyl; Cathartics; Child; Child, Preschool; Citrates; Colonoscopy; Diet; Electrolytes; Enema; Ev | 2010 |
Absorption and secretion of fluid and electrolytes by the rectum.
Topics: Animals; Bicarbonates; Bisacodyl; Chlorine; Colitis; Electrolytes; Fludrocortisone; Humans; Intestin | 1984 |
12 trials available for bisacodyl and Electrolytes
| Article | Year |
|---|---|
Polyethylene Glycol-3350 (Miralax®)+1.9-L sports drink (Gatorade®)+2 tablets of bisacodyl results in inferior bowel preparation for colonoscopy compared with Polyethylene Glycol-Ascorbic Acid (MoviPrep®).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ascorbic Acid; Bisacodyl; Cathartics; Colon; Colonoscopy | 2018 |
Multicentre endoscopist-blinded randomised clinical trial to compare two bowel preparations after a colonoscopy with inadequate cleansing: a study protocol.
Topics: Bisacodyl; Canada; Cathartics; Clinical Trials, Phase III as Topic; Colonoscopy; Colorectal Neoplasm | 2019 |
2 L versus 4 L of PEG3350 + electrolytes for outpatient colonic preparation: a randomized, controlled trial.
Topics: Adult; Aged, 80 and over; Bisacodyl; Cathartics; Colonoscopy; Electrolytes; Female; Humans; Male; Mi | 2014 |
A randomized, controlled trial of oral sulfate solution plus polyethylene glycol as a bowel preparation for colonoscopy.
Topics: Aged; Ascorbic Acid; Bisacodyl; Cathartics; Colonoscopy; Electrolytes; Female; Humans; Magnesium Sul | 2014 |
Comparison of reduced volume versus four-liter electrolyte lavage solutions for colon cleansing.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Bisacodyl; Cathartics; Colon; Colonoscop | 2006 |
Comparison of Golytely lavage with standard diet/cathartic preparation for double-contrast barium enema.
Topics: Adult; Barium Sulfate; Bisacodyl; Cathartics; Diet; Electrolytes; Enema; Female; Humans; Male; Middl | 1984 |
Prospective, randomized trial comparing a new sodium phosphate-bisacodyl regimen with conventional PEG-ES lavage for outpatient colonoscopy preparation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bisacodyl; Colonoscopy; Cost-Benefit Analysis; Drug Admi | 1995 |
The use of GoLYTELY and Dulcolax in combination in outpatient colonoscopy.
Topics: Ambulatory Care; Bisacodyl; Colonoscopy; Double-Blind Method; Electrolytes; Female; Humans; Male; Mi | 1993 |
A randomized, prospective study to evaluate the efficacy and acceptance of three bowel preparations for colonoscopy in children.
Topics: Adolescent; Adult; Anthraquinones; Bisacodyl; Cathartics; Child; Child, Preschool; Citric Acid; Colo | 1999 |
Senna vs. bisacodyl in addition to Golytely lavage for colonoscopy preparation--a prospective randomized trial.
Topics: Adult; Aged; Bisacodyl; Cathartics; Colonoscopy; Electrolytes; Female; Humans; Male; Middle Aged; Po | 1992 |
Randomized clinical trial of two colonoscopy preparation methods for elderly patients.
Topics: Aged; Aged, 80 and over; Bisacodyl; Citrates; Citric Acid; Colonoscopy; Electrolytes; Enema; Female; | 1990 |
Colon cleansing: acceptance by older patients.
Topics: Age Factors; Anthraquinones; Barium Sulfate; Bisacodyl; Cathartics; Citrates; Citric Acid; Colon; Co | 1986 |
15 other studies available for bisacodyl and Electrolytes
| Article | Year |
|---|---|
Desacetyl bisacodyl-induced epithelial Cl(-) secretion in rat colon and rectum.
Topics: Action Potentials; Animals; Bisacodyl; Chlorides; Colon; Electrolytes; Electrophysiological Phenomen | 2016 |
A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal
Topics: Bisacodyl; Cathartics; Colonoscopy; Diet; Electrolytes; Enema; Flavoring Agents; Humans; Polyethylen | 2006 |
A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal
Topics: Bisacodyl; Cathartics; Colonoscopy; Diet; Electrolytes; Enema; Flavoring Agents; Humans; Polyethylen | 2006 |
A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal
Topics: Bisacodyl; Cathartics; Colonoscopy; Diet; Electrolytes; Enema; Flavoring Agents; Humans; Polyethylen | 2006 |
A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal
Topics: Bisacodyl; Cathartics; Colonoscopy; Diet; Electrolytes; Enema; Flavoring Agents; Humans; Polyethylen | 2006 |
A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal
Topics: Bisacodyl; Cathartics; Colonoscopy; Diet; Electrolytes; Enema; Flavoring Agents; Humans; Polyethylen | 2006 |
A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal
Topics: Bisacodyl; Cathartics; Colonoscopy; Diet; Electrolytes; Enema; Flavoring Agents; Humans; Polyethylen | 2006 |
A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal
Topics: Bisacodyl; Cathartics; Colonoscopy; Diet; Electrolytes; Enema; Flavoring Agents; Humans; Polyethylen | 2006 |
A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal
Topics: Bisacodyl; Cathartics; Colonoscopy; Diet; Electrolytes; Enema; Flavoring Agents; Humans; Polyethylen | 2006 |
A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal
Topics: Bisacodyl; Cathartics; Colonoscopy; Diet; Electrolytes; Enema; Flavoring Agents; Humans; Polyethylen | 2006 |
Bowel preparation for CT-colonography: comparison of two different cleansing protocols.
Topics: Bisacodyl; Cathartics; Colonography, Computed Tomographic; Electrolytes; Female; Humans; Male; Middl | 2006 |
Influence of serosal hydrostatic pressure on net water and electrolyte transport across the isolated rat colonic mucosa exposed to different secretagogues.
Topics: Animals; Anthraquinones; Bisacodyl; Body Water; Cell Membrane Permeability; Cholera Toxin; Colon; De | 1984 |
Nitric oxide as a mediator of bisacodyl and phenolphthalein laxative action: induction of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Bisacodyl; Body Water; Cathartics; Colon; Dexamethasone; Electr | 1994 |
Diagnosis of colon cancer by lavage cytology with an orally administered balanced electrolyte solution.
Topics: Administration, Oral; Aged; Bisacodyl; Colon; Colonoscopy; Colorectal Neoplasms; Confidence Interval | 1994 |
Effects of KW-5092, a novel gastroprokinetic agent, on intestinal water and electrolyte transport in rats.
Topics: Animals; Bisacodyl; Cathartics; Cholinesterase Inhibitors; Colon; Dose-Response Relationship, Drug; | 1995 |
Effect of different bowel preparations on residual fluid at CT colonography.
Topics: Aged; Bisacodyl; Cathartics; Colon; Electrolytes; Female; Humans; Male; Middle Aged; Phosphates; Pol | 2001 |
Current concepts of laxative action: mechanisms by which laxatives increase stool water.
Topics: Anthraquinones; Bile Acids and Salts; Bisacodyl; Body Water; Castor Oil; Cathartics; Citrates; Citri | 1979 |
Effects of sennosides A + B and bisacodyl on rat large intestine.
Topics: Administration, Oral; Animals; Anthraquinones; Bisacodyl; Body Water; Cathartics; Colon; Cresols; El | 1989 |
The effect of bisacodyl on whole-gut irrigation in preparation for colonoscopy.
Topics: Bisacodyl; Colonoscopy; Cresols; Electrolytes; Female; Humans; Male; Middle Aged; Premedication; Sol | 1989 |
Influence of chronic bisacodyl treatment on the effect of acute bisacodyl on water and electrolyte transport in the rat colon.
Topics: Aldosterone; Animals; Biological Transport; Bisacodyl; Body Water; Colon; Cresols; Electrolytes; Fem | 1985 |
Effect of bisacodyl on intestinal electrolyte and water net transport and transit. Perfusion studies in men.
Topics: Adult; Aged; Biological Transport, Active; Bisacodyl; Cresols; Electrolytes; Gastrointestinal Motili | 1987 |
A rapid colonic lavage solution (Golytely) vs standard preparation for barium enema and colonoscopy.
Topics: Administration, Oral; Barium Sulfate; Bisacodyl; Electrolytes; Enema; Humans; Polyethylene Glycols; | 1986 |
The influence of bisacodyl and deacetylbisacodyl on mucus secretion, mucus synthesis and electrolyte movements in the rat colon in vivo.
Topics: Animals; Bisacodyl; Colon; Cresols; Dose-Response Relationship, Drug; Electrolytes; Female; Intestin | 1985 |