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bis(4-nitrophenyl)phosphate and Chemical and Drug Induced Liver Injury

bis(4-nitrophenyl)phosphate has been researched along with Chemical and Drug Induced Liver Injury in 2 studies

bis(4-nitrophenyl)phosphate: RN given refers to parent cpd

Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.

Research Excerpts

ExcerptRelevanceReference
" Toxic doses of acetylisoniazid and acetylhydrazine, radiolabeled in the acetyl group, were found to bind covalently to liver protein in vivo."1.26Isoniazid hepatoxicity: the relationship between covalent binding and metabolism in vivo. ( Mitchell, JR; Nelson, SD; Snodgrass, WR; Timbrell, JA, 1980)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Timbrell, JA1
Mitchell, JR1
Snodgrass, WR1
Nelson, SD1
Sarich, TC1
Adams, SP1
Petricca, G1
Wright, JM1

Other Studies

2 other studies available for bis(4-nitrophenyl)phosphate and Chemical and Drug Induced Liver Injury

ArticleYear
Isoniazid hepatoxicity: the relationship between covalent binding and metabolism in vivo.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:2

    Topics: Acetylation; Amidohydrolases; Animals; Biotransformation; Carbon Dioxide; Chemical and Drug Induced

1980
Inhibition of isoniazid-induced hepatotoxicity in rabbits by pretreatment with an amidase inhibitor.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2

    Topics: Amidohydrolases; Animals; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cytochrome

1999