Page last updated: 2024-09-04

birb 796 and Disease Models, Animal

birb 796 has been researched along with Disease Models, Animal in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (22.22)	29.6817
2010's	3 (33.33)	24.3611
2020's	4 (44.44)	2.80

Authors

Authors	Studies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV	1
Alganem, K; Breidenbach, JD; Dube, P; French, BW; Haller, ST; Kennedy, DJ; Khalaf, FK; Malhotra, D; McCullumsmith, R; Presloid, JB; Su, RC; Wooten, RM	1
Calkins, DJ; Carlson, BJ; Collyer, JW; Formichella, CR; Ghose, P; Lambert, WS; Pasini, S	1
Appelmann, I; Brümmendorf, TH; Kharabi Masouleh, B; Patterson, JB; Preisinger, C; Salimi, A; Samali, A; Schemionek, M; Vieri, M	1
Brindley, C; Charron, CE; Ito, K; Kizawa, Y; Lea, S; Russell, P; Singh, D	1
Clasen, T; Fähling, M; Ishak, B; Kojda, G; Mende, S; Patzak, A; Potthoff, SA; Rump, LC; Sivritas, SH; Stamer, S; Stegbauer, J; Suvorava, T; Thieme, M	1
Chen, SC; Engstrom, L; Fine, JS; Kinsley, D; Li, Y; Manfra, D; Mihara, K; Nelissen, R; Pinzon-Ortiz, MC	1
Anur, P; Bagby, GC; Cappelli, E; Dufour, C; Garbati, MR; Hays, LE; Keeble, W; Rathbun, K; Svahn, J; Tyner, JW; Vanderwerf, S; Yates, J	1
Al-Saadi, N; Dechend, R; Feldt, S; Fiebeler, A; Fischer, R; Gapeljuk, A; Gratze, P; Haller, H; Luft, FC; Madwed, JB; Meiners, S; Muller, DN; Park, JK; Schirdewan, A; Shagdarsuren, E; Wellner, M	1

Trials

1 trial(s) available for birb 796 and Disease Models, Animal

Article	Year
RV568, a narrow-spectrum kinase inhibitor with p38 MAPK-α and -γ selectivity, suppresses COPD inflammation. The European respiratory journal, 2017, Volume: 50, Issue:4 Topics: Adrenal Cortex Hormones; Adult; Aged; Animals; Anti-Inflammatory Agents; Cigarette Smoking; Disease Models, Animal; Double-Blind Method; Epithelial Cells; Female; Forced Expiratory Volume; Humans; Macrophages; Male; Mice; Middle Aged; Monocytes; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Pyrazoles; Sputum; United Kingdom	2017

Article

Year

RV568, a narrow-spectrum kinase inhibitor with p38 MAPK-α and -γ selectivity, suppresses COPD inflammation.

The European respiratory journal, 2017, Volume: 50, Issue:4

Topics: Adrenal Cortex Hormones; Adult; Aged; Animals; Anti-Inflammatory Agents; Cigarette Smoking; Disease Models, Animal; Double-Blind Method; Epithelial Cells; Female; Forced Expiratory Volume; Humans; Macrophages; Male; Mice; Middle Aged; Monocytes; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Pyrazoles; Sputum; United Kingdom

2017

Other Studies

8 other study(ies) available for birb 796 and Disease Models, Animal

Article	Year
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49 Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection	2020
Microcystin-LR (MC-LR) Triggers Inflammatory Responses in Macrophages. International journal of molecular sciences, 2021, Sep-14, Volume: 22, Issue:18 Topics: Animals; Biomarkers; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation; Inflammation; Macrophages; Male; Marine Toxins; Mice, Inbred C57BL; Mice, Knockout; Microcystins; Naphthalenes; Protein Kinases; Proteome; Pyrazoles; Rats	2021
Of Mice and Monkeys: Neuroprotective Efficacy of the p38 Inhibitor BIRB 796 Depends on Model Duration in Experimental Glaucoma. Scientific reports, 2020, 05-22, Volume: 10, Issue:1 Topics: Animals; Axonal Transport; Disease Models, Animal; Glaucoma; Intraocular Pressure; Male; Mice; Mice, Inbred DBA; Naphthalenes; Neuroprotective Agents; Optic Nerve; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyrazoles; Rats; Retinal Ganglion Cells; Saimiri	2020
Targeting of BCR-ABL1 and IRE1α induces synthetic lethality in Philadelphia-positive acute lymphoblastic leukemia. Carcinogenesis, 2021, 02-25, Volume: 42, Issue:2 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Benzopyrans; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Synergism; Endoribonucleases; Fusion Proteins, bcr-abl; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice, Transgenic; Morpholines; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Cell Culture; Protein Serine-Threonine Kinases; Pyrazoles; Pyridines; Pyrimidines; Synthetic Lethal Mutations; X-Box Binding Protein 1	2021
Angiotensin-(1-7) modulates renal vascular resistance through inhibition of p38 mitogen-activated protein kinase in apolipoprotein E-deficient mice. Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:2 Topics: Angiotensin I; Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; Disease Models, Animal; Female; Hypertension, Renal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naphthalenes; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyrazoles; Receptors, G-Protein-Coupled; Renal Circulation; Vascular Resistance	2014
Characterization of a murine keyhole limpet hemocyanin (KLH)-delayed-type hypersensitivity (DTH) model: role for p38 kinase. International immunopharmacology, 2009, Volume: 9, Issue:10 Topics: Animals; Cytokines; Disease Models, Animal; Ear; Female; Hemocyanins; Hypersensitivity, Delayed; Immunization; Injections, Intradermal; Mice; Mice, Inbred BALB C; Naphthalenes; Neutrophil Infiltration; Organ Culture Techniques; Otitis; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyrazoles; Signal Transduction	2009
p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytes. Blood, 2012, Mar-01, Volume: 119, Issue:9 Topics: Animals; Cell Line; Dasatinib; Disease Models, Animal; Enzyme Activation; Fanconi Anemia; Fanconi Anemia Complementation Group A Protein; Fanconi Anemia Complementation Group C Protein; Gene Expression Regulation; Gene Knockout Techniques; Humans; Macrophages; Matrix Metalloproteinases; Mice; Mice, Knockout; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phagocytes; Phenotype; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Pyrazoles; Pyrimidines; RNA Processing, Post-Transcriptional; Small Molecule Libraries; src-Family Kinases; Thiazoles; Toll-Like Receptors; Transcription, Genetic; Tumor Necrosis Factor-alpha	2012
p38 mitogen-activated protein kinase inhibition ameliorates angiotensin II-induced target organ damage. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:3 Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Cardiovascular Diseases; Disease Models, Animal; Kidney Diseases; Male; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyrazoles; Rats; Rats, Sprague-Dawley; Renin	2007