Page last updated: 2024-10-23

biperiden and Psychotic Disorders

biperiden has been researched along with Psychotic Disorders in 21 studies

Biperiden: A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
biperiden : A member of the class of piperidines that is N-propylpiperidine in which the methyl hydrogens have been replaced by hydroxy, phenyl, and 5-norbornen-2-yl groups. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all forms of Parkinson's disease.

Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
" Efficacy of ziprasidone (80-160 mg/d) and olanzapine 10-20 mg was measured using the Positive and Negative Syndrome Scale (PANSS), the Clinical Global Impression (CGI) Scale, the Calgary Depression Scale for Schizophrenia (CDSS), and the Heinrich Quality of Life Scale (HQLS); tolerability assessments included laboratory assessments, body weight, and electroencephalogram."9.15Ziprasidone vs olanzapine in recent-onset schizophrenia and schizoaffective disorder: results of an 8-week double-blind randomized controlled trial. ( Buitelaar, JK; Grootens, KP; Kahn, RS; Peuskens, J; Sabbe, BG; Thys, E; van Veelen, NM; Verkes, RJ, 2011)
" Efficacy of ziprasidone (80-160 mg/d) and olanzapine 10-20 mg was measured using the Positive and Negative Syndrome Scale (PANSS), the Clinical Global Impression (CGI) Scale, the Calgary Depression Scale for Schizophrenia (CDSS), and the Heinrich Quality of Life Scale (HQLS); tolerability assessments included laboratory assessments, body weight, and electroencephalogram."5.15Ziprasidone vs olanzapine in recent-onset schizophrenia and schizoaffective disorder: results of an 8-week double-blind randomized controlled trial. ( Buitelaar, JK; Grootens, KP; Kahn, RS; Peuskens, J; Sabbe, BG; Thys, E; van Veelen, NM; Verkes, RJ, 2011)
"Sixty-two first-episode psychotic patients who were neuroleptic-naive were studied to examine predictors of acute dystonia after treatment with haloperidol."5.07Predictors of acute dystonia in first-episode psychotic patients. ( Aguilar, EJ; Gómez-Beneyto, M; Hernández, J; Keshavan, MS; Martínez-Quiles, MD; Schooler, NR, 1994)
" Dosage was chosen and adjusted to the individual patient's condition and response."2.67Zuclopenthixol and haloperidol in patients with acute psychotic states. A double-blind, multi-centre study. ( Eliander, H; Heikkilä, L; Pedersen, V; Turunen, M; Vartiainen, H, 1992)
"Aripiprazole is a new generation antipsychotic drug with a partial agonist effect on dopamine D2 and D3 receptors."1.35Aripiprazole in combination with other antipsychotic drugs may worsen psychosis. ( Adan-Manes, J; Garcia-Parajua, P, 2009)
" There were no significant metabolic or organic cerebral changes that could have accounted for the symptoms which presumably had been induced by the drugs even though their dosage was not unusual."1.29[Drug-induced asterixis]. ( Leblhuber, F; Rittmannsberger, H, 1994)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199011 (52.38)18.7374
1990's4 (19.05)18.2507
2000's2 (9.52)29.6817
2010's4 (19.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vingerhoets, C2
Bakker, G2
van Dijk, J1
Bloemen, OJN2
Wang, Y1
Chan, RCK1
Booij, J2
van Amelsvoort, TAMJ2
Escobar-Vidarte, MF1
Loaiza-Osorio, S1
Messa, AA1
Macías, GE1
Schrantee, A1
van der Pluijm, M1
Reneman, L1
Caan, M1
Adan-Manes, J1
Garcia-Parajua, P1
Varol Tas, F1
Guvenir, T1
Grootens, KP1
van Veelen, NM1
Peuskens, J1
Sabbe, BG1
Thys, E1
Buitelaar, JK1
Verkes, RJ1
Kahn, RS1
STEINBRECHER, W1
MATIAR-VAHAR, H1
Friis, T1
Christensen, TR1
Gerlach, J2
Aguilar, EJ1
Keshavan, MS1
Martínez-Quiles, MD1
Hernández, J1
Gómez-Beneyto, M1
Schooler, NR1
Meut, C1
Bavoux, F1
Cynober, E1
Lebrun, F1
Rittmannsberger, H1
Leblhuber, F1
Simmelsgaard, H1
Fruensgaard, K1
Korsgaard, S1
Jorgensen, H1
Jensen, K1
Yaryura-Tobias, JA1
Fledel, T1
Neziroglu, F1
Heikkilä, L1
Eliander, H1
Vartiainen, H1
Turunen, M1
Pedersen, V1
Kuniyoshi, M1
Inanaga, K1
Kammerer, T1
Schweitzer-Bucher, E1
Jamet, P1
Royer, M1
Orlov, P1
Kasparian, G1
DiMascio, A1
Cole, JO1
Meyer, HH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Double-Blind, Randomized Trial Of Ziprasidone (80 - 160 Mg) Versus Olanzapine (10 - 20 Mg) In Patients With Recent-Onset Schizophrenia, Schizoaffective And Schizophreniform Disorder.[NCT00145444]Phase 3100 participants Interventional2003-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for biperiden and Psychotic Disorders

ArticleYear
Neuroleptic malignant syndrome in pregnancy: case report and literature review.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2019, Volume: 32, Issue:14

    Topics: Anticonvulsants; Antipsychotic Agents; Biperiden; Female; Humans; Levetiracetam; Neuroleptic Maligna

2019

Trials

7 trials available for biperiden and Psychotic Disorders

ArticleYear
Influence of muscarinic M
    Psychiatry research. Neuroimaging, 2019, 08-30, Volume: 290

    Topics: Adult; Biperiden; Brain; Choline; Cognition; Corpus Striatum; Cross-Over Studies; Female; Gyrus Cing

2019
Ziprasidone vs olanzapine in recent-onset schizophrenia and schizoaffective disorder: results of an 8-week double-blind randomized controlled trial.
    Schizophrenia bulletin, 2011, Volume: 37, Issue:2

    Topics: Adult; Alanine Transaminase; Antipsychotic Agents; Aspartate Aminotransferases; Basal Ganglia Diseas

2011
Predictors of acute dystonia in first-episode psychotic patients.
    The American journal of psychiatry, 1994, Volume: 151, Issue:12

    Topics: Adolescent; Adult; Age Factors; Biperiden; Delusions; Double-Blind Method; Dystonia; Female; Haloper

1994
Tardive dyskinesia during and following treatment with haloperidol, haloperidol + biperiden, thioridazine, and clozapine.
    Psychopharmacology, 1978, Oct-31, Volume: 59, Issue:2

    Topics: Aged; Biperiden; Clinical Trials as Topic; Clozapine; Dibenzazepines; Drug Therapy, Combination; Dys

1978
Loxapine versus haloperidol parenterally in acute psychosis with agitation. A double-blind study.
    Acta psychiatrica Scandinavica, 1977, Volume: 56, Issue:4

    Topics: Acute Disease; Adult; Aged; Aggression; Biperiden; Clinical Trials as Topic; Dibenzoxazepines; Doubl

1977
Zuclopenthixol and haloperidol in patients with acute psychotic states. A double-blind, multi-centre study.
    Current medical research and opinion, 1992, Volume: 12, Issue:9

    Topics: Adult; Aged; Biperiden; Clopenthixol; Double-Blind Method; Drug Administration Schedule; Drug Therap

1992
Effect of different neuroleptics in tardive dyskinesia and parkinsonism. A video-controlled multicenter study with chlorprothixene, perphenazine, haloperidol and haloperidol + biperiden. Nordic Dyskinesia Study Group.
    Psychopharmacology, 1986, Volume: 90, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Biperiden; Chlorprothixene; Dyskinesia, Drug-I

1986

Other Studies

13 other studies available for biperiden and Psychotic Disorders

ArticleYear
The effect of the muscarinic M
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2017, Volume: 27, Issue:9

    Topics: Administration, Oral; Adult; Biperiden; Cognition; Cross-Over Studies; Female; Humans; Learning; Mal

2017
Aripiprazole in combination with other antipsychotic drugs may worsen psychosis.
    Journal of clinical pharmacy and therapeutics, 2009, Volume: 34, Issue:2

    Topics: Amisulpride; Anti-Dyskinesia Agents; Antipsychotic Agents; Aripiprazole; Biperiden; Dopamine; Drug T

2009
Amisulpride treatment of adolescent patients with schizophrenia or schizo-affective disorders.
    European child & adolescent psychiatry, 2009, Volume: 18, Issue:8

    Topics: Adolescent; Amisulpride; Antiparkinson Agents; Antipsychotic Agents; Biperiden; Dose-Response Relati

2009
[Akineton psychoses].
    Deutsche medizinische Wochenschrift (1946), 1958, Aug-15, Volume: 83, Issue:33

    Topics: Biperiden; Cardiovascular Agents; Mental Disorders; Muscle Relaxants, Central; Parkinson Disease; Ps

1958
[On an akineton induced psychosis with schizophrenic features].
    Der Nervenarzt, 1961, Volume: 32

    Topics: Biperiden; Humans; Mental Disorders; Parasympatholytics; Psychoses, Substance-Induced; Psychotic Dis

1961
Sodium valproate and biperiden in neuroleptic-induced akathisia, parkinsonism and hyperkinesia. A double-blind cross-over study with placebo.
    Acta psychiatrica Scandinavica, 1983, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Biperiden; Double-Blind Method; Drug Therapy, Combina

1983
Necrotizing enterocolitis in a newborn: maternal psychotropic drugs suspected.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1994, Volume: 39, Issue:2

    Topics: Adult; Biperiden; Chlorpromazine; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Female

1994
[Drug-induced asterixis].
    Deutsche medizinische Wochenschrift (1946), 1994, Apr-22, Volume: 119, Issue:16

    Topics: Biperiden; Clopenthixol; Clozapine; Drug Therapy, Combination; Electromyography; Female; Humans; Lit

1994
Vitamins, neuroleptics, and antiparkinsonian drugs in catecholamine excretion.
    Biological psychiatry, 1976, Volume: 11, Issue:3

    Topics: Adult; Antiparkinson Agents; Biperiden; Chlorpromazine; Dopamine; Epinephrine; Humans; Male; Nicotin

1976
Haloperidol and biperiden plasma levels in a pregnant atypical psychotic woman and a neonate--a case report.
    The Kurume medical journal, 1985, Volume: 32, Issue:3

    Topics: Adult; Biperiden; Female; Haloperidol; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Milk,

1985
[Study of the delayed-action form of a synthetic antiparkinsonian drug: Akineton].
    Annales medico-psychologiques, 1972, Volume: 1, Issue:5

    Topics: 1-Propanol; Adolescent; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Biperiden; Catatonia; D

1972
Withdrawal of antiparkinson drugs.
    Archives of general psychiatry, 1971, Volume: 25, Issue:5

    Topics: Biperiden; Butyrophenones; Female; Humans; Male; Parasympatholytics; Parkinson Disease; Psychotic Di

1971
[On the question of possible irreversible disorders due to psychopharmacotherapy].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1966, Volume: 208, Issue:4

    Topics: Adult; Autonomic Nervous System; Biperiden; Butyrophenones; Central Nervous System; Chlorpromazine;

1966