Page last updated: 2024-10-23

biperiden and Neuroleptic Malignant Syndrome

biperiden has been researched along with Neuroleptic Malignant Syndrome in 11 studies

Biperiden: A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
biperiden : A member of the class of piperidines that is N-propylpiperidine in which the methyl hydrogens have been replaced by hydroxy, phenyl, and 5-norbornen-2-yl groups. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all forms of Parkinson's disease.

Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)

Research Excerpts

ExcerptRelevanceReference
"This report describes a case of neuroleptic malignant syndrome due to risperidone in a child with Joubert syndrome."5.35Neuroleptic malignant syndrome due to risperidone treatment in a child with Joubert syndrome. ( Akin, R; Altun, D; Congologlu, A; Unay, B; Vurucu, S, 2009)
"We describe a case of neuroleptic malignant syndrome (NMS) associated with the use of ziprasidone."5.34Neuroleptic malignant syndrome induced by ziprasidone on the second day of treatment. ( Cansel, N; Herken, H; Ozen, ME; Savas, HA; Yumru, M, 2007)
"In a schizophrenic patient, hypothermia was caused by combined treatment with zotepine, biperiden, and fluphenazine, although combined treatment with zotepine and biperiden had caused no side effects."3.67Hypothermia caused by antipsychotic drugs in a schizophrenic patient. ( Hashimoto, H; Kamimura, H; Nakajima, T; Nakao, J; Noto, T; Okamoto, K; Sugae, S, 1987)
"This report describes a case of neuroleptic malignant syndrome due to risperidone in a child with Joubert syndrome."1.35Neuroleptic malignant syndrome due to risperidone treatment in a child with Joubert syndrome. ( Akin, R; Altun, D; Congologlu, A; Unay, B; Vurucu, S, 2009)
"We describe a case of neuroleptic malignant syndrome (NMS) associated with the use of ziprasidone."1.34Neuroleptic malignant syndrome induced by ziprasidone on the second day of treatment. ( Cansel, N; Herken, H; Ozen, ME; Savas, HA; Yumru, M, 2007)
"As the neuroleptic malignant syndrome ist rare many cases should be collected in order to enhance the knowledge of the etiology and the pathogenesis of that life--threatening complication of treatment with neuroleptic drugs."1.28[Neuroleptic malignant syndrome--a case report on diagnosis, differential diagnosis and therapy of a life threatening complication of treatment with neuroleptics]. ( Pflug, B; Staud, L, 1992)
"A case is reported, in which fatal pulmonary embolism complicated the course of a neuroleptic malignant syndrome (NMS)."1.28[Malignant neuroleptic syndrome: complete anticoagulant treatment or not?]. ( van Agtmael, MA; van Harten, PN, 1992)
"The authors describe a case report of catatonia syndrome after administration of depot neuroleptics."1.28Neuroleptic-induced catatonia: neuroleptic malignant syndrome? ( Alonso-Abolafia, A; de la Serna, I; de Leon, J; Munoz-Ruata, J; Pico-Soler, E; Saiz-Ruiz, J, 1990)
"The dominant symptom was deep coma."1.27Neuroleptic malignant syndrome: observations on altered consciousness. ( Deuschl, G; Hermle, L; Kindt, H; Oepen, G, 1987)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's4 (36.36)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Escobar-Vidarte, MF1
Loaiza-Osorio, S1
Messa, AA1
Macías, GE1
Vurucu, S1
Congologlu, A1
Altun, D1
Unay, B1
Akin, R1
Ozen, ME1
Yumru, M1
Savas, HA1
Cansel, N1
Herken, H1
Yoshida, K1
Takahashi, H1
Sato, K1
Higuchi, H1
Shimizu, T1
Staud, L1
Pflug, B1
van Agtmael, MA1
van Harten, PN1
de Leon, J1
Saiz-Ruiz, J1
Alonso-Abolafia, A1
Pico-Soler, E1
Munoz-Ruata, J1
de la Serna, I1
Usandizaga, I1
Pérez de Mendiola, MM1
Buades, J1
Martínez, J1
Deuschl, G1
Oepen, G1
Hermle, L1
Kindt, H1
Noto, T1
Hashimoto, H1
Sugae, S1
Okamoto, K1
Nakao, J1
Kamimura, H1
Nakajima, T1
Capellà Hereu, D1
Cabeza Gutés, D1
Laporte Roselló, JR1

Reviews

1 review available for biperiden and Neuroleptic Malignant Syndrome

ArticleYear
Neuroleptic malignant syndrome in pregnancy: case report and literature review.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2019, Volume: 32, Issue:14

    Topics: Anticonvulsants; Antipsychotic Agents; Biperiden; Female; Humans; Levetiracetam; Neuroleptic Maligna

2019

Other Studies

10 other studies available for biperiden and Neuroleptic Malignant Syndrome

ArticleYear
Neuroleptic malignant syndrome due to risperidone treatment in a child with Joubert syndrome.
    Journal of the National Medical Association, 2009, Volume: 101, Issue:3

    Topics: Abnormalities, Multiple; Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Antipsychotic Agents;

2009
Neuroleptic malignant syndrome induced by ziprasidone on the second day of treatment.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2007, Volume: 8, Issue:1

    Topics: Adult; Antipsychotic Agents; Biperiden; Diagnosis, Differential; Diazepam; Drug Therapy, Combination

2007
Biperiden hydrochlorate ameliorates dystonia of rats produced by microinjection of sigma ligands into the red nucleus.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:3

    Topics: Animals; Anti-Dyskinesia Agents; Anticonvulsants; Biperiden; Disease Models, Animal; Guanidines; Hal

2000
[Neuroleptic malignant syndrome--a case report on diagnosis, differential diagnosis and therapy of a life threatening complication of treatment with neuroleptics].
    Psychiatrische Praxis, 1992, Volume: 19, Issue:4

    Topics: Adult; Antipsychotic Agents; Benperidol; Biperiden; Delayed-Action Preparations; Humans; Male; Neuro

1992
[Malignant neuroleptic syndrome: complete anticoagulant treatment or not?].
    Nederlands tijdschrift voor geneeskunde, 1992, Sep-19, Volume: 136, Issue:38

    Topics: Adult; Anticoagulants; Biperiden; Depressive Disorder; Drug Therapy, Combination; Haloperidol; Human

1992
Neuroleptic-induced catatonia: neuroleptic malignant syndrome?
    Progress in neuro-psychopharmacology & biological psychiatry, 1990, Volume: 14, Issue:1

    Topics: Adult; Antipsychotic Agents; Biperiden; Catatonia; Delayed-Action Preparations; Diagnosis, Different

1990
[Neuroleptic malignant syndrome].
    Medicina clinica, 1990, Oct-06, Volume: 95, Issue:11

    Topics: Adult; Biperiden; Chlormethiazole; Chlorpromazine; Dantrolene; Diazepam; Female; Haloperidol; Humans

1990
Neuroleptic malignant syndrome: observations on altered consciousness.
    Pharmacopsychiatry, 1987, Volume: 20, Issue:4

    Topics: Adult; Biperiden; Brain; Cholinergic Fibers; Coma; Fever; Humans; Male; Neuroleptic Malignant Syndro

1987
Hypothermia caused by antipsychotic drugs in a schizophrenic patient.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:2

    Topics: Adult; Biperiden; Dibenzothiepins; Drug Therapy, Combination; Fluphenazine; Humans; Hypothermia; Mal

1987
[Malignant neuroleptic syndrome and biperiden].
    Medicina clinica, 1985, Nov-23, Volume: 85, Issue:17

    Topics: Biperiden; Haloperidol; Humans; Male; Middle Aged; Neuroleptic Malignant Syndrome; Piperidines

1985